Enhanced Chondrogenic Capacity of Mesenchymal Stem Cells After TNFα Pre-treatment

by Chantal Voskamp, Wendy J. L. M. Koevoet, Rodrigo A. Somoza, Arnold I. Caplan, Véronique Lefebvre, Gerjo J. V. M. van Osch, Gerjo J. V. M. van Osch, Roberto Narcisi
Published 2020-06-01

Mechanical Stress Inhibits Early Stages of Endogenous Cell Migration: A Pilot Study in an Ex Vivo Osteochondral Model

by Maria L. Vainieri, Mauro Alini, Avner Yayon, Gerjo J. V. M. van Osch, Sibylle Grad
Published 2020-08-01

Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1

by Yannick Nossin, Eric Farrell, Wendy J. L. M. Koevoet, Rodrigo A. Somoza, Rodrigo A. Somoza, Arnold I. Caplan, Arnold I. Caplan, Bent Brachvogel, Bent Brachvogel, Gerjo J. V. M. van Osch, Gerjo J. V. M. van Osch
Published 2020-04-01

Effect of arthritic synovial fluids on the expression of immunomodulatory factors by mesenchymal stem cells: an explorative in-vitro study

by Maarten J.C. Leijs, Gerben M. Van Buul, Gerben M. Van Buul, Erik eLubberts, Pieter K. Bos, Jan A.N. Verhaar, Martin J. Hoogduijn, Gerjo J.V.M. van Osch, Gerjo J.V.M. van Osch
Published 2012-08-01

Long-Term Expansion, Enhanced Chondrogenic Potential, and Suppression of Endochondral Ossification of Adult Human MSCs via WNT Signaling Modulation

by Roberto Narcisi, Mairéad A. Cleary, Pieter A.J. Brama, Martin J. Hoogduijn, Nesrin Tüysüz, Derk ten Berge, Gerjo J.V.M. van Osch
Published 2015-03-01

The synovial fluid from patients with focal cartilage defects contains mesenchymal stem/stromal cells and macrophages with pro- and anti-inflammatory phenotypes

by John Garcia, Charlotte Hulme, Claire Mennan, Sally Roberts, Yvonne M. Bastiaansen-Jenniskens, Gerjo J.V.M. van Osch, Bernhard Tins, Peter Gallacher, Karina Wright
Published 2020-06-01

Association between Oncostatin M Expression and Inflammatory Phenotype in Experimental Arthritis Models and Osteoarthritis Patients

by Joao Pedro Garcia, Lizette Utomo, Imke Rudnik-Jansen, Jie Du, Nicolaas P.A. Zuithoff, Anita Krouwels, Gerjo J.V.M. van Osch, Laura B. Creemers
Published 2021-02-01

Comparing Scaffold-Free and Fibrin-Based Adipose-Derived Stromal Cell Constructs for Adipose Tissue Engineering: An In Vitro and in Vivo Study

by Femke Verseijden, Sandra J. Posthumus-Van Sluijs, Johan W. Van Neck, Stefan O. P. Hofer, Stevan E. R. Hovius, Gerjo J. V. M. Van Osch
Published 2012-10-01

Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo

by Shorouk Fahmy-Garcia, Shorouk Fahmy-Garcia, Eric Farrell, Janneke Witte-Bouma, Iris Robbesom-van den Berge, Melva Suarez, Didem Mumcuoglu, Didem Mumcuoglu, Heike Walles, Sebastiaan G. J. M. Kluijtmans, Bram C. J. van der Eerden, Gerjo J. V. M. van Osch, Gerjo J. V. M. van Osch, Johannes P. T. M. van Leeuwen, Marjolein van Driel
Published 2019-03-01

Prevascular Structures Promote Vascularization in Engineered Human Adipose Tissue Constructs upon Implantation

by Femke Verseijden, Sandra J. Posthumus-Van Sluijs, Eric Farrell, Johan W. Van Neck, Steven E. R. Hovius, Stefan O. P. Hofer, Gerjo J. V. M. Van Osch
Published 2010-08-01

Chondroprotective Actions of Selective COX-2 Inhibitors In Vivo: A Systematic Review

by Ufuk Tan Timur, Marjolein M. J. Caron, Ralph M. Jeuken, Yvonne M. Bastiaansen-Jenniskens, Tim J. M. Welting, Lodewijk W. van Rhijn, Gerjo J. V. M. van Osch, Pieter J. Emans
Published 2020-09-01

Differences in Cartilage-Forming Capacity of Expanded Human Chondrocytes from Ear and Nose and Their Gene Expression Profiles

by Catharine A. Hellingman, Eugène T. P. Verwiel, Inez Slagt, Wendy Koevoet, René M. L. Poublon, Gilbert J. Nolst-Trenité, Robert J. Baatenburg De Jong, Holger Jahr, Gerjo J. V. M. Van Osch
Published 2011-07-01

Bioprinting of a Zonal-Specific Cell Density Scaffold: A Biomimetic Approach for Cartilage Tissue Engineering

by Angeliki Dimaraki, Pedro J. Díaz-Payno, Michelle Minneboo, Mahdiyeh Nouri-Goushki, Maryam Hosseini, Nicole Kops, Roberto Narcisi, Mohammad J. Mirzaali, Gerjo J. V. M. van Osch, Lidy E. Fratila-Apachitei, Amir A. Zadpoor
Published 2021-08-01

Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.

by Laurie M G de Kroon, Roberto Narcisi, Esmeralda N Blaney Davidson, Mairéad A Cleary, Henk M van Beuningen, Wendy J L M Koevoet, Gerjo J V M van Osch, Peter M van der Kraan
Published 2015-01-01

Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger.

by Lobke M Gierman, Benno van El, Frits van der Ham, Angela Koudijs, Reinout Stoop, Jan H Verheijen, Margreet Kloppenburg, Gerjo J V M van Osch, Vedrana Stojanovic-Susulic, Tom W J Huizinga, Anne-Marie Zuurmond
Published 2013-01-01

Clinically translatable cell tracking and quantification by MRI in cartilage repair using superparamagnetic iron oxides.

by Gerben M van Buul, Gyula Kotek, Piotr A Wielopolski, Eric Farrell, P Koen Bos, Harrie Weinans, Anja U Grohnert, Holger Jahr, Jan A N Verhaar, Gabriel P Krestin, Gerjo J V M van Osch, Monique R Bernsen
Published 2011-01-01

Lack of high BMI-related features in adipocytes and inflammatory cells in the infrapatellar fat pad (IFP)

by Anja J. de Jong, Inge R. Klein-Wieringa, Stefan N. Andersen, Joanneke C. Kwekkeboom, Linda Herb-van Toorn, Badelog J. E. de Lange-Brokaar, Danny van Delft, John Garcia, Wu Wei, Huub J. L. van der Heide, Yvonne M. Bastiaansen-Jenniskens, Gerjo J. V. M. van Osch, Annemarie M. Zuurmond, Vedrana Stojanovic-Susulic, Rob G. H. H. Nelissen, René E. M. Toes, Margreet Kloppenburg, Andreea Ioan-Facsinay
Published 2017-08-01