BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity

by Rikke D. Rasmussen, Madhavsai K. Gajjar, Lucie Tuckova, Kamilla E. Jensen, Apolinar Maya-Mendoza, Camilla B. Holst, Kjeld Møllgaard, Jane S. Rasmussen, Jannick Brennum, Jiri Bartek, Martin Syrucek, Eva Sedlakova, Klaus K. Andersen, Marie H. Frederiksen, Jiri Bartek, Petra Hamerlik
Published 2016-11-01

A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors.

by Alba Corman, Dimitris C Kanellis, Patrycja Michalska, Maria Häggblad, Vanesa Lafarga, Jiri Bartek, Jordi Carreras-Puigvert, Oscar Fernandez-Capetillo
Published 2021-05-01

Microthermal-induced subcellular-targeted protein damage in cells on plasmonic nanosilver-modified surfaces evokes a two-phase HSP-p97/VCP response

by Martin Mistrik, Zdenek Skrott, Petr Muller, Ales Panacek, Lucie Hochvaldova, Katarina Chroma, Tereza Buchtova, Veronika Vandova, Libor Kvitek, Jiri Bartek
Published 2021-01-01

Impact of meningioma surgery on use of antiepileptic, antidepressant, and sedative drugs: A Swedish nationwide matched cohort study

by Erik Thurin, Isabelle Rydén, Thomas Skoglund, Anja Smits, Sasha Gulati, Göran Hesselager, Jiri Bartek Jr, Roger Henriksson, Øyvind Salvesen, Asgeir S. Jakola
Published 2021-05-01

Long-Term Follow-Up and Predictors of Functional Outcome after Surgery for Spinal Meningiomas: A Population-Based Cohort Study

by Jenny Pettersson-Segerlind, Alexander Fletcher-Sandersjöö, Charles Tatter, Gustav Burström, Oscar Persson, Petter Förander, Tiit Mathiesen, Jiri Bartek, Erik Edström, Adrian Elmi-Terander
Published 2021-06-01

MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancer.

by Hanna Peurala, Dario Greco, Tuomas Heikkinen, Sippy Kaur, Jirina Bartkova, Maral Jamshidi, Kristiina Aittomäki, Päivi Heikkilä, Jiri Bartek, Carl Blomqvist, Ralf Bützow, Heli Nevanlinna
Published 2011-01-01

Aberrantly elevated suprabasin in the bone marrow as a candidate biomarker of advanced disease state in myelodysplastic syndromes

by Miroslav Pribyl, Sona Hubackova, Alena Moudra, Marketa Vancurova, Helena Polackova, Tomas Stopka, Anna Jonasova, Radka Bokorova, Ota Fuchs, Jan Stritesky, Barbora Salovska, Jiri Bartek, Zdenek Hodny
Published 2020-10-01

A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection

by Ana López-Saavedra, Daniel Gómez-Cabello, María Salud Domínguez-Sánchez, Fernando Mejías-Navarro, María Jesús Fernández-Ávila, Christoffel Dinant, María Isabel Martínez-Macías, Jiri Bartek, Pablo Huertas
Published 2016-08-01

Correction: Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity

by Robert Strauss, Zong-Yi Li, Ying Liu, Ines Beyer, Jonas Persson, Pavel Sova, Thomas Möller, Sari Pesonen, Akseli Hemminki, Petra Hamerlik, Charles Drescher, Nicole Urban, Jiri Bartek, André Lieber
Published 2011-01-01

FBH1 Catalyzes Regression of Stalled Replication Forks

by Kasper Fugger, Martin Mistrik, Kai J. Neelsen, Qi Yao, Ralph Zellweger, Arne Nedergaard Kousholt, Peter Haahr, Wai Kit Chu, Jiri Bartek, Massimo Lopes, Ian D. Hickson, Claus Storgaard Sørensen
Published 2015-03-01

Correction: Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity.

by Robert Strauss, Zong-Yi Li, Ying Liu, Ines Beyer, Jonas Persson, Pavel Sova, Thomas Möller, Sari Pesonen, Akseli Hemminki, Petra Hamerlik, Charles Drescher, Nicole Urban, Jiri Bartek, André Lieber
Published 2011-01-01

Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity.

