Chromatin Targeting of HIPK2 Leads to Acetylation-Dependent Chromatin Decondensation

by Jana Haas, Jana Haas, Daniel Bloesel, Daniel Bloesel, Susanne Bacher, Susanne Bacher, Michael Kracht, Michael Kracht, M. Lienhard Schmitz, M. Lienhard Schmitz
Published 2020-09-01

Regulation of Transcription Factor NF-κB in Its Natural Habitat: The Nucleus

by Susanne Bacher, Johanna Meier-Soelch, Michael Kracht, M. Lienhard Schmitz
Published 2021-03-01

The Crosstalk of Endoplasmic Reticulum (ER) Stress Pathways with NF-κB: Complex Mechanisms Relevant for Cancer, Inflammation and Infection

by M. Lienhard Schmitz, M. Samer Shaban, B. Vincent Albert, Anke Gökçen, Michael Kracht
Published 2018-05-01

ULK1/2 Restricts the Formation of Inducible SINT-Speckles, Membraneless Organelles Controlling the Threshold of TBK1 Activation

by Vera Vivian Saul, Markus Seibert, Marcus Krüger, Sylvia Jeratsch, Michael Kracht, Michael Lienhard Schmitz
Published 2019-09-01

The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice

by Tabea Riedlinger, Jana Haas, Julia Busch, Bart van de Sluis, Michael Kracht, M. Lienhard Schmitz
Published 2018-03-01

Dynamic mRNP Remodeling in Response to Internal and External Stimuli

by Kathi Zarnack, Sureshkumar Balasubramanian, Michael P. Gantier, Vladislav Kunetsky, Michael Kracht, M. Lienhard Schmitz, Katja Sträßer
Published 2020-09-01

Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1.

by Alexander Wolf, Knut Beuerlein, Christoph Eckart, Hendrik Weiser, Beate Dickkopf, Helmut Müller, Hiroaki Sakurai, Michael Kracht
Published 2011-01-01

Single-Cell Analysis of Multiple Steps of Dynamic NF-κB Regulation in Interleukin-1α-Triggered Tumor Cells Using Proximity Ligation Assays

by Christin Mayr-Buro, Eva Schlereth, Knut Beuerlein, Ulas Tenekeci, Johanna Meier-Soelch, M. Lienhard Schmitz, Michael Kracht
Published 2019-08-01

Chemotherapeutic Drugs Inhibiting Topoisomerase 1 Activity Impede Cytokine-Induced and NF-κB p65-Regulated Gene Expression

by Tabea Riedlinger, Marek Bartkuhn, Tobias Zimmermann, Sandra B. Hake, Andrea Nist, Thorsten Stiewe, Michael Kracht, M. Lienhard Schmitz
Published 2019-06-01

RNAi-Based Identification of Gene-Specific Nuclear Cofactor Networks Regulating Interleukin-1 Target Genes

by Johanna Meier-Soelch, Liane Jurida, Axel Weber, Doris Newel, Johnny Kim, Thomas Braun, M. Lienhard Schmitz, Michael Kracht
Published 2018-04-01

Regulation of TAK1/TAB1-mediated IL-1β signaling by cytoplasmic PPARβ/δ.

by Josefine Stockert, Alexander Wolf, Kerstin Kaddatz, Evelyn Schnitzer, Florian Finkernagel, Wolfgang Meissner, Sabine Müller-Brüsselbach, Michael Kracht, Rolf Müller
Published 2013-01-01

CTRP9 Mediates Protective Effects in Cardiomyocytes via AMPK- and Adiponectin Receptor-Mediated Induction of Anti-Oxidant Response

by Bernd Niemann, Ling Li, Dorothee Siegler, Benedikt H. Siegler, Fabienne Knapp, Jakob Hanna, Muhammad Aslam, Michael Kracht, Rainer Schulz, Susanne Rohrbach
Published 2020-05-01

The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription

by Alfonso Rodríguez-Gil, Olesja Ritter, Vera V. Saul, Jochen Wilhelm, Chen-Yuan Yang, Rudolf Grosschedl, Yumiko Imai, Keiji Kuba, Michael Kracht, M. Lienhard Schmitz
Published 2017-06-01

The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells.

by Michael Poppe, Sascha Wittig, Liane Jurida, Marek Bartkuhn, Jochen Wilhelm, Helmut Müller, Knut Beuerlein, Nadja Karl, Sabin Bhuju, John Ziebuhr, M Lienhard Schmitz, Michael Kracht
Published 2017-03-01

Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression.

by Holger Buss, Katja Handschick, Nadine Jurrmann, Pirita Pekkonen, Knut Beuerlein, Helmut Müller, Robin Wait, Jeremy Saklatvala, Päivi M Ojala, M Lienhard Schmitz, Michael Naumann, Michael Kracht
Published 2012-01-01

Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression.

by Kiran Bala, Raffaella Bosco, Silvia Gramolelli, Darya A Haas, Semra Kati, Marcel Pietrek, Anika Hävemeier, Yuri Yakushko, Vivek Vikram Singh, Oliver Dittrich-Breiholz, Michael Kracht, Thomas F Schulz
Published 2012-09-01

The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB p65

by Liane Jurida, Johanna Soelch, Marek Bartkuhn, Katja Handschick, Helmut Müller, Doris Newel, Axel Weber, Oliver Dittrich-Breiholz, Heike Schneider, Sabin Bhuju, Vera V. Saul, M. Lienhard Schmitz, Michael Kracht
Published 2015-02-01

TRAF6 Phosphorylation Prevents Its Autophagic Degradation and Re-Shapes LPS-Triggered Signaling Networks

by Julia Busch, Rita Moreno, Laureano de la Vega, Vera Vivian Saul, Susanne Bacher, Felix von Zweydorf, Marius Ueffing, Axel Weber, Christian Johannes Gloeckner, Uwe Linne, Michael Kracht, Michael Lienhard Schmitz
Published 2021-07-01

Intravenous delivery of HIV-based lentiviral vectors preferentially transduces F4/80+ and Ly-6C+ cells in spleen, important target cells in autoimmune arthritis.

by Ben T van den Brand, Eline A Vermeij, Claire E J Waterborg, Onno J Arntz, Michael Kracht, Miranda B Bennink, Wim B van den Berg, Fons A J van de Loo
Published 2013-01-01

The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells.

by Darya A Haas, Kiran Bala, Guntram Büsche, Magdalena Weidner-Glunde, Susann Santag, Semra Kati, Silvia Gramolelli, Modester Damas, Oliver Dittrich-Breiholz, Michael Kracht, Jessica Rückert, Zoltan Varga, György Keri, Thomas F Schulz
Published 2013-01-01