Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress.

by Chen-Hua Chuang, Marsha D Wallace, Christian Abratte, Teresa Southard, John C Schimenti
Published 2010-09-01

Rova-T enhances the anti-tumor activity of anti-PD1 in a murine model of small cell lung cancer with endogenous Dll3 expression

by Philip Vitorino, Chen-Hua Chuang, Alexandre Iannello, Xi Zhao, Wade Anderson, Ronald Ferrando, Zhaomei Zhang, Shravanthi Madhavan, Holger Karsunky, Laura R. Saunders
Published 2021-01-01

Axon-like protrusions promote small cell lung cancer migration and metastasis

by Dian Yang, Fangfei Qu, Hongchen Cai, Chen-Hua Chuang, Jing Shan Lim, Nadine Jahchan, Barbara M Grüner, Christin S Kuo, Christina Kong, Madeleine J Oudin, Monte M Winslow, Julien Sage
Published 2019-12-01

A Conditional System to Specifically Link Disruption of Protein-Coding Function with Reporter Expression in Mice

by Shin-Heng Chiou, Caroline Kim-Kiselak, Viviana I. Risca, Megan K. Heimann, Chen-Hua Chuang, Aurora A. Burds, William J. Greenleaf, Tyler E. Jacks, David M. Feldser, Monte M. Winslow
Published 2014-06-01

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer

by Adrian Vallejo, Naiara Perurena, Elisabet Guruceaga, Pawel K. Mazur, Susana Martinez-Canarias, Carolina Zandueta, Karmele Valencia, Andrea Arricibita, Dana Gwinn, Leanne C. Sayles, Chen-Hua Chuang, Laura Guembe, Peter Bailey, David K. Chang, Andrew Biankin, Mariano Ponz-Sarvise, Jesper B. Andersen, Purvesh Khatri, Aline Bozec, E. Alejandro Sweet-Cordero, Julien Sage, Fernando Lecanda, Silve Vicent
Published 2017-02-01