Search Results - Alan N. Engelman
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HIV Capsid and Integration Targeting by Alan N. Engelman
Published in Viruses (2021-01-01)Get full text
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Multimodal Functionalities of HIV-1 Integrase by Alan N. Engelman, Mamuka Kvaratskhelia
Published in Viruses (2022-04-01)Get full text
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You can keep your coat on by Gregory J Bedwell, Alan N Engelman
Published in eLife (2021-06-01)Get full text
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Spatial and Genomic Correlates of HIV-1 Integration Site Targeting by Parmit Kumar Singh, Gregory J. Bedwell, Alan N. Engelman
Published in Cells (2022-02-01)Get full text
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HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Int... by Min Li, Zhen Li, Xuemin Chen, Yanxiang Cui, Alan N. Engelman, Robert Craigie
Published in Viruses (2024-07-01)Get full text
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Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins by Haley Flick, Ananya Venbakkam, Parmit K. Singh, Bailey Layish, Szu-Wei Huang, Rajalingam Radhakrishnan, Mamuka Kvaratskhelia, Alan N. Engelman, Melissa Kane
Published in mBio (2025-03-01)Get full text
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Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis by Jennifer L Elliott, Jenna E Eschbach, Pratibha C Koneru, Wen Li, Maritza Puray-Chavez, Dana Townsend, Dana Q Lawson, Alan N Engelman, Mamuka Kvaratskhelia, Sebla B Kutluay
Published in eLife (2020-09-01)Get full text
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The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir. by Szu-Wei Huang, Lorenzo Briganti, Arun S Annamalai, Juliet Greenwood, Nikoloz Shkriabai, Reed Haney, Michael L Armstrong, Michael F Wempe, Satya Prakash Singh, Ashwanth C Francis, Alan N Engelman, Mamuka Kvaratskhelia
Published in PLoS Pathogens (2025-01-01)Get full text
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Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration. by Irena Zurnic, Sylvia Hütter, Ute Rzeha, Nicole Stanke, Juliane Reh, Erik Müllers, Martin V Hamann, Tobias Kern, Gesche K Gerresheim, Fabian Lindel, Erik Serrao, Paul Lesbats, Alan N Engelman, Peter Cherepanov, Dirk Lindemann
Published in PLoS Pathogens (2016-08-01)Get full text
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CPSF6 promotes HIV-1 preintegration complex function by Evan Chaudhuri, Sooin Jang, Rajasree Chakraborty, Rajalingam Radhakrishnan, Bjarki Arnarson, Prem Prakash, Daphne Cornish, Nicholas Rohlfes, Parmit K. Singh, Jiong Shi, Christopher Aiken, Edward Campbell, Judd Hultquist, Muthukumar Balsubramaniam, Alan N. Engelman, Chandravanu Dash
Published in Journal of Virology (2025-05-01)Get full text
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Correction: Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration. by Irena Zurnic, Sylvia Hütter, Ute Rzeha, Roger Helbig, Nicole Stanke, Juliane Reh, Erik Müllers, Martin V Hamann, Tobias Kern, Gesche K Gerresheim, Fabian Lindel, Erik Serrao, Paul Lesbats, Alan N Engelman, Peter Cherepanov, Dirk Lindemann
Published in PLoS Pathogens (2016-10-01)Get full text
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The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function by Matthew R. Singer, Tung Dinh, Lev Levintov, Arun S. Annamalai, Juan S. Rey, Lorenzo Briganti, Nicola J. Cook, Valerie E. Pye, Ian A. Taylor, Kyungjin Kim, Alan N. Engelman, Baek Kim, Juan R. Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
Published in mBio (2023-02-01)Get full text
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Disrupting MLV integrase:BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model. by Lorenz Loyola, Vasudevan Achuthan, Kathryn Gilroy, Gillian Borland, Anna Kilbey, Nancy Mackay, Margaret Bell, Jodie Hay, Sriram Aiyer, Dylan Fingerman, Rodrigo A Villanueva, Ewan Cameron, Christine A Kozak, Alan N Engelman, James Neil, Monica J Roth
Published in PLoS Pathogens (2019-12-01)Get full text
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Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration by Zachary Ingram, Christopher Kline, Alexandra K. Hughson, Parmit K. Singh, Hannah L. Fischer, Rajalingham Radhakrishnan, Gregory A. Sowd, Nayara F. B. Dos Santos, Barbie K. Ganser-Pornillos, Simon C. Watkins, Melissa Kane, Alan N. Engelman, Zandrea Ambrose
Published in mBio (2025-04-01)Get full text
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HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors by Pratibha C Koneru, Ashwanth C Francis, Nanjie Deng, Stephanie V Rebensburg, Ashley C Hoyte, Jared Lindenberger, Daniel Adu-Ampratwum, Ross C Larue, Michael F Wempe, Alan N Engelman, Dmitry Lyumkis, James R Fuchs, Ronald M Levy, Gregory B Melikyan, Mamuka Kvaratskhelia
Published in eLife (2019-05-01)Get full text
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Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir by Lorenzo Briganti, Arun S. Annamalai, Stephanie M. Bester, Guochao Wei, Jonathan R. Andino-Moncada, Satya P. Singh, Alex B. Kleinpeter, Meghna Tripathi, Binh Nguyen, Rajalingam Radhakrishnan, Parmit K. Singh, Juliet Greenwood, Lauren I. Schope, Reed Haney, Szu-Wei Huang, Eric O. Freed, Alan N. Engelman, Ashwanth C. Francis, Mamuka Kvaratskhelia
Published in mBio (2025-05-01)Get full text
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