Search Results - Tomas Cihlar
- Showing 1 - 16 results of 16
-
1
-
2
-
3
Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleos(t)ide therap... by Dara L Burdette, Scott Lazerwith, Jenny Yang, Henry L Y Chan, William E Delaney Iv, Simon P Fletcher, Tomas Cihlar, Becket Feierbach
Published in PLoS ONE (2022-01-01)Get full text
Article -
4
Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells. by Mini Balakrishnan, Stephen R Yant, Luong Tsai, Christopher O'Sullivan, Rujuta A Bam, Angela Tsai, Anita Niedziela-Majka, Kirsten M Stray, Roman Sakowicz, Tomas Cihlar
Published in PLoS ONE (2013-01-01)Get full text
Article -
5
Effect of remdesivir post-exposure prophylaxis and treatment on pathogenesis of measles in rhesus macaques by Nadine A. Peart Akindele, Laharika Dasharath Katamoni, Jacqueline Brockhurst, Shristi Ghimire, San Suwanmanee, Lisa Pieterse, Kelly A. Metcalf Pate, Elaine Bunyan, Roy Bannister, Tomas Cihlar, Danielle P. Porter, Diane E. Griffin
Published in Scientific Reports (2023-04-01)Get full text
Article -
6
Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells. by Derek D Sloan, Chia-Ying Kao Lam, Alivelu Irrinki, Liqin Liu, Angela Tsai, Craig S Pace, Jasmine Kaur, Jeffrey P Murry, Mini Balakrishnan, Paul A Moore, Syd Johnson, Jeffrey L Nordstrom, Tomas Cihlar, Scott Koenig
Published in PLoS Pathogens (2015-01-01)Get full text
Article -
7
The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabine Are Inactive against SARS-CoV-2 by Joy Y. Feng, Venice Du Pont, Darius Babusis, Calvin J. Gordon, Egor P. Tchesnokov, Jason K. Perry, Vincent Duong, Arya Vijjapurapu, Xiaofeng Zhao, Julie Chan, Cal Cohen, Kavita Juneja, Tomas Cihlar, Matthias Götte, John P. Bilello
Published in Molecules (2022-06-01)Get full text
Article -
8
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19 by Xuping Xie, Antonio E. Muruato, Xianwen Zhang, Kumari G. Lokugamage, Camila R. Fontes-Garfias, Jing Zou, Jianying Liu, Ping Ren, Mini Balakrishnan, Tomas Cihlar, Chien-Te K. Tseng, Shinji Makino, Vineet D. Menachery, John P. Bilello, Pei-Yong Shi
Published in Nature Communications (2020-10-01)Get full text
Article -
9
Remdesivir postexposure prophylaxis limits measles-induced “immune amnesia” and measles antibody responses in macaques by Andy Kwan Pui Chan, Liting Liu, William R. Morgenlander, Manjusha Thakar, Nadine A. Peart Akindele, Jacqueline Brockhurst, Shristi Ghimire, Maggie L. Bartlett, Kelly A. Metcalf Pate, Victor C. Chu, Meghan S. Vermillion, Danielle P. Porter, Tomas Cihlar, Michael J. Mina, H. Benjamin Larman, Diane E. Griffin
Published in JCI Insight (2025-06-01)Get full text
Article -
10
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV by Timothy P. Sheahan, Amy C. Sims, Sarah R. Leist, Alexandra Schäfer, John Won, Ariane J. Brown, Stephanie A. Montgomery, Alison Hogg, Darius Babusis, Michael O. Clarke, Jamie E. Spahn, Laura Bauer, Scott Sellers, Danielle Porter, Joy Y. Feng, Tomas Cihlar, Robert Jordan, Mark R. Denison, Ralph S. Baric
Published in Nature Communications (2020-01-01)Get full text
Article -
11
Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing. by Datsen George Wei, Vicki Chiang, Elizabeth Fyne, Mini Balakrishnan, Tiffany Barnes, Michael Graupe, Joseph Hesselgesser, Alivelu Irrinki, Jeffrey P Murry, George Stepan, Kirsten M Stray, Angela Tsai, Helen Yu, Jonathan Spindler, Mary Kearney, Celsa A Spina, Deborah McMahon, Jacob Lalezari, Derek Sloan, John Mellors, Romas Geleziunas, Tomas Cihlar
