Inherited Disease Genetics Improves the Identification of Cancer-Associated Genes

by Pritchard, Justin R., Zhao, Boyang
Published 2016

Understanding resistance to combination chemotherapy

by Pritchard, Justin R., Hemann, Michael, Lauffenburger, Douglas A
Published 2014

Addressing Genetic Tumor Heterogeneity through Computationally Predictive Combination Therapy

by Zhao, Boyang, Pritchard, Justin R., Hemann, Michael, Lauffenburger, Douglas A
Published 2014

Predicting cancer drug mechanisms of action using molecular network signatures

by Pritchard, Justin R., Bruno, Peter Michael, Hemann, Michael, Lauffenburger, Douglas A
Published 2014

A mammalian functional-genetic approach to characterizing cancer therapeutics

by Williams, Richard T., Jiang, Hai, Hemann, Michael, Pritchard, Justin R., Lauffenburger, Douglas A
Published 2011

Three-kinase inhibitor combination recreates multipathway effects of a geldanamycin analogue on hepatocellular carcinoma cell death

by Wands, Jack R., Cosgrove, Benjamin D., Hemann, Michael, Pritchard, Justin R., Griffith, Linda G, Lauffenburger, Douglas A
Published 2011

Defining principles of combination drug mechanisms of action

by Bruno, Peter Michael, Gilbert, Luke Andrew, Capron, Kelsey L., Hemann, Michael, Pritchard, Justin R., Lauffenburger, Douglas A
Published 2013

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

by Zhao, Boyang, Srinivas, Raja Ram, Creixell Morera, Pau, Tidor, Bruce, Lauffenburger, Douglas A, Hemann, Michael, Pritchard, Justin R.
Published 2017

BCL-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response

by Gilbert, Luke Andrew, Meacham, Corbin Elizabeth, Jiang, Hai, Hemann, Michael, Pritchard, Justin R., Shingleton, Jennifer R., Lauffenburger, Douglas A
Published 2013

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

by Murai, Junko, Pommier, Yves, Hemann, Michael T, Bruno, Peter Michael, Liu, Yunpeng, Park, Ga Young, Koch, Catherine E., Lippard, Stephen J., Hemann, Michael, Eisen, Timothy Jonas, Pritchard, Justin R.
Published 2018

A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

by Meacham, Corbin Elizabeth, Lawton, Lee N., Pritchard, Justin R., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Soto Feliciano, Yadira Marie, Hemann, Michael, Joughin, Brian Alan
Published 2015