by Robert Strauss, Zong-Yi Li, Ying Liu, Ines Beyer, Jonas Persson, Pavel Sova, Thomas Möller, Sari Pesonen, Akseli Hemminki, Petra Hamerlik, Charles Drescher, Nicole Urban, Jiri Bartek, André Lieber
Published 2011-01-01

Interferon‐regulated suprabasin is essential for stress‐induced stem‐like cell conversion and therapy resistance of human malignancies

by Sona Hubackova, Miroslav Pribyl, Lenka Kyjacova, Alena Moudra, Rastislav Dzijak, Barbora Salovska, Hynek Strnad, Vojtech Tambor, Terezie Imrichova, Jiri Svec, Pavel Vodicka, Radka Vaclavikova, Lukas Rob, Jiri Bartek, Zdenek Hodny
Published 2019-07-01

Mesothelin-specific Immune Responses Predict Survival of Patients With Brain Metastasis

by Liu Zhenjiang, Martin Rao, Xiaohua Luo, Elisabeth Sandberg, Jiri Bartek, Jr, Esther Schoutrop, Anna von Landenberg, Qingda Meng, Davide Valentini, Thomas Poiret, Georges Sinclair, Inti-Harvey Peredo, Ernest Dodoo, Markus Maeurer
Published 2017-09-01

Tumor-infiltrating lymphocytes (TILs) from patients with glioma

by Zhenjiang Liu, Qingda Meng, Jiri Bartek, Thomas Poiret, Oscar Persson, Lalit Rane, Elena Rangelova, Christopher Illies, Inti Harvey Peredo, Xiaohua Luo, Martin Vijayakumar Rao, Rebecca Axelsson Robertson, Ernest Dodoo, Markus Maeurer
Published 2017-02-01

Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition

by Patrik Oleksak, Miroslav Psotka, Marketa Vancurova, Olena Sapega, Jana Bieblova, Milan Reinis, David Rysanek, Romana Mikyskova, Katarina Chalupova, David Malinak, Jana Svobodova, Rudolf Andrys, Helena Rehulkova, Vojtech Skopek, Pham Ngoc Lam, Jiri Bartek, Zdenek Hodny, Kamil Musilek
Published 2021-01-01

Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease.

by Jane J Sohn, Aaron J Schetter, Harris G Yfantis, Lisa A Ridnour, Izumi Horikawa, Mohammed A Khan, Ana I Robles, S Perwez Hussain, Akiteru Goto, Elise D Bowman, Lorne J Hofseth, Jirina Bartkova, Jiri Bartek, Gerald N Wogan, David A Wink, Curtis C Harris
Published 2012-01-01

SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

by Elisabeth Anne Adanma Obara, Diana Aguilar-Morante, Rikke Darling Rasmussen, Alex Frias, Kristoffer Vitting-Serup, Yi Chieh Lim, Kirstine Juul Elbæk, Henriette Pedersen, Lina Vardouli, Kamilla Ellermann Jensen, Jane Skjoth-Rasmussen, Jannick Brennum, Lucie Tuckova, Robert Strauss, Christoffel Dinant, Jiri Bartek, Petra Hamerlik
Published 2020-09-01

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

by Panagiotis Galanos, George Pappas, Alexander Polyzos, Athanassios Kotsinas, Ioanna Svolaki, Nickolaos N. Giakoumakis, Christina Glytsou, Ioannis S. Pateras, Umakanta Swain, Vassilis L. Souliotis, Alexandros G. Georgakilas, Nicholas Geacintov, Luca Scorrano, Claudia Lukas, Jiri Lukas, Zvi Livneh, Zoi Lygerou, Dipanjan Chowdhury, Claus Storgaard Sørensen, Jiri Bartek, Vassilis G. Gorgoulis
Published 2018-03-01

Correction to: A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence

by Eirini-Stavroula Komseli, Ioannis S. Pateras, Thorbjørn Krejsgaard, Konrad Stawiski, Sophia V. Rizou, Alexander Polyzos, Fani-Marlen Roumelioti, Maria Chiourea, Ioanna Mourkioti, Eleni Paparouna, Christos P. Zampetidis, Sentiljana Gumeni, Ioannis P. Trougakos, Dafni-Eleftheria Pefani, Eric O’Neill, Sarantis Gagos, Aristides G. Eliopoulos, Wojciech Fendler, Dipanjan Chowdhury, Jiri Bartek, Vassilis G. Gorgoulis
Published 2021-05-01