Therapeutic Potential for Regulation of the Nuclear Factor Kappa-B Transcription Factor p65 to Prevent Cellular Senescence and Activation of Pro-Inflammatory in Mesenchymal Stem Ce...

by Rocío Mato-Basalo, Miriam Morente-López, Onno J Arntz, Fons A. J. van de Loo, Juan Fafián-Labora, María C. Arufe
Published 2021-03-01

Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis.

by Claire E J Waterborg, Marije I Koenders, Peter L E M van Lent, Peter M van der Kraan, Fons A J van de Loo
Published 2018-01-01

A tail-anchored myotonic dystrophy protein kinase isoform induces perinuclear clustering of mitochondria, autophagy, and apoptosis.

by Ralph J A Oude Ophuis, Mietske Wijers, Miranda B Bennink, Fons A J van de Loo, Jack A M Fransen, Bé Wieringa, Derick G Wansink
Published 2009-11-01

Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing

by Juan Fafián-Labora, Miriam Morente-López, María José Sánchez-Dopico, Onno J. Arntz, Fons A. J. van de Loo, Javier De Toro, María C. Arufe
Published 2020-01-01

Macrophage-Derived Extracellular Vesicles as Carriers of Alarmins and Their Potential Involvement in Bone Homeostasis

by Bartijn C. H. Pieters, Alfredo Cappariello, Martijn H. J. van den Bosch, Peter L. E. M. van Lent, Anna Teti, Fons A. J. van de Loo
Published 2019-08-01

An optimized method for plasma extracellular vesicles isolation to exclude the copresence of biological drugs and plasma proteins which impairs their biological characterization.

by Onno J Arntz, Bartijn C H Pieters, Peter L E M van Lent, Marije I Koenders, Peter M van der Kraan, Fons A J van de Loo
Published 2020-01-01

Intravenous delivery of HIV-based lentiviral vectors preferentially transduces F4/80+ and Ly-6C+ cells in spleen, important target cells in autoimmune arthritis.

by Ben T van den Brand, Eline A Vermeij, Claire E J Waterborg, Onno J Arntz, Michael Kracht, Miranda B Bennink, Wim B van den Berg, Fons A J van de Loo
Published 2013-01-01

In Vivo Molecular Imaging of Cathepsin and Matrix Metalloproteinase Activity Discriminates between Arthritic and Osteoarthritic Processes in Mice

by Eline A. Vermeij, Marije I. Koenders, Arjen B. Blom, Onno J. Arntz, Miranda B. Bennink, Wim B. van den Berg, Peter L.E.M. van Lent, Fons A.J. van de Loo
Published 2014-01-01

Functional Tissue Analysis Reveals Successful Cryopreservation of Human Osteoarthritic Synovium.

by Mathijs G A Broeren, Marieke de Vries, Miranda B Bennink, Peter L E M van Lent, Peter M van der Kraan, Marije I Koenders, Rogier M Thurlings, Fons A J van de Loo
Published 2016-01-01

Selective Increment of Synovial Soluble TYRO3 Correlates with Disease Severity and Joint Inflammation in Patients with Rheumatoid Arthritis

by Julia Vullings, Juliana P. Vago, Claire E. J. Waterborg, Rogier M. Thurlings, Marije I. Koenders, Peter L. E. M. van Lent, Peter M. van der Kraan, Flavio A. Amaral, Fons A. J. van de Loo
Published 2020-01-01

The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis.

by Eline A Vermeij, Marije I Koenders, Miranda B Bennink, Lindsey A Crowe, Lionel Maurizi, Jean-Paul Vallée, Heinrich Hofmann, Wim B van den Berg, Peter L E M van Lent, Fons A J van de Loo
Published 2015-01-01

Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models

by Claire E. J. Waterborg, Silke Beermann, Mathijs G. A. Broeren, Miranda B. Bennink, Marije I. Koenders, Peter L. E. M. van Lent, Wim B. van den Berg, Peter M. van der Kraan, Fons A. J. van de Loo
Published 2018-04-01

Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation

by Mathijs G.A. Broeren, Irene Di Ceglie, Miranda B. Bennink, Peter L.E.M. van Lent, Wim B. van den Berg, Marije I. Koenders, Esmeralda N. Blaney Davidson, Peter M. van der Kraan, Fons A.J. van de Loo
Published 2018-05-01

Flood Control: How Milk-Derived Extracellular Vesicles Can Help to Improve the Intestinal Barrier Function and Break the Gut–Joint Axis in Rheumatoid Arthritis

by Joyce Aarts, Annemarie Boleij, Bartijn C. H. Pieters, Anouk L. Feitsma, R. J. Joost van Neerven, R. J. Joost van Neerven, Jean Paul ten Klooster, Laura M’Rabet, Onno J. Arntz, Marije I. Koenders, Fons A. J. van de Loo
Published 2021-07-01

Tumor Necrosis Factor, but Not Neutrophils, Alters the Metabolic Profile in Acute Experimental Arthritis.

by Marina C Oliveira, Luciana P Tavares, Juliana P Vago, Nathália V Batista, Celso M Queiroz-Junior, Angelica T Vieira, Gustavo B Menezes, Lirlândia P Sousa, Fons A J van de Loo, Mauro M Teixeira, Flávio A Amaral, Adaliene V M Ferreira
Published 2016-01-01

Rheumatoid Arthritis Patients With Circulating Extracellular Vesicles Positive for IgM Rheumatoid Factor Have Higher Disease Activity

by Onno J. Arntz, Bartijn C. H. Pieters, Rogier M. Thurlings, Mark H. Wenink, Peter L. E. M. van Lent, Marije I. Koenders, Frank H. J. van den Hoogen, Frank H. J. van den Hoogen, Peter M. van der Kraan, Fons A. J. van de Loo
Published 2018-10-01

Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β.

by Bartijn C H Pieters, Onno J Arntz, Miranda B Bennink, Mathijs G A Broeren, Arjan P M van Caam, Marije I Koenders, Peter L E M van Lent, Wim B van den Berg, Marieke de Vries, Peter M van der Kraan, Fons A J van de Loo
Published 2015-01-01

Correction: Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice...

by Rebecca Rogier, Thomas H A Ederveen, Harm Wopereis, Anita Hartog, Jos Boekhorst, Sacha A F T van Hijum, Jan Knol, Johan Garssen, Birgitte Walgreen, Monique M Helsen, Peter M van der Kraan, Peter L E M van Lent, Fons A J van de Loo, Shahla Abdollahi-Roodsaz, Marije I Koenders
Published 2019-01-01

Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice.

by Rebecca Rogier, Thomas H A Ederveen, Harm Wopereis, Anita Hartog, Jos Boekhorst, Sacha A F T van Hijum, Jan Knol, Johan Garssen, Birgitte Walgreen, Monique M Helsen, Peter M van der Kraan, Peter L E M van Lent, Fons A J van de Loo, Shahla Abdollahi-Roodsaz, Marije I Koenders
Published 2019-01-01

Fcγ receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis

by Irene Di Ceglie, Giuliana Ascone, Niels A. J. Cremers, Annet W. Sloetjes, Birgitte Walgreen, Thomas Vogl, Johannes Roth, J. Sjef Verbeek, Fons A. J. van de Loo, Marije I. Koenders, Peter M. van der Kraan, Arjen B. Blom, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Published 2018-05-01