Search Results - Bryan T Hennessy

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  1. 1

    Obesity Correlation With Metastases Development and Response to First-Line Metastatic Chemotherapy in Breast Cancer by Mohammed A. Osman, Bryan T. Hennessy

    Published in Clinical Medicine Insights: Oncology (2015-11-01)
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  2. 2

    Case report: Clonal evolution analysis of a rare case of meningioma lung metastases identifies actionable alterations in matched longitudinal tumour samples by Nicola Cosgrove, Orla M. Fitzpatrick, Orla M. Fitzpatrick, Liam Grogan, Liam Grogan, Bryan T. Hennessy, Bryan T. Hennessy, Simon J. Furney, Sinead Toomey

    Published in Frontiers in Oncology (2025-01-01)
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  3. 3

    Contrasting roles of KMT2C and KMT2D in breast cancer by Emily Tinsley, Philip Bredin, Sinead Toomey, Bryan T. Hennessy, Simon J. Furney

    Published in Scientific Reports (2025-10-01)
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  4. 4

    Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro by Ozlem Aslan, Mattia Cremona, Clare Morgan, Lydia W. Cheung, Gordon B. Mills, Bryan T. Hennessy

    Published in BMC Cancer (2018-02-01)
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  5. 5

    Dynamic platelet function is markedly different in patients with cancer compared to healthy donors by Jonathan Cowman, Louis Richter, Roisin Walsh, Niamh Keegan, Willard Tinago, Antonio J. Ricco, Bryan T Hennessy, Dermot Kenny, Eimear Dunne

    Published in Platelets (2019-08-01)
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  6. 6

    Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors by Constantin Jotzu, Eckhard Alt, Gabriel Welte, Jie Li, Bryan T. Hennessy, Eswaran Devarajan, Srinivasalu Krishnappa, Severin Pinilla, Lilly Droll, Yao-Hua Song

    Published in Analytical Cellular Pathology (2010-01-01)
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  7. 7

    Operational determinants of recruitment and biospecimen collection in translational observational studies: a multi-site comparative analysis by Ciarán Devoy, Ronan Andrew McLaughlin, Christopher Cronin, Rachel Clarke, Roisin M. Connolly, Erin Crowley, Laia Raigal, Dearbhaile Collins, Brian Bird, Bryan T. Hennessy, Mark Tangney

    Published in Journal of Translational Medicine (2025-10-01)
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  8. 8

    Preclinical evaluation of the CDK4/6 inhibitor palbociclib in combination with a PI3K or MEK inhibitor in colorectal cancer by Cha Len Lee, Mattia Cremona, Angela Farrelly, Julie A. Workman, Sean Kennedy, Razia Aslam, Aoife Carr, Stephen Madden, Brian O’Neill, Bryan T. Hennessy, Sinead Toomey

    Published in Cancer Biology & Therapy (2023-12-01)
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  9. 9

    Review of the status of neoadjuvant therapy in HER2-positive breast cancer by Gavin P. Dowling, Gavin P. Dowling, Gavin P. Dowling, Stephen Keelan, Stephen Keelan, Sinead Toomey, Gordon R. Daly, Gordon R. Daly, Bryan T. Hennessy, Arnold D. K. Hill, Arnold D. K. Hill

    Published in Frontiers in Oncology (2023-01-01)
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  10. 10

    Neratinib plus dasatinib is highly synergistic in HER2-positive breast cancer in vitro and in vivo by Neil T Conlon, Sandra Roche, Amira F Mahdi, Alacoque Browne, Laura Breen, Johanna Gaubatz, Justine Meiller, Fiona O'Neill, Lorraine O'Driscoll, Mattia Cremona, Bryan T Hennessy, Lisa D Eli, John Crown, Denis M Collins

    Published in Translational Oncology (2024-11-01)
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  11. 11

    Similar overall survival with reduced vs. standard dose bevacizumab monotherapy in progressive glioblastoma by Jack Patrick Gleeson, Fergus Keane, Niamh M. Keegan, Emin Mammadov, Emily Harrold, Abdullah Alhusaini, Jeffrey Harte, Austin Eakin‐Love, Philip J. O'Halloran, Stephen MacNally, Bryan T. Hennessy, Oscar S. Breathnach, Liam Grogan, Patrick G. Morris

    Published in Cancer Medicine (2020-01-01)
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  12. 12

    Neoadjuvant trastuzumab deruxtecan (T-DXd) with response-directed definitive therapy in early stage HER2-positive breast cancer: a phase II study protocol (SHAMROCK study) by Gavin P. Dowling, Sinead Toomey, Philip Bredin, Imelda Parker, Eibhlin Mulroe, Jacinta Marron, Olivia McLoughlin, Ausra Teiserskiene, Colm Power, Anne Marie O’Shea, Megan Greally, Patrick G. Morris, Deirdre Duke, Arnold D. K. Hill, Bryan T. Hennessy

    Published in BMC Cancer (2024-01-01)
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  13. 13

