Diagnostic and prognostic value of SHOX2 and SEPT9 DNA methylation and cytology in benign, paramalignant and malignant pleural effusions.

by Dimo Dietrich, Maria Jung, Svenja Puetzer, Annette Leisse, Emily Eva Holmes, Sebastian Meller, Barbara Uhl, Philipp Schatz, Claudia Ivascu, Glen Kristiansen
Published 2013-01-01

Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development.

by Daniel Nettersheim, Lukas C Heukamp, Florian Fronhoffs, Marc J Grewe, Natalie Haas, Anke Waha, Friedemann Honecker, Andreas Waha, Glen Kristiansen, Hubert Schorle
Published 2013-01-01

<i>miR-449a</i> Repression Leads to Enhanced NOTCH Signaling in <i>TMPRSS2:ERG</i> Fusion Positive Prostate Cancer Cells

by Simone Bauer, Leonie Ratz, Doreen Heckmann-Nötzel, Adam Kaczorowski, Markus Hohenfellner, Glen Kristiansen, Stefan Duensing, Peter Altevogt, Sabine M. Klauck, Holger Sültmann
Published 2021-02-01

BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma.

by Daniel Nettersheim, Sina Jostes, Rakesh Sharma, Simon Schneider, Andrea Hofmann, Humberto J Ferreira, Per Hoffmann, Glen Kristiansen, Manel B Esteller, Hubert Schorle
Published 2015-07-01

Hereditary Diffuse Gastric Cancer: A Comparative Cohort Study According to Pathogenic Variant Status

by Tim Marwitz, Robert Hüneburg, Isabel Spier, Jan-Frederic Lau, Glen Kristiansen, Philipp Lingohr, Jörg C. Kalff, Stefan Aretz, Jacob Nattermann, Christian P. Strassburg
Published 2020-12-01

Downstream Neighbor of SON (DONSON) Expression Is Enhanced in Phenotypically Aggressive Prostate Cancers

by Niklas Klümper, Marthe von Danwitz, Johannes Stein, Doris Schmidt, Anja Schmidt, Glen Kristiansen, Michael Muders, Michael Hölzel, Manuel Ritter, Abdullah Alajati, Jörg Ellinger
Published 2020-11-01

Performance evaluation of kits for bisulfite-conversion of DNA from tissues, cell lines, FFPE tissues, aspirates, lavages, effusions, plasma, serum, and urine.

by Emily Eva Holmes, Maria Jung, Sebastian Meller, Annette Leisse, Verena Sailer, Julie Zech, Martina Mengdehl, Leif-Alexander Garbe, Barbara Uhl, Glen Kristiansen, Dimo Dietrich
Published 2014-01-01

Implication of the Receptor Tyrosine Kinase AXL in Head and Neck Cancer Progression

by Anne von Mässenhausen, Johannes Brägelmann, Hannah Billig, Britta Thewes, Angela Queisser, Wenzel Vogel, Glen Kristiansen, Andreas Schröck, Friedrich Bootz, Peter Brossart, Jutta Kirfel, Sven Perner
Published 2016-12-01

DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract.

by Barbara Uhl, Dimo Dietrich, Vittorio Branchi, Alexander Semaan, Pauline Schaefer, Heidrun Gevensleben, Babak Rostamzadeh, Philipp Lingohr, Nico Schäfer, Jörg C Kalff, Glen Kristiansen, Hanno Matthaei
Published 2016-01-01

Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer.

by Andreas Schröck, Friederike Göke, Patrick Wagner, Maike Bode, Alina Franzen, Martin Braun, Sebastian Huss, Abbas Agaimy, Stephan Ihrler, Ropika Menon, Robert Kirsten, Glen Kristiansen, Friedrich Bootz, Claudia Lengerke, Sven Perner
Published 2013-01-01

Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer

by Tristan Lerbs, Savita Bisht, Sebastian Schölch, Mathieu Pecqueux, Glen Kristiansen, Martin Schneider, Bianca T. Hofmann, Thilo Welsch, Christoph Reissfelder, Nuh N. Rahbari, Johannes Fritzmann, Peter Brossart, Jürgen Weitz, Georg Feldmann, Christoph Kahlert
Published 2017-04-01

Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats

by Carla Cremonese, Robert Schierwagen, Frank Erhard Uschner, Sandra Torres, Olaf Tyc, Cristina Ortiz, Martin Schulz, Alexander Queck, Glen Kristiansen, Michael Bader, Tilman Sauerbruch, Ralf Weiskirchen, Thomas Walther, Jonel Trebicka, Sabine Klein ¹
Published 2020-05-01

Cultivation of Clear Cell Renal Cell Carcinoma Patient-Derived Organoids in an Air-Liquid Interface System as a Tool for Studying Individualized Therapy

by Laura K. Esser, Vittorio Branchi, Sonia Leonardelli, Natalie Pelusi, Adrian G. Simon, Niklas Klümper, Jörg Ellinger, Stefan Hauser, Maria A. Gonzalez-Carmona, Manuel Ritter, Glen Kristiansen, Hubert Schorle, Michael Hölzel, Marieta I. Toma
Published 2020-09-01

Tumor Infiltrating Neutrophils Are Frequently Found in Adenocarcinomas of the Biliary Tract and Their Precursor Lesions with Possible Impact on Prognosis

by Vittorio Branchi, Benedict Jürgensen, Laura Esser, Maria Gonzalez-Carmona, Tobias J. Weismüller, Christian P. Strassburg, Jonas Henn, Alexander Semaan, Philipp Lingohr, Steffen Manekeller, Glen Kristiansen, Jörg C. Kalff, Marieta I. Toma, Hanno Matthaei
Published 2021-03-01

Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response...

by Anne Fröhlich, Sophia Loick, Emma Grace Bawden, Simon Fietz, Jörn Dietrich, Eric Diekmann, Gonzalo Saavedra, Holger Fröhlich, Dennis Niebel, Judith Sirokay, Romina Zarbl, Gerrit H. Gielen, Glen Kristiansen, Friedrich Bootz, Jennifer Landsberg, Dimo Dietrich
Published 2020-02-01

MAGE-C2/CT10 protein expression is an independent predictor of recurrence in prostate cancer.

by Lotta von Boehmer, Lukas Keller, Ashkan Mortezavi, Maurizio Provenzano, Giovanni Sais, Thomas Hermanns, Tullio Sulser, Achim A Jungbluth, Lloyd J Old, Glen Kristiansen, Maries van den Broek, Holger Moch, Alexander Knuth, Peter J Wild
Published 2011-01-01

Identification and Validation of Potential New Biomarkers for Prostate Cancer Diagnosis and Prognosis Using 2D-DIGE and MS

by Cordelia Geisler, Nadine T. Gaisa, David Pfister, Susanne Fuessel, Glen Kristiansen, Till Braunschweig, Sonja Gostek, Birte Beine, Hanna C. Diehl, Angela M. Jackson, Christoph H. Borchers, Axel Heidenreich, Helmut E. Meyer, Ruth Knüchel, Corinna Henkel
Published 2015-01-01

Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS)

by Sukanya Horpaopan, Jutta Kirfel, Sophia Peters, Michael Kloth, Robert Hüneburg, Janine Altmüller, Dmitriy Drichel, Margarete Odenthal, Glen Kristiansen, Christian Strassburg, Jacob Nattermann, Per Hoffmann, Peter Nürnberg, Reinhard Büttner, Holger Thiele, Philip Kahl, Isabel Spier, Stefan Aretz
Published 2017-11-01

DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients’ survival, immune cell infil...

by Verena Sailer, Ulrike Sailer, Emma Grace Bawden, Romina Zarbl, Constanze Wiek, Timo J. Vogt, Joern Dietrich, Sophia Loick, Ingela Grünwald, Marieta Toma, Carsten Golletz, Andreas Gerstner, Glen Kristiansen, Friedrich Bootz, Kathrin Scheckenbach, Jennifer Landsberg, Dimo Dietrich
Published 2019-10-01

A Combined TLR7/TLR9/GATA3 Score Can Predict Prognosis in Biliary Tract Cancer

by Vittorio Branchi, Laura Esser, Corinna Boden, Azin Jafari, Jonas Henn, Philipp Lingohr, Maria A. Gonzalez-Carmona, Marc Schmitz, Tobias J. Weismüller, Christian P. Strassburg, Steffen Manekeller, Glen Kristiansen, Jörg C. Kalff, Hanno Matthaei, Marieta I. Toma
Published 2021-09-01