Evaluation of Potency of Known Oximes (Pralidoxime, Trimedoxime, HI-6, Methoxime, Obidoxime) to in vitro Reactivate Acetylcholinesterase Inhibited by Pesticides (Chlorpyrifos and M...

by Kamil Musílek, Kamil Kuča, Daniel Jun
Published 2007-01-01

In Vitro Ability of Currently Available Oximes to Reactivate Organophosphate Pesticide-Inhibited Human Acetylcholinesterase and Butyrylcholinesterase

by Kamil Musilek, Kamil Kuca, Daniel Jun, Lucie Musilova
Published 2011-03-01

Novel Group of AChE Reactivators—Synthesis, In Vitro Reactivation and Molecular Docking Study

by David Malinak, Eugenie Nepovimova, Daniel Jun, Kamil Musilek, Kamil Kuca
Published 2018-09-01

A Comparison of the Potency of Newly Developed Oximes (K347, K628) and Currently Available Oximes (Obidoxime, HI-6) to Counteract Acute Neurotoxic Effects of Tabun in Rats

by Jiří Kassa, Jana Žďárová Karasová, Sandra Tesařová, Kamil Musílek, Kamil Kuča
Published 2010-01-01

A Comparison of the Neuroprotective Efficacy of Newly Developed Oximes (K156, K203) and Currently Available Oximes (Obidoxime, HI-6) in Cyclosarin-poisoned Rats

by Jiří Kassa, Jana Žďárová Karasová, Sandra Tesařová, Kamil Kuča, Kamil Musílek
Published 2008-01-01

Two Step Synthesis of a Non-symmetric Acetylcholinesterase Reactivator

by Vit Koleckar, Jan Marek, Daniel Jun, Vlastimil Dohnal, Kamil Kuca, Kamil Musilek
Published 2007-08-01

Effect of Seven Newly Synthesized and Currently Available Oxime Cholinesterase Reactivators on Cyclosarin-Intoxicated Rats

by Kamil Kuca, Ladislav Novotny, Kamil Musilek, Miroslav Pohanka, Jiri Kassa, Jana Zdarova Karasova
Published 2009-07-01

Effect of Several New and Currently Available Oxime Cholinesterase Reactivators on Tabun-intoxicated Rats

by Jiri Kassa, Jana Zdarova Karasova, Young-Sik Jung, Kamil Musilek, Miroslav Pohanka, Kamil Kuca
Published 2008-11-01

Preparation of Benzalkonium Salts Differing in the Length of a Side Alkyl Chain

by Daniel Jun, Martina Hrabinova, Petra Hanusova, Kamil Musilek, Petr Stodulka, Jan Marek, Kamil Kuca
Published 2007-10-01

Targeted Synthesis of 1-(4-Hydroxyiminomethylpyridinium)-3-pyridiniumpropane Dibromide – A New Nerve Agent Reactivator

by Jan Marek, Martina Hrabinova, Petr Stodulka, Daniel Jun, Martin Paar, Kamil Musilek, Kamil Kuca
Published 2007-08-01

Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase

by Jakub Jończyk, Jędrzej Kukułowicz, Kamil Łątka, Barbara Malawska, Young-Sik Jung, Kamil Musilek, Marek Bajda
Published 2021-01-01

1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy

by Barbara Kaproń, Robert Czarnomysy, Mariusz Wysokiński, Rudolf Andrys, Kamil Musilek, Andrea Angeli, Claudiu T. Supuran, Tomasz Plech
Published 2020-01-01

Preparation of the Pyridinium Salts Differing in the Length of the N-Alkyl Substituent

by Kamil Musilek, Jan Korabecny, Miroslav Pohanka, Ondrej Soukup, Jiri Cabal, Petr Stodulka, Jan Marek, Kamil Kuca
Published 2010-03-01

Preparation of Quinolinium Salts Differing in the Length of the Alkyl Side Chain

by Kamil Kuca, Kallol K. Ghosh, Kamil Musilek, Jiri Cabal, Petr Stodulka, Ondrej Soukup, Vladimir Buchta, Jan Marek
Published 2012-05-01

Molecular Modeling Studies on the Interactions of Aflatoxin B1 and Its Metabolites with Human Acetylcholinesterase. Part II: Interactions with the Catalytic Anionic Site (CAS)

by Joyce S. F. D. de Almeida, Rafael Dolezal, Ondrej Krejcar, Kamil Kuca, Kamil Musilek, Daniel Jun, Tanos C. C. França
Published 2018-09-01

Anticipated Social and Healthcare Economic Burden of People with Alzheimer’s Disease in Two Selected Regions of the Czech Republic

by Petra Maresova, Lenka Komarkova, Jitka Kuhnova, Richard Cimler, Peter Pazitny, Daniela Kandilaki, Kamil Musilek, Zuzana Truhlarova, Filip Zemek, Kamil Kuca
Published 2020-10-01

7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer’s Disease Treatment — Synthesis, Biological Evaluation and Molecular Modeling Studies

by Kamil Kuca, Katarina Siposova, Lucie Drtinova, Zuzana Gazova, Ondrej Soukup, Kamil Musilek, Anna Horova, Katarina Spilovska, Jan Korabecny, Jan Kral
Published 2013-02-01

QSAR Study of N-Myristoyltransferase Inhibitors of Antimalarial Agents

by Letícia Santos-Garcia, Marco Antônio de Mecenas Filho, Kamil Musilek, Kamil Kuca, Teodorico Castro Ramalho, Elaine Fontes Ferreira da Cunha
Published 2018-09-01

Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon

by Daniel Jun, Jana Zdarova Karasova, Miroslav Pohanka, Martina Hrabinova, Kamil Musilek, Martin Paar, Vladimir Cirkva, Jiri Palecek, Kamil Kuca, Lucie Musilova
Published 2009-12-01

1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders

by Ondrej Benek, Lukas Hroch, Laura Aitken, Frank Gunn-Moore, Lucie Vinklarova, Kamil Kuca, Daniel I. Perez, Concepcion Perez, Ana Martinez, Zdenek Fisar, Kamil Musilek
Published 2018-01-01