Tyro3-mediated phosphorylation of ACTN4 at tyrosines is FAK-dependent and decreases susceptibility to cleavage by m-Calpain

by Shao, Hanshuang, Wang, Anna, Wells, Alan, Lauffenburger, Douglas A
Published 2019

Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer

by Miller, Miles A., Sullivan, Ryan J., Lauffenburger, Douglas A
Published 2018

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

by Yu, Wen-Han, Das, Jishnu, Lauffenburger, Douglas A, Alter, Galit
Published 2020

Acidic Extracellular pH Promotes Activation of Integrin [alpha]v[beta]3

by Paradise, Ranjani K., Lauffenburger, Douglas A., Van Vliet, Krystyn J.
Published 2011

Integrated network analyses for functional genomic studies in cancer

by Fraenkel, Ernest, Wilson, Jennifer Lynn, Hemann, Michael, Lauffenburger, Douglas A
Published 2014

A Dynamical Systems Model for Combinatorial Cancer Therapy Enhances Oncolytic Adenovirus Efficacy by MEK-Inhibition

by Bagheri, Nada, Shiina, Marisa, Lauffenburger, Douglas A., Korn, W. Michael
Published 2011

Synergistic Communication between CD4+ T Cells and Monocytes Impacts the Cytokine Environment

by Schrier, Sarah B., Hill, Abby, Plana, Deborah, Lauffenburger, Douglas A
Published 2017

Controlling multipotent stromal cell migration by integrating "course-graining" materials and "fine-tuning" small molecules via decision tree signal-response modeling

by Wu, Shan, Wells, Alan, Griffith, Linda G., Lauffenburger, Douglas A.
Published 2015

Addressing Genetic Tumor Heterogeneity through Computationally Predictive Combination Therapy

by Zhao, Boyang, Pritchard, Justin R., Hemann, Michael, Lauffenburger, Douglas A
Published 2014

Integration of multiple signaling pathway activities resolves K-RAS/N-RAS mutation paradox in colon epithelial cell response to inflammatory cytokine stimulation

by Kreeger, Pamela K., Wang, Yufang, Haigis, Kevin M., Lauffenburger, Douglas A
Published 2012

Computational translation of genomic responses from experimental model systems to humans

by Haigis, Kevin M., Brubaker, Douglas, Proctor, Elizabeth A, Lauffenburger, Douglas A
Published 2019

Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

by Aldridge, Bree B., Gaudet, Suzanne, Lauffenburger, Douglas A., Sorger, Peter K.
Published 2013

Predicting cancer drug mechanisms of action using molecular network signatures

by Pritchard, Justin R., Bruno, Peter Michael, Hemann, Michael, Lauffenburger, Douglas A
Published 2014

The Receptor AXL Diversifies EGFR Signaling and Limits the Response to EGFR-Targeted Inhibitors in Triple-Negative Breast Cancer Cells

by Meyer, Aaron Samuel, Miller, Miles Aaron, Gertler, Frank, Lauffenburger, Douglas A
Published 2014

Targeting tumor cell motility as a strategy against invasion and metastasis

by Wells, Alan, Grahovac, Jelena, Wheeler, Sarah, Ma, Bo, Lauffenburger, Douglas A.
Published 2015

Differential selective pressure alters rate of drug resistance acquisition in heterogeneous tumor populations

by Sun, Daphne S., Dalin, Simona, Hemann, Michael, Lauffenburger, Douglas A, Zhao, Boyang
Published 2017

Querying quantitative logic models (Q2LM) to study intracellular signaling networks and cell-cytokine interactions

by Morris, Melody Kay, Sasisekharan, Ram, Lauffenburger, Douglas A., Shriver, Zachary H.
Published 2013

PKCδ Localization at the Membrane Increases Matrix Traction Force Dependent on PLCγ1/EGFR Signaling

by Jamison, Joshua, Wang, James C.-H, Wells, Alan, Lauffenburger, Douglas A.
Published 2014

Cellular defense processes regulated by pathogen-elicited receptor signaling

by Wu, Rongcong, Goldsipe, Arthur C., Schauer, David B., Lauffenburger, Douglas A.
Published 2014

Microfluidic Concentration-Enhanced Cellular Kinase Activity Assay

by Lee, Jeong Hoon, Cosgrove, Benjamin D., Lauffenburger, Douglas A., Han, Jongyoon
Published 2010