Transcription Factors in Cartilage Homeostasis and Osteoarthritis

by Margot Neefjes, Arjan P.M. van Caam, Peter M. van der Kraan
Published 2020-09-01

TGFβ/BMP Signaling Pathway in Cartilage Homeostasis

by Nathalie G.M. Thielen, Peter M. van der Kraan, Arjan P.M. van Caam
Published 2019-08-01

Systemic Resolvin E1 (RvE1) Treatment Does Not Ameliorate the Severity of Collagen-Induced Arthritis (CIA) in Mice: A Randomized, Prospective, and Controlled Proof of Concept Study

by Rafael Scaf de Molon, Rogier M. Thurlings, Birgitte Walgreen, Monique M. Helsen, Peter M. van der Kraan, Joni Augusto Cirelli, Marije I. Koenders
Published 2019-01-01

Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis.

by Claire E J Waterborg, Marije I Koenders, Peter L E M van Lent, Peter M van der Kraan, Fons A J van de Loo
Published 2018-01-01

An optimized method for plasma extracellular vesicles isolation to exclude the copresence of biological drugs and plasma proteins which impairs their biological characterization.

by Onno J Arntz, Bartijn C H Pieters, Peter L E M van Lent, Marije I Koenders, Peter M van der Kraan, Fons A J van de Loo
Published 2020-01-01

Hit hard and early: analysing the effects of high-dose methylprednisolone on nailfold capillary changes and biomarkers in very early systemic sclerosis: study protocol for a 12-wee...

by Wieneke M. T. van den Hombergh, Brigit E. Kersten, Hanneke K. A. Knaapen-Hans, Rogier M. Thurlings, Peter M. van der Kraan, Frank H. J. van den Hoogen, Jaap Fransen, Madelon C. Vonk
Published 2018-08-01

Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium.

by Mathijs G A Broeren, Marieke de Vries, Miranda B Bennink, Peter L E M van Lent, Peter M van der Kraan, Marije I Koenders, Rogier M Thurlings, Fons A J van de Loo
Published 2016-01-01

Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.

by Laurie M G de Kroon, Roberto Narcisi, Esmeralda N Blaney Davidson, Mairéad A Cleary, Henk M van Beuningen, Wendy J L M Koevoet, Gerjo J V M van Osch, Peter M van der Kraan
Published 2015-01-01

The alarmins S100A8 and S100A9 mediate acute pain in experimental synovitis

by Arjen B. Blom, Martijn H. van den Bosch, Esmeralda N. Blaney Davidson, Johannes Roth, Thomas Vogl, Fons A. van de Loo, Marije Koenders, Peter M. van der Kraan, Edwin J. Geven, Peter L. van Lent
Published 2020-08-01

Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis

by Julia Vullings, Juliana P. Vago, Claire E. J. Waterborg, Rogier M. Thurlings, Marije I. Koenders, Peter L. E. M. van Lent, Peter M. van der Kraan, Flavio A. Amaral, Fons A. J. van de Loo
Published 2020-01-01

Higher efficacy of anti-IL-6/IL-21 combination therapy compared to monotherapy in the induction phase of Th17-driven experimental arthritis.

by Debbie M Roeleveld, Renoud J Marijnissen, Birgitte Walgreen, Monique M Helsen, Liduine van den Bersselaar, Fons A van de Loo, Peter L van Lent, Peter M van der Kraan, Wim B van den Berg, Marije I Koenders
Published 2017-01-01

Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models

by Claire E. J. Waterborg, Silke Beermann, Mathijs G. A. Broeren, Miranda B. Bennink, Marije I. Koenders, Peter L. E. M. van Lent, Wim B. van den Berg, Peter M. van der Kraan, Fons A. J. van de Loo
Published 2018-04-01

Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation

by Mathijs G.A. Broeren, Irene Di Ceglie, Miranda B. Bennink, Peter L.E.M. van Lent, Wim B. van den Berg, Marije I. Koenders, Esmeralda N. Blaney Davidson, Peter M. van der Kraan, Fons A.J. van de Loo
Published 2018-05-01

Rheumatoid Arthritis Patients With Circulating Extracellular Vesicles Positive for IgM Rheumatoid Factor Have Higher Disease Activity

by Onno J. Arntz, Bartijn C. H. Pieters, Rogier M. Thurlings, Mark H. Wenink, Peter L. E. M. van Lent, Marije I. Koenders, Frank H. J. van den Hoogen, Frank H. J. van den Hoogen, Peter M. van der Kraan, Fons A. J. van de Loo
Published 2018-10-01

Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency promotes IL-17- and TLR4-dependent arthritis

by Rebecca Rogier, Thomas H. A. Ederveen, Jos Boekhorst, Harm Wopereis, Jose U. Scher, Julia Manasson, Sanne J. C. M. Frambach, Jan Knol, Johan Garssen, Peter M. van der Kraan, Marije I. Koenders, Wim B. van den Berg, Sacha A. F. T. van Hijum, Shahla Abdollahi-Roodsaz
Published 2017-06-01

Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β.

by Bartijn C H Pieters, Onno J Arntz, Miranda B Bennink, Mathijs G A Broeren, Arjan P M van Caam, Marije I Koenders, Peter L E M van Lent, Wim B van den Berg, Marieke de Vries, Peter M van der Kraan, Fons A J van de Loo
Published 2015-01-01

Correction: Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice...

by Rebecca Rogier, Thomas H A Ederveen, Harm Wopereis, Anita Hartog, Jos Boekhorst, Sacha A F T van Hijum, Jan Knol, Johan Garssen, Birgitte Walgreen, Monique M Helsen, Peter M van der Kraan, Peter L E M van Lent, Fons A J van de Loo, Shahla Abdollahi-Roodsaz, Marije I Koenders
Published 2019-01-01

Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice.

by Rebecca Rogier, Thomas H A Ederveen, Harm Wopereis, Anita Hartog, Jos Boekhorst, Sacha A F T van Hijum, Jan Knol, Johan Garssen, Birgitte Walgreen, Monique M Helsen, Peter M van der Kraan, Peter L E M van Lent, Fons A J van de Loo, Shahla Abdollahi-Roodsaz, Marije I Koenders
Published 2019-01-01

Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis

by Irene Di Ceglie, Giuliana Ascone, Niels A. J. Cremers, Annet W. Sloetjes, Birgitte Walgreen, Thomas Vogl, Johannes Roth, J. Sjef Verbeek, Fons A. J. van de Loo, Marije I. Koenders, Peter M. van der Kraan, Arjen B. Blom, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Published 2018-05-01

IL-1β-Mediated Activation of Adipose-Derived Mesenchymal Stromal Cells Results in PMN Reallocation and Enhanced Phagocytosis: A Possible Mechanism for the Reduction of Osteoarthrit...

by Stephanie C. M. van Dalen, Arjen B. Blom, Birgitte Walgreen, Annet W. Slöetjes, Monique M. A. Helsen, Edwin J. W. Geven, Menno ter Huurne, Thomas Vogl, Johannes Roth, Fons A. J. van de Loo, Marije I. Koenders, Louis Casteilla, Peter M. van der Kraan, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Published 2019-05-01