    Targeting the phosphatidylinositol-3-kinase (PI3K) and mitogen activated protein kinase (MAPK) signalling pathways to enhance chemoradiotherapy in locally advanced rectal cancer by Aoife Carr, Jonathan A. Coulter, Julie Workman, Joanna Fay, Angela Farrelly, Alex J. Eustace, Lindsey Bennie, Liam Grogan, Oscar Breathnach, Patrick G. Morris, Deborah A. McNamara, Mattia Cremona, Brian D.P. O'Neill, Bryan T. Hennessy, Sinead Toomey

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  14. 14

    Prevalence of tumor BRCA1 and BRCA2 dysfunction in unselected patients with ovarian cancer by Roshni D. Kalachand, Ciaran O’Riain, Sinead Toomey, Aoife Carr, Kirsten M. Timms, Sharon O’Toole, Stephen Madden, Mark Bates, John J. O’Leary, Noreen Gleeson, Dearbhaile O’Donnell, Liam Grogan, Oscar Breathnach, Angela Farrelly, Britta Stordal, Bryan T. Hennessy

    Published in Obstetrics & Gynecology Science (2020-09-01)
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  15. 15

    Neoadjuvant chemoradiation in older Irish adult patients with oesophageal cancer: a retrospective institutional review of clinical outcomes and hematological toxicity by Ronan Andrew McLaughlin, David McMahon, Christopher Cluxton, Orla Meave Fitzpatrick, Michael Conroy, Majid Almeraikhi, Humaid Alkaabi, Fianait Bligh, Brian O’Neill, Mayilone Arumugasamy, William Robb, Oscar Seamus Breathnach, William Grogan, Bryan T. Hennessy, Adrian Murphy, Jarsuhka Naidoo, Megan Greally, Kathleen Bennett, Patrick G Morris

    Published in BMC Cancer (2025-08-01)
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  16. 16

    Molecular subtyping of endometrial carcinoma cell lines uncovers subtype-specific targetable vulnerabilities by Eunice S. Li, Rebecca Ho, Ran Tao, Yannes Wai Yan Choi, Chae Young Shin, Shary Y. Chen, Bengul Gokbayrak, Janine Senz, Betty Yao, Liam Johnston, Spencer D. Martin, Eric Yang, Mark S. Carey, Bryan T. Hennessy, David G. Huntsman, Ramon I. Klein Geltink, Lynn Hoang, Yemin Wang

    Published in npj Precision Oncology (2025-07-01)
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  17. 17

    Prognostic Significance of Delays in Initiation of Adjuvant Trastuzumab-Based Therapy in Patients with HER2-Positive Breast Cancer by Gavin P. Dowling, Aisling Hegarty, Gordon R. Daly, Sandra Hembrecht, Cian M. Hehir, Gavin G. Calpin, Richard Hogan, David O’Reilly, Eithne Downey, Sinead Toomey, Liam Grogan, Oscar Breathnach, Michael Allen, Patrick G. Morris, Colm Power, Leonie S. Young, Arnold D. K. Hill, Bryan T. Hennessy

    Published in Biomedicines (2025-05-01)
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  18. 18

    TCHL – a phase II neo-adjuvant study assessing TCH (docetaxel, carboplatin and trastuzumab) and TCHL (docetaxel, carboplatin, rastuzumab and lapatinib) in HER-2 positive breast can... by John Crown, Alex J. Eustace, Denis M. Collins, Maccon Keane, Linda Coate, John Kennedy, Seamus O'Reilly, Catherine Kelly, Miriam O'Connor, Michael Martin, Conleth Murphy, Karen Duffy, Janice Walshe, Giuseppe Gullo, Thamir Mahgoub, Alberto Alvarez-Iglesias, Imelda Parker, Vicky Donachie, Ausra Teiserskiene, Stephen F. Madden, Brian Moulton, Norma O'Donovan, Bryan T. Hennessy

    Published in Acta Oncologica (2025-06-01)
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  19. 19

    Predictive modelling of response to neoadjuvant therapy in HER2+ breast cancer by Nicola Cosgrove, Alex J. Eustace, Peter O’Donovan, Stephen F. Madden, Bruce Moran, John Crown, Brian Moulton, Patrick G. Morris, Liam Grogan, Oscar Breathnach, Colm Power, Michael Allen, Janice M. Walshe, Arnold D. Hill, Anna Blümel, Darren O’Connor, Sudipto Das, Małgorzata Milewska, Joanna Fay, Elaine Kay, Sinead Toomey, Bryan T. Hennessy, Simon J. Furney

    Published in npj Breast Cancer (2023-09-01)
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  20. 20

    A phase Ia study of the MEK1/2 inhibitor PD-0325901 with the c-MET inhibitor crizotinib in patients with advanced solid cancers by Peter Gallagher, Christian Rolfo, Elena Elez, Julien Taieb, Jennifer Houlden, Linda Collins, Corran Roberts, Thierry André, Mark Lawler, Federica Di Nicolantonio, Margaret Grayson, Ruth Boyd, Vlad Popovici, Alberto Bardelli, Robbie Carson, Hajrah Khawaja, Pierre Laurent-Puig, Manuel Salto-Tellez, Bryan T. Hennessy, Tim S. Maughan, Josep Tabernero, Richard Adams, Robert Jones, Marc Peeters, Mark R. Middleton, Richard H. Wilson, Sandra Van Schaeybroeck, on behalf of the MErCuRIC Trial Consortium

    Published in BJC Reports (2025-03-01)
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