Integrated Molecular Analysis Indicates Undetectable Change in DNA Damage in Mice after Continuous Irradiation at ~ 400-fold Natural Background Radiation

by Olipitz, Werner, Shuga, Joe, Pang, Bo, McFaline, Jose Luis, Lonkar, Pallavi, Thomas, Aline, Mutamba, James Tendai, Greenberger, Joel S., Samson, Leona D., Dedon, Peter C., Yanch, Jacquelyn C., Engelward, Bevin P., Wiktor-Brown, Dominika
Published 2012

Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa

by Jaroensuk, Juthamas, Atichartpongkul, Sopapan, Wong, Yee Hwa, Liew, Chong Wai, McBee, Megan E., Thongdee, Narumon, Prestwich, Erin G., Mongkolsuk, Skorn, Lescar, Julien, Fuangthong, Mayuree, Chionh, Yok Hian, DeMott, Michael S, Dedon, Peter C
Published 2017

Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis

by Zhong, Wenhe, Guo, Jingjing, Cui, Liang, Chionh, Yok Hian, Li, Kuohan, El Sahili, Abbas, Cai, Qixu, Yuan, Meng, Michels, Paul A.M, Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D., Mu, Yuguang, Lescar, Julien, Dedon, Peter C
Published 2020

Novel genomic island modifies DNA with 7-deazaguanine derivatives

by Thiaville, Jennifer J., Yuan, Yifeng, Hutinet, Geoffrey, Thiaville, Patrick C., Brochier-Armanet, Celine, Letarov, Andrey V., Malik, Chanchal K., Rizzo, Carmelo J., de Crécy-Lagard, Valérie, Kellner, Stefanie M, Jumpathong, Watthanachai, Mohapatra, Susovan, Hillebrand, Roman, Dedon, Peter C
Published 2017

Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease

by Knutson, Charles G. F., Mangerich, Aswin, Zeng, Yu, Raczynski, Arkadiusz R., Liberman, Rosa G., Kang, Pilsoo, Ye, Wenjie, Prestwich, Erin, Lu, Kun, Wishnok, John S., Korzenik, Joshua R., Wogan, Gerald N., Fox, James G., Dedon, Peter C., Tannenbaum, Steven Robert
Published 2015

Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA

by Wang, Jin, Alvin Chew, Bing Liang, Lai, Yong, Dong, Hongping, Xu, Luang, Balamkundu, Seetharamsingh, Cai, Weiling Maggie, Cui, Liang, Liu, Chuan Fa, Fu, Xin-Yuan, Lin, Zhenguo, Shi, Pei-Yong, Lu, Timothy K, Luo, Dahai, Jaffrey, Samie R, Dedon, Peter C
Published 2020

Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N¹)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism

by Zhong, Wenhe, Pasunooti, Kalyan Kumar, Balamkundu, Seetharamsing, Wong, Yee Hwa, Nah, Qianhui, Gadi, Vinod, Gnanakalai, Shanmugavel, Chionh, Yok Hian, McBee, Megan E., Gopal, Pooja, Lim, Siau Hoi, Olivier, Nelson, Buurman, Ed T., Dick, Thomas, Liu, Chuan Fa, Lescar, Julien, Dedon, Peter C
Published 2019

Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer

by Mangerich, Aswin, Knutson, Charles G. F., Parry, Nicola Maria Anne, Muthupalani, Sureshkumar, Ye, Wenjie, Prestwich, Erin, Cui, Liang, McFaline, Jose Luis, Mobley, Melissa W., Ge, Zhongming, Taghizadeh, Koli, Wishnok, John S., Wogan, Gerald N., Fox, James G., Tannenbaum, Steven Robert, Dedon, Peter C.
Published 2013

The m⁶A Pathway Facilitates Sex Determination in Drosophila

by Kan, Lijuan, Grozhik, Anya V., Vedanayagam, Jeffrey, Patil, Deepak P., Pang, Nan, Huang, Yi-Chun, Joseph, Brian, Lin, Ching-Jung, Despic, Vladimir, Guo, Jian, Yan, Dong, Kondo, Shu, Deng, Wu-Min, Jaffrey, Samie R., Lai, Eric C., Lim, Kok Seong, Dedon, Peter C
Published 2018

