Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C.

by Bettina Langhans, Hans Dieter Nischalke, Simone Arndt, Ingrid Braunschweiger, Jacob Nattermann, Tilman Sauerbruch, Ulrich Spengler
Published 2012-01-01

Semiquantitative analysis of intrahepatic CC-chemokine mRNAs in chronic hepatitis C

by Franz Ludwig Dumoulin, Ulrich Spengler, Tilman Sauerbruch, Hans-Peter Fischer, Hans Dieter Nischalke, Jacob Nattermann
Published 2004-01-01

Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis.

by Henning W Zimmermann, Sebastian Seidler, Nikolaus Gassler, Jacob Nattermann, Tom Luedde, Christian Trautwein, Frank Tacke
Published 2011-01-01

Detection of IGF2BP3, HOXB7, and NEK2 mRNA expression in brush cytology specimens as a new diagnostic tool in patients with biliary strictures.

by Hans Dieter Nischalke, Volker Schmitz, Carolin Luda, Katharina Aldenhoff, Cordula Berger, Georg Feldmann, Tilman Sauerbruch, Ulrich Spengler, Jacob Nattermann
Published 2012-01-01

NK Cells in Ascites From Liver Disease Patients Display a Particular Phenotype and Take Part in Antibacterial Immune Response

by Philipp Lutz, Philipp Lutz, Philipp Lutz, Hannah C. Jeffery, Nicholas Jones, Jane Birtwistle, Benjamin Kramer, Benjamin Kramer, Jacob Nattermann, Jacob Nattermann, Ulrich Spengler, Ulrich Spengler, Christian P. Strassburg, Christian P. Strassburg, David H. Adams, David H. Adams, Ye H. Oo, Ye H. Oo
Published 2019-08-01

The CXCR3(+)CD56Bright phenotype characterizes a distinct NK cell subset with anti-fibrotic potential that shows dys-regulated activity in hepatitis C.

by Marianne Eisenhardt, Andreas Glässner, Benjamin Krämer, Christian Körner, Bernhard Sibbing, Pavlos Kokordelis, Hans Dieter Nischalke, Tilman Sauerbruch, Ulrich Spengler, Jacob Nattermann
Published 2012-01-01

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites.

by Philipp Lutz, Marijo Parcina, Isabelle Bekeredjian-Ding, Hans Dieter Nischalke, Jacob Nattermann, Tilman Sauerbruch, Achim Hoerauf, Christian P Strassburg, Ulrich Spengler
Published 2014-01-01

Colonoscopy detects significantly more flat adenomas than 3-tesla magnetic resonance colonography: a pilot trial

by Robert Hüneburg, Guido Kukuk, Jacob Nattermann, Christoph Endler, Arndt-Hendrik Penner, Karsten Wolter, Hans Schild, Christian Strassburg, Tilman Sauerbruch, Volker Schmitz, Winfried Willinek
Published 2016-01-01

Hereditary Diffuse Gastric Cancer: A Comparative Cohort Study According to Pathogenic Variant Status

by Tim Marwitz, Robert Hüneburg, Isabel Spier, Jan-Frederic Lau, Glen Kristiansen, Philipp Lingohr, Jörg C. Kalff, Stefan Aretz, Jacob Nattermann, Christian P. Strassburg
Published 2020-12-01

Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis.

by Henning W Zimmermann, Sebastian Seidler, Jacob Nattermann, Nikolaus Gassler, Claus Hellerbrand, Alma Zernecke, Jens J W Tischendorf, Tom Luedde, Ralf Weiskirchen, Christian Trautwein, Frank Tacke
Published 2010-06-01

IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C.

by Benjamin Krämer, Claudia Finnemann, Beatriz Sastre, Philipp Lutz, Andreas Glässner, Franziska Wolter, Felix Goeser, Pavlos Kokordelis, Dominik Kaczmarek, Hans-Dieter Nischalke, Christian P Strassburg, Ulrich Spengler, Jacob Nattermann
Published 2016-01-01

Chromoendoscopy in combination with random biopsies does not improve detection of gastric cancer foci in CDH1 mutation positive patients

by Robert Hüneburg, Tim Marwitz, Peer van Heteren, Tobias J. Weismüller, Jonel Trebicka, Ronja Adam, Stefan Aretz, Alberto Perez Bouza, Dimitrios Pantelis, Jörg C. Kalff, Jacob Nattermann, Cristian P. Strassburg
Published 2016-08-01