Published in PLoS Pathogens (2014-04-01)Get full text
Article -
12
Activating PKC-ε induces HIV expression with improved tolerability. by Alivelu M Irrinki, Jasmine Kaur, Bally Randhawa, Ryan McFadden, Chelsea Snyder, Hoa Truong, Daniel Soohoo, Eric Hu, Helen Yu, Bernard P Murray, Bing Lu, Dmytro Kornyeyev, Ishak Darryl Irwan, Lan Nguyen, Yu-San Yang, Jean-Philippe Belzile, Uli Schmitz, Todd C Appleby, Brian Schultz, Jay Lalezari, Steven Deeks, Tomas Cihlar, Jeffrey P Murry
Published in PLoS Pathogens (2025-02-01)Get full text
Article -
13
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro by Sheli R. Radoshitzky, Patrick Iversen, Xianghan Lu, Jing Zou, Suzanne J. F. Kaptein, Kelly S. Stuthman, Sean A. Van Tongeren, Jesse Steffens, Ruoyu Gong, Hoa Truong, Annapurna A. Sapre, Huiling Yang, Xiaodong Xie, Jia Jun Chia, Zhijuan J. Song, Stacey M. Leventhal, Josolyn Chan, Alex Shornikov, Xin Zhang, David Cowfer, Helen Yu, Travis Warren, Tomas Cihlar, Danielle P. Porter, Johan Neyts, Pei-Yong Shi, Jay Wells, John P. Bilello, Joy Y. Feng
Published in Scientific Reports (2023-02-01)Get full text
Article -
14
Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing by Elizabeth E. Zumbrun, Carly B. Garvey, Jay B. Wells, Ginger C. Lynn, Sean Van Tongeren, Jesse T. Steffens, Kelly S. Wetzel, Laura M. Gomba, Kristan A. O’Brien, Franco D. Rossi, Xiankun Zeng, Eric D. Lee, Jo Lynne W. Raymond, Diana A. Hoffman, Alexandra N. Jay, Elizabeth S. Brown, Paul A. Kallgren, Sarah L. Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C. Chu, Bali Singh, Roy Bannister, Danielle P. Porter, Tomas Cihlar, John M. Dye
Published in Viruses (2023-11-01)Get full text
Article -
15
Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys by Jared Pitts, J. Lizbeth Reyes Zamora, Savrina Manhas, Thomas Aeschbacher, Josolyn Chan, Vincent Cutillas, Varsha Nair, Nicholas C. Riola, Arya Vijjapurapu, Meghan S. Vermillion, Stacey Eng, Christopher Richards, Dong Han, Jason K. Perry, Subhra Chaudhuri, Szu-Wen Liu, Clarissa Martinez, Nadine Peinovich, Kai-Hui Sun, Arthur Cai, Ross Martin, Jasmine Moshiri, Charlotte Hedskog, Darius Babusis, Dustin S. Siegel, Rao Kalla, Vasanthi Avadhanula, Pedro A. Piedra, Kim Stobbelaar, Peter L. Delputte, Caleb Marceau, Roberto Mateo, Evguenia Maiorova, Hongmei Mo, Raju Subramanian, Richard L. Mackman, Tomas Cihlar, Simon P. Fletcher, John P. Bilello
Published in Nature Communications (2025-07-01)Get full text
Article -
16
A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques by Elizabeth E. Zumbrun, Carly B. Garvey, Jay B. Wells, Ginger C. Lynn, Sean A. Van Tongeren, Jesse T. Steffens, Kelly S. Wetzel, Darrell L. Wetzel, Heather L. Esham, Nicole L. Garza, Eric D. Lee, Jennifer L. Scruggs, Franco D. Rossi, Elizabeth S. Brown, Jessica M. Weidner, Laura M. Gomba, Kristan A. O’Brien, Alexandra N. Jay, Xiankun Zeng, Kristen S. Akers, Paul A. Kallgren, Ethan Englund, J. Matthew Meinig, Jeffrey R. Kugelman, Joshua L. Moore, Holly A. Bloomfield, Sarah L. Norris, Tameka Bryan, Christie H. Scheuerell, Jesse Walters, Nevena Mollova, Christiana Blair, Darius Babusis, Tomas Cihlar, Danielle P. Porter, Bali Singh, Charlotte Hedskog, Sina Bavari, Travis K. Warren, Roy Bannister
Published in Viruses (2024-12-01)Get full text
Article