A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling

by Kislay Parvatiyar, Jose Pindado, Anurupa Dev, Saba Roghiyh Aliyari, Shivam A. Zaver, Hoda Gerami, Maxime Chapon, Amir A. Ghaffari, Anant Dhingra, Genhong Cheng
Published 2018-07-01

ADP-ribosyltransferase PARP11 suppresses Zika virus in synergy with PARP12

by Lili Li, Yueyue Shi, Sirui Li, Junxiao Liu, Shulong Zu, Xin Xu, Meiling Gao, Nina Sun, Chaohu Pan, Linan Peng, Heng Yang, Genhong Cheng
Published 2021-06-01

Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses.

by Philip T Liu, Mirjam Schenk, Valencia P Walker, Paul W Dempsey, Melissa Kanchanapoomi, Matthew Wheelwright, Aria Vazirnia, Xiaoran Zhang, Andreas Steinmeyer, Ulrich Zügel, Bruce W Hollis, Genhong Cheng, Robert L Modlin
Published 2009-06-01

Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation

by Guangyun Tan, Zhaohong Yi, Hongxiao Song, Fengchao Xu, Feng Li, Roghiyh Aliyari, Hong Zhang, Peishuang Du, Yanhua Ding, Junqi Niu, Xiaosong Wang, Lishan Su, F. Xiao-Feng Qin, Genhong Cheng
Published 2019-12-01

Disruption of Type I Interferon Induction by HIV Infection of T Cells.

by David Jesse Sanchez, Daniel Miranda, Matthew D Marsden, Thomas Michael A Dizon, Johnny R Bontemps, Sergio J Davila, Lara E Del Mundo, Thai Ha, Ashkon Senaati, Jerome A Zack, Genhong Cheng
Published 2015-01-01

Gravidity-dependent associations between interferon response and birth weight in placental malaria

by Natalie M. Quanquin, Lauren G. Barres, Saba R. Aliyari, Nathan T. Day, Hoda Gerami, Susan J. Fisher, Abel Kakuru, Moses R. Kamya, Diane V. Havlir, Margaret Feeney, Grant Dorsey, Genhong Cheng, Stephanie L. Gaw
Published 2020-08-01

Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice.

by John S Cho, Yi Guo, Romela Irene Ramos, Frank Hebroni, Seema B Plaisier, Caiyun Xuan, Jennifer L Granick, Hironori Matsushima, Akira Takashima, Yoichiro Iwakura, Ambrose L Cheung, Genhong Cheng, Delphine J Lee, Scott I Simon, Lloyd S Miller
Published 2012-01-01

Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex

by Nina Sun, Chunfeng Li, Xiao-Feng Li, Yong-Qiang Deng, Tao Jiang, Na-Na Zhang, Shulong Zu, Rong-Rong Zhang, Lili Li, Xiang Chen, Ping Liu, Sarah Gold, Ning Lu, Peishuang Du, Jingfeng Wang, Cheng-Feng Qin, Genhong Cheng
Published 2020-11-01

Zika Virus Infection Leads to Variable Defects in Multiple Neurological Functions and Behaviors in Mice and Children

by Ziqi Zhao, Ziwei Shang, Zilton Vasconcelos, Chunfeng Li, Yisheng Jiang, Shulong Zu, Jingyi Zhang, Fengchao Wang, Li Yao, Jae U. Jung, Patricia Brasil, Maria Elisabeth Moreira, Cheng‐Feng Qin, Tara Kerin, Karin Nielsen‐Saines, Genhong Cheng, Xiaohui Zhang, Zhiheng Xu
Published 2020-09-01

Zika virus shedding in the stool and infection through the anorectal mucosa in mice

by Chunfeng Li, Yong-Qiang Deng, Shulong Zu, Natalie Quanquin, Jingzhe Shang, Min Tian, Xue Ji, Na-Na Zhang, Hao-Long Dong, Yan-Peng Xu, Ling-Zhai Zhao, Fu-Chun Zhang, Xiao-Feng Li, Aiping Wu, Genhong Cheng, Cheng-Feng Qin
Published 2018-10-01

Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice

by Chunfeng Li, Xingliang Zhu, Xue Ji, Natalie Quanquin, Yong-Qiang Deng, Min Tian, Roghiyh Aliyari, Xiangyang Zuo, Ling Yuan, Shabbir Khan Afridi, Xiao-Feng Li, Jae U. Jung, Karin Nielsen-Saines, Frank Xiao-Feng Qin, Cheng-Feng Qin, Zhiheng Xu, Genhong Cheng
Published 2017-10-01

4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues.

by Ewa D Micewicz, Kwanghee Kim, Keisuke S Iwamoto, Josephine A Ratikan, Genhong Cheng, Gayle M Boxx, Robert D Damoiseaux, Julian P Whitelegge, Piotr Ruchala, Christine Nguyen, Prabhat Purbey, Joseph Loo, Gang Deng, Michael E Jung, James W Sayre, Andrew J Norris, Dörthe Schaue, William H McBride
Published 2017-01-01

Interleukin-8 as a Biomarker for Disease Prognosis of Coronavirus Disease-2019 Patients

by Lili Li, Lili Li, Jie Li, Meiling Gao, Meiling Gao, Meiling Gao, Huimin Fan, Huimin Fan, Yanan Wang, Xin Xu, Xin Xu, Chunfeng Chen, Junxiao Liu, Junxiao Liu, Jocelyn Kim, Roghiyh Aliyari, Jicai Zhang, Yujie Jin, Xiaorong Li, Xiaorong Li, Feng Ma, Feng Ma, Minxin Shi, Genhong Cheng, Heng Yang, Heng Yang
Published 2021-01-01

Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection

by Momoko Watanabe, Jessie E. Buth, Neda Vishlaghi, Luis de la Torre-Ubieta, Jiannis Taxidis, Baljit S. Khakh, Giovanni Coppola, Caroline A. Pearson, Ken Yamauchi, Danyang Gong, Xinghong Dai, Robert Damoiseaux, Roghiyh Aliyari, Simone Liebscher, Katja Schenke-Layland, Christine Caneda, Eric J. Huang, Ye Zhang, Genhong Cheng, Daniel H. Geschwind, Peyman Golshani, Ren Sun, Bennett G. Novitch
Published 2017-10-01

Zika virus vertical transmission in children with confirmed antenatal exposure

by Patrícia Brasil, Zilton Vasconcelos, Tara Kerin, Claudia Raja Gabaglia, Ieda P. Ribeiro, Myrna C. Bonaldo, Luana Damasceno, Marcos V. Pone, Sheila Pone, Andrea Zin, Irena Tsui, Kristina Adachi, Jose Paulo Pereira, Stephanie L. Gaw, Liege Carvalho, Denise C. Cunha, Leticia Guida, Mirza Rocha, James D. Cherry, Lulan Wang, Saba Aliyari, Genhong Cheng, Suan-Sin Foo, Weiqiang Chen, Jae Jung, Elizabeth Brickley, Maria Elisabeth L. Moreira, Karin Nielsen-Saines
Published 2020-07-01