The Evaluation of the Potency of Newly Developed Oximes (K727, K733) and Trimedoxime to Counteract Acute Neurotoxic Effects of Tabun in Rats

by Jiří Kassa, Jana Hatlapatková, Jana Žďárová Karasová
Published 2016-03-01

A Comparison of the Potency of Newly Developed Oximes (K347, K628) and Currently Available Oximes (Obidoxime, HI-6) to Counteract Acute Neurotoxic Effects of Tabun in Rats

by Jiří Kassa, Jana Žďárová Karasová, Sandra Tesařová, Kamil Musílek, Kamil Kuča
Published 2010-01-01

A Comparison of the Neuroprotective Efficacy of Newly Developed Oximes (K156, K203) and Currently Available Oximes (Obidoxime, HI-6) in Cyclosarin-poisoned Rats

by Jiří Kassa, Jana Žďárová Karasová, Sandra Tesařová, Kamil Kuča, Kamil Musílek
Published 2008-01-01

The Ability of Oxime Mixtures to Increase the Reactivating and Therapeutic Efficacy of Antidotal Treatment of Cyclosarin Poisoning in Rats and Mice

by Jiří Kassa, Jana Zdarová Karasová, Růžena Pavlíková, Filip Caisberger, Jiří Bajgar
Published 2012-01-01

Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?

by Jana Zdarova Karasova, Martin Mzik, Tomas Kucera, Zbynek Vecera, Jiri Kassa, Vit Sestak
Published 2020-10-01

Evaluation of Cholinesterase Activities During in Vivo Intoxication Using an Electrochemical Sensor Strip – Correlation With Intoxication Symptoms

by Jana Zdarova-Karasova, Martina Hrabinova, Kamil Kuca, Ladislav Novotný, Jan Misík, Miroslav Pohanka
Published 2009-05-01

Effect of Seven Newly Synthesized and Currently Available Oxime Cholinesterase Reactivators on Cyclosarin-Intoxicated Rats

by Kamil Kuca, Ladislav Novotny, Kamil Musilek, Miroslav Pohanka, Jiri Kassa, Jana Zdarova Karasova
Published 2009-07-01

Effect of Several New and Currently Available Oxime Cholinesterase Reactivators on Tabun-intoxicated Rats

by Jiri Kassa, Jana Zdarova Karasova, Young-Sik Jung, Kamil Musilek, Miroslav Pohanka, Kamil Kuca
Published 2008-11-01

The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats—A Comparison with Trimedoxime and the...

by Jiri Kassa, Jan Misik, Jana Hatlapatkova, Jana Zdarova Karasova, Vendula Sepsova, Filip Caisberger, Jaroslav Pejchal
Published 2017-07-01

Oximes: Inhibitors of Human Recombinant Acetylcholinesterase. A Structure-Activity Relationship (SAR) Study

by Kamil Kuca, Brian J. Bennion, Rafael Dolezal, Filip Zemek, Vendula Sepsova, Jana Zdarova Karasova, Jan Korabecny
Published 2013-08-01

The Concentration of Memantine in the Cerebrospinal Fluid of Alzheimer’s Disease Patients and Its Consequence to Oxidative Stress Biomarkers

by Martin Valis, David Herman, David Herman, Nela Vanova, Nela Vanova, Jiri Masopust, Jiri Masopust, Oldrich Vysata, Jakub Hort, Jakub Hort, Zbysek Pavelek, Blanka Klimova, Kamil Kuca, Jan Misik, Jan Misik, Jana Zdarova Karasova, Jana Zdarova Karasova
Published 2019-08-01

Dextran Sodium Sulphate-Induced Gastrointestinal Injury Further Aggravates the Impact of Galantamine on the Gastric Myoelectric Activity in Experimental Pigs

by Jan Bures, Ilja Tacheci, Jaroslav Kvetina, Vera Radochova, Darina Kohoutova, Martin Valis, Stanislav Rejchrt, Veronika Knoblochova, Jana Zdarova Karasova
Published 2021-06-01

Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon

by Daniel Jun, Jana Zdarova Karasova, Miroslav Pohanka, Martina Hrabinova, Kamil Musilek, Martin Paar, Vladimir Cirkva, Jiri Palecek, Kamil Kuca, Lucie Musilova
Published 2009-12-01

The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs.

by Jan Bures, Jaroslav Kvetina, Vera Radochova, Ilja Tacheci, Eva Peterova, David Herman, Rafael Dolezal, Marcela Kopacova, Stanislav Rejchrt, Tomas Douda, Vit Sestak, Ladislav Douda, Jana Zdarova Karasova
Published 2020-01-01

The Impact of Dextran Sodium Sulfate-Induced Gastrointestinal Injury on the Pharmacokinetic Parameters of Donepezil and Its Active Metabolite 6-<i>O</i>-desmethyldonepezil, and Gas...

by Jan Bures, Ilja Tacheci, Jaroslav Kvetina, Vera Radochova, Lukas Prchal, Darina Kohoutova, Martin Valis, Martin Novak, Rafael Dolezal, Marcela Kopacova, Stanislav Rejchrt, Vit Sestak, Veronika Knoblochova, Eva Peterova, Jana Zdarova Karasova
Published 2021-04-01

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase

by Kamil Kuca, Kamil Musilek, Daniel Jun, Jana Zdarova-Karasova, Eugenie Nepovimova, Ondrej Soukup, Martina Hrabinova, John Mikler, Tanos C. C. Franca, Elaine F. F. Da Cunha, Alexandre A. De Castro, Martin Valis, Teodorico C. Ramalho
Published 2018-02-01