Therapeutic genome editing: prospects and challenges

by Cox, David Benjamin Turitz, Platt, Randall Jeffrey, Zhang, Feng
Published 2016

Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

by Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig H., Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew L.
Published 2011

Injectable Self-Healing Glucose-Responsive Hydrogels with pH-Regulated Mechanical Properties

by Yesilyurt, Volkan, Webber, Matthew, Appel, Eric, Godwin, Colin, Langer, Robert S, Anderson, Daniel Griffith
Published 2017

Label-free volumetric optical imaging of intact murine brains

by Ren, Jianbiao, Choi, Heejin, Chung, Kwanghun, Bouma, Brett E
Published 2017

Supramolecular PEGylation of biopharmaceuticals

by Vinciguerra, Brittany, Thapa, Lavanya S., Jhunjhunwala, Siddharth, Isaacs, Lyle, Webber, Matthew, Appel, Eric, Cortinas, Abel Bryan, Langer, Robert S, Anderson, Daniel Griffith
Published 2017

Simultaneous or Sequential Orthogonal Gradient Formation in a 3D Cell Culture Microfluidic Platform

by Uzel, Sebastien GM, Amadi, Ovid C, Pearl, Taylor M., Lee, Richard T, So, Peter T. C., Kamm, Roger Dale
Published 2017

Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference

by Singh, Neetu, Agrawal, Amit, Leung, Anthony, Sharp, Phillip A., Bhatia, Sangeeta N.
Published 2011

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope

by Tharakaraman, Kannan, Rowley, Kirk J, Costa, Vivian V, Chan, Kuan Rong, Wong, Yee Hwa, Ong, Li Ching, Tan, Hwee Cheng, Koch, Tyree, Viswanathan, Karthik, Liew, Chong Wai, Tissire, Hamid, Ramakrishnan, Boopathy, Myette, James R, Babcock, Gregory J, Alonso, Sylvie, Lescar, Julien, Shriver, Zachary, Ooi, Eng Eong, Robinson, Luke Nathaniel, Kirloskar, Rama Sanjay, Sasisekharan, Viswanathan, Chen, Jianzhu, Sasisekharan, Ram, Cain, David
Published 2016

Structure-based prediction reveals capping motifs that inhibit beta-helix aggregation

by Bryan, Allen W., Starner-Kreinbrink, Jennifer L., Hosur, Raghavendra, Clark, Patricia L., Berger, Bonnie
Published 2011

A Synaptic Strategy for Consolidation of Convergent Visuotopic Maps

by Phillips, Marnie A, Colonnese, Matthew T, Goldberg, Julie, Lewis, Laura D., Brown, Emery N., Constantine-Paton, Martha
Published 2015

Cardiac Ablation Catheter Guidance by Means of a Single Equivalent Moving Dipole Inverse Algorithm

by Lee, Kichang, Lv, Wener, Ter-Ovanesyan, Evgeny, Barley, Maya E., Voysey, Graham E., Galea, Anna M., Hirschman, Gordon B., Leroy, Kristen, Marini, Robert P., Barrett, Conor, Armoundas, Antonis A., Cohen, Richard J.
Published 2016

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates

by Acker, Leah Christine, Pino, Erica N., Boyden, Edward, Desimone, Robert
Published 2017

Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice

by Yin, Hao, Zeigerer, Anja, Nonaka, Hidenori, Zerial, Marino, Koteliansky, Victor, Anderson, Daniel Griffith, Ruda, Vera, Bogorad, Roman
Published 2016

MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13

by Sankaran, Vijay G., Menne, Tobias F., Scepanovic, Danilo, Vergilio, Jo-Anne, Ji, Peng, Kim, Jinkuk, Thiru, Prathapan, Orkin, Stuart H., Lander, Eric Steven, Lodish, Harvey F
Published 2011

Recurrent and functional regulatory mutations in breast cancer

by Parasuraman, Prasanna, Tiao, Grace, Kim, Jaegil, Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Engreitz, Jesse Michael, Lander, Eric Steven, Rheinbay, Esther, Lawrence, Michael, Cortes, Maria, Gabriel, Stacey, Golub, Todd, Getz, Gad Asher, Meyerson, Matthew L.
Published 2018

Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology

by Rothdiener, M., Bast, S., Uynuk-Ool, T., Zouhair, S., Ochs, B.G, De Zwart, P., Stoeckle, U., Aicher, W.K, Hart, M.L, Shiozawa, T., Schenke-Layland, K., Venkatesan, J.K, Cucchiarini, M., Madry, H., Kurz, B., Felka, Tino, Grodzinsky, Alan J, Rolauffs, Bernd G
Published 2018

Thalamic reticular nucleus induces fast and local modulation of arousal state

by Voigts, Jakob, Lewis, Laura D., Flores Plaza, Francisco Javier, Schmitt, Lukas I., Wilson, Matthew A., Halassa, Michael M., Brown, Emery N.
Published 2015

Measuring Growth and Gene Expression Dynamics of Tumor-Targeted S. Typhimurium Bacteria

by Danino, Tal, Prindle, Arthur, Hasty, Jeff, Bhatia, Sangeeta N., Bhatia, Sangeeta N
Published 2014

Survey of variation in human transcription factors reveals prevalent DNA binding changes

by Vedenko, A., Kurland, J. V., Rogers, J. M., Gisselbrecht, S. S., Woodard, J., Mariani, L., Kock, K. H., Inukai, S., Siggers, T., Shokri, L., Gordan, R., Sahni, N., Cotsapas, C., Hao, T., Yi, S., Vidal, M., Hill, D. E., Barrera, Luis Alberto, Rossin, Elizabeth, Kellis, Manolis, Daly, Mark J., Bulyk, Martha L.
Published 2017

Searching for the nik Operon: How a Ligand-Responsive Transcription Factor Hunts for Its DNA Binding Site

by Phillips, Christine M., Stultz, Collin M, Drennan, Catherine L
Published 2012