Alterations of the NK cell pool in HIV/HCV co-infection.

by Dominik J Kaczmarek, Pavlos Kokordelis, Benjamin Krämer, Andreas Glässner, Franziska Wolter, Felix Goeser, Philipp Lutz, Carolynne Schwarze-Zander, Christoph Boesecke, Christian P Strassburg, Jürgen K Rockstroh, Ulrich Spengler, Jacob Nattermann
Published 2017-01-01

The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.

by Hans Dieter Nischalke, Cordula Berger, Carolin Luda, Thomas Berg, Tobias Müller, Frank Grünhage, Frank Lammert, Martin Coenen, Benjamin Krämer, Christian Körner, Natascha Vidovic, Johannes Oldenburg, Jacob Nattermann, Tilman Sauerbruch, Ulrich Spengler
Published 2011-01-01

Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS)

by Sukanya Horpaopan, Jutta Kirfel, Sophia Peters, Michael Kloth, Robert Hüneburg, Janine Altmüller, Dmitriy Drichel, Margarete Odenthal, Glen Kristiansen, Christian Strassburg, Jacob Nattermann, Per Hoffmann, Peter Nürnberg, Reinhard Büttner, Holger Thiele, Philip Kahl, Isabel Spier, Stefan Aretz
Published 2017-11-01

Compartment-specific distribution of human intestinal innate lymphoid cells is altered in HIV patients under effective therapy.

by Benjamin Krämer, Felix Goeser, Philipp Lutz, Andreas Glässner, Christoph Boesecke, Carolynne Schwarze-Zander, Dominik Kaczmarek, Hans Dieter Nischalke, Vittorio Branchi, Steffen Manekeller, Robert Hüneburg, Tobias van Bremen, Tobias Weismüller, Christian P Strassburg, Jürgen K Rockstroh, Ulrich Spengler, Jacob Nattermann
Published 2017-05-01

Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent.

by Hans Dieter Nischalke, Cordula Berger, Philipp Lutz, Bettina Langhans, Franziska Wolter, Marianne Eisenhardt, Benjamin Krämer, Pavlos Kokordelis, Andreas Glässner, Tobias Müller, Jonas Rosendahl, Janett Fischer, Thomas Berg, Frank Grünhage, Ludger Leifeld, Michael Soyka, Jacob Nattermann, Tilman Sauerbruch, Felix Stickel, Ulrich Spengler
Published 2013-01-01

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity

by Nicolas Huot, Philippe Rascle, Caroline Petitdemange, Vanessa Contreras, Christina M. Stürzel, Eduard Baquero, Justin L. Harper, Caroline Passaes, Rachel Legendre, Hugo Varet, Yoann Madec, Ulrike Sauermann, Christiane Stahl-Hennig, Jacob Nattermann, Asier Saez-Cirion, Roger Le Grand, R. Keith Reeves, Mirko Paiardini, Frank Kirchhoff, Beatrice Jacquelin, Michaela Müller-Trutwin
Published 2021-02-01

Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study

by Karolin Bucksch, Silke Zachariae, Stefan Aretz, Reinhard Büttner, Elke Holinski-Feder, Stefanie Holzapfel, Robert Hüneburg, Matthias Kloor, Magnus von Knebel Doeberitz, Monika Morak, Gabriela Möslein, Jacob Nattermann, Claudia Perne, Nils Rahner, Wolff Schmiegel, Karsten Schulmann, Verena Steinke-Lange, Christian P. Strassburg, Deepak B. Vangala, Jürgen Weitz, Markus Loeffler, Christoph Engel, on behalf of the German Consortium for Familial Intestinal Cancer
Published 2020-05-01

N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection

by Dandan Shan, Joseph M. Johnson, Syrena C. Fernandes, Hannah Suib, Soyoon Hwang, Danica Wuelfing, Muriel Mendes, Marcella Holdridge, Elaine M. Burke, Katie Beauregard, Ying Zhang, Megan Cleary, Samantha Xu, Xiao Yao, Purvish P. Patel, Tatiana Plavina, David H. Wilson, Lei Chang, Kim M. Kaiser, Jacob Nattermann, Susanne V. Schmidt, Eicke Latz, Kevin Hrusovsky, Dawn Mattoon, Andrew J. Ball
Published 2021-03-01