DNA phosphorothioation is widespread and quantized in bacterial genomes

by Wang, Lianrong, Chen, Shi, Vergin, Kevin L., Giovannoni, Stephen J., Chan, Simon W., DeMott, Michael S., Taghizadeh, Koli, Cordero Sanchez, Otto Xavier, Cutler, Michael Barry, Timberlake, Sonia, Alm, Eric J., Polz, Martin F., Pinhassi, Jarone, Deng, Zixin, Dedon, Peter C., Chan, Simon W.
Published 2011

A multidimensional platform for the purification of non-coding RNA species

by McBee, Megan E., Su, Dan, Pang, Yan Ling Joy, Gu, Chen, Prestwich, Erin, Dedon, Peter C., Chionh, Yok Hian, Ho, Chia-Hua, Pruksakorn, Dumnoensun, Indrakanti, Ramesh Babu, Ng, Chee Sheng, Hia, Fabian, Dong, Hongping, Shi, Pei-Yong, Preiser, Peter Rainer, Alonso, Sylvie
Published 2013

Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens

by Rogers, Arlin B., Fry, Rebecca C., Dedon, Peter C., Tannenbaum, Steven Robert, Schauer, David B., Essigmann, John M., McFaline, Jose Luis, Williams, Michelle V., Doernte, A. L., Fiala, Jeannette Louise Allen, Raczynski, Arkadiusz R., Theve, E. J., Feng, Yan, Fox, James G., Lemon, S. M., Weinman, S. A.
Published 2010

m[superscript 6]A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

by Batista, Pedro J, Molinie, Benoit, Wang, Jinkai, Qu, Kun, Zhang, Jiajing, Li, Lingjie, Bouley, Donna M, Lujan, Ernesto, Haddad, Bahareh, Daneshvar, Kaveh, Carter, Ava C, Flynn, Ryan A, Zhou, Chan, Wernig, Marius, Mullen, Alan C, Xing, Yi, Giallourakis, Cosmas C, Chang, Howard Y, Lim, Kok Seong, Dedon, Peter C
Published 2017

Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences

by Cao, Bo, Chen, Chao, DeMott, Michael S., Cheng, Qiuxiang, Clark, Tyson A., Xiong, Xiaolin, Zheng, Xiaoqing, Levine, Stuart S., Yuan, George, Boitano, Matthew, Luong, Khai, Song, Yi, Zhou, Xiufen, Deng, Zixin, Turner, Stephen W., Korlach, Jonas, You, Delin, Wang, Lianrong, Chen, Shi, Butty, Vincent L G, Dedon, Peter C
Published 2015

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification

by Santos, Maria C. Ferreira dos, Anderson, Cole P., Neschen, Susanne, Zumbrennen-Bullough, Kimberly B., Romney, Steven J., Kahle-Stephan, Melanie, Rathkolb, Birgit, Gailus-Durner, Valerie, Fuchs, Helmut, Wolf, Eckhard, Rozman, Jan, de Angelis, Martin Hrabe, Cai, Weiling Maggie, Rajan, Malini, Hu, Jennifer, Dedon, Peter C, Leibold, Elizabeth A.
Published 2020

Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network

by Keegan, Caroline, Krutzik, Stephan, Schenk, Mirjam, Scumpia, Phillip O., Pang, Yan Ling Joy, Russell, Brandon S, Lim, Kok Seong, Shell, Scarlet, Prestwich, Erin, Su, Dan, Elashoff, David, Hershberg, Robert M., Bloom, Barry R., Belisle, John T., Fortune, Sarah, Dedon, Peter C, Pellegrini, Matteo, Modlin, Robert L., Lu, Jing,Ph.D.Massachusetts Institute of Technology
Published 2020

Opportunities to integrate new approaches in genetic toxicology: An ILSI-HESI workshop report

by Zeiger, Errol, Gollapudi, Bhaskar, Aardema, Marilyn J., Auerbach, Scott, Boverhof, Darrell, Custer, Laura, Honma, Masamitsu, Ishida, Seiichi, Kasinski, Andrea L., Kim, James H., Manjanatha, Mugimane G., Marlowe, Jennifer, Pfuhler, Stefan, Pogribny, Igor, Slikker, William, Stankowski, Leon F., Tanir, Jennifer Y., Tice, Raymond, van Benthem, Jan, White, Paul, Witt, Kristine L., Thybaud, Véronique, Dedon, Peter C.
Published 2015