O8 Integration site detection in 10 chronically infected patients

by Basiel Cole, Maja Kiselinova, Sherry McLaughlin, Sheila Styrchak, Ward De Spiegelaere, MariaJose Buzon, Mathias Lichterfeld, Lisa Frenkel, Linos Vandekerckhove
Published 2017-09-01

Early treated HIV-1 positive individuals demonstrate similar restriction factor expression profile as long-term non-progressorsResearch in context

by Clarissa Van Hecke, Wim Trypsteen, Eva Malatinkova, Ward De Spiegelaere, Karen Vervisch, Sofie Rutsaert, Sabine Kinloch-de Loes, Magdalena Sips, Linos Vandekerckhove
Published 2019-03-01

Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phas...

by Sofie Rutsaert, Jean-Marc Steens, Paul Gineste, Basiel Cole, Sam Kint, P. Noel Barrett, Jamal Tazi, Didier Scherrer, Hartmut J. Ehrlich, Linos Vandekerckhove
Published 2019-01-01

Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged In Vitro Peptide Stimulation

by Philipp Adams, Philipp Adams, Philipp Adams, Gilles Iserentant, Jean-Yves Servais, Linos Vandekerckhove, Guido Vanham, Guido Vanham, Carole Seguin-Devaux, the PhenoCure Study Group
Published 2021-02-01

Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.

by Anneleen Hombrouck, Jan De Rijck, Jelle Hendrix, Linos Vandekerckhove, Arnout Voet, Marc De Maeyer, Myriam Witvrouw, Yves Engelborghs, Frauke Christ, Rik Gijsbers, Zeger Debyser
Published 2007-03-01

Reference gene validation for RT-qPCR, a note on different available software packages.

by Ward De Spiegelaere, Jutta Dern-Wieloch, Roswitha Weigel, Valérie Schumacher, Hubert Schorle, Daniel Nettersheim, Martin Bergmann, Ralph Brehm, Sabine Kliesch, Linos Vandekerckhove, Cornelia Fink
Published 2015-01-01

Gold Nanoparticle-Mediated Photoporation Enables Delivery of Macromolecules over a Wide Range of Molecular Weights in Human CD4+ T Cells

by Laurens Raes, Clarissa Van Hecke, Julie Michiels, Stephan Stremersch, Juan C. Fraire, Toon Brans, Ranhua Xiong, Stefaan De Smedt, Linos Vandekerckhove, Koen Raemdonck, Kevin Braeckmans
Published 2019-08-01

In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia

by Basiel Cole, Laurens Lambrechts, Pierre Gantner, Ytse Noppe, Noah Bonine, Wojciech Witkowski, Lennie Chen, Sarah Palmer, James I. Mullins, Nicolas Chomont, Marion Pardons, Linos Vandekerckhove
Published 2021-06-01

CD32+CD4+ memory T cells are enriched for total HIV-1 DNA in tissues from humanized mice

by Philipp Adams, Virginie Fievez, Rafaëla Schober, Mathieu Amand, Gilles Iserentant, Sofie Rutsaert, Géraldine Dessilly, Guido Vanham, Fanny Hedin, Antonio Cosma, Michel Moutschen, Linos Vandekerckhove, Carole Seguin-Devaux
Published 2021-01-01

Long non-coding RNAs and latent HIV - A search for novel targets for latency reversal.

by Wim Trypsteen, Cory H White, Amey Mukim, Celsa A Spina, Ward De Spiegelaere, Steve Lefever, Vicente Planelles, Alberto Bosque, Christopher H Woelk, Linos Vandekerckhove, Nadejda Beliakova-Bethell
Published 2019-01-01

Impact of a decade of successful antiretroviral therapy initiated at HIV-1 seroconversion on blood and rectal reservoirs

by Eva Malatinkova, Ward De Spiegelaere, Pawel Bonczkowski, Maja Kiselinova, Karen Vervisch, Wim Trypsteen, Margaret Johnson, Chris Verhofstede, Danny de Looze, Charles Murray, Sabine Kinloch-de Loes, Linos Vandekerckhove
Published 2015-10-01

Impact of the HIV-1 genetic background and HIV-1 population size on the evolution of raltegravir resistance

by Axel Fun, Thomas Leitner, Linos Vandekerckhove, Martin Däumer, Alexander Thielen, Bernd Buchholz, Andy I. M. Hoepelman, Elizabeth H. Gisolf, Pauline J. Schipper, Annemarie M. J. Wensing, Monique Nijhuis
Published 2018-01-01

Highlights from the 24th Conference on Retroviruses and Opportunistic Infections

by Trevor A. Crowell, Hermione Lyall, Eva Malatinkova, Sanjay Bhagani, Denise Hsu, Donn J. Colby, Christina Polyak, Christina Psomas, Andrew Hill, Esther N. Gathogo, Wim Trypsteen, Linos Vandekerckhove, Sabie Kinloch
Published 2017-04-01

Erratum to: HIV integration sites in latently infected cell lines: evidence of ongoing replication

by Jori Symons, Abha Chopra, Eva Malatinkova, Ward De Spiegelaere, Shay Leary, Don Cooper, Chike O. Abana, Ajantha Rhodes, Simin D. Rezaei, Linos Vandekerckhove, Simon Mallal, Sharon R. Lewin, Paul U. Cameron
Published 2017-03-01

Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across clinical con...

by Glenn Vergauwen, Joeri Tulkens, Cláudio Pinheiro, Francisco Avila Cobos, Sándor Dedeyne, Marie‐Angélique De Scheerder, Linos Vandekerckhove, Francis Impens, Ilkka Miinalainen, Geert Braems, Kris Gevaert, Pieter Mestdagh, Jo Vandesompele, Hannelore Denys, Olivier De Wever, An Hendrix
Published 2021-08-01

Characterization of LEDGF/p75 genetic variants and association with HIV-1 disease progression.

by Peter Messiaen, Ward De Spiegelaere, Jose Alcami, Karen Vervisch, Petra Van Acker, Bruno Verhasselt, Pieter Meuwissen, Esther Calonge, Nuria Gonzalez, Felix Gutierrez-Rodero, Carmen Rodriguez-Martín, Erica Sermijn, Bruce Poppe, Dirk Vogelaers, Chris Verhofstede, Linos Vandekerckhove
Published 2012-01-01

During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ

by Alessandra Ruggiero, Ward De Spiegelaere, Alessandro Cozzi-Lepri, Maja Kiselinova, Georgios Pollakis, Apostolos Beloukas, Linos Vandekerckhove, Matthew Strain, Douglas Richman, Andrew Phillips, Anna Maria Geretti, Paola Vitiello, Nicola Mackie, Jonathan Ainsworth, Anele Waters, Frank Post, Simon Edwards, Julie Fox
Published 2015-09-01

Comparison of methods for in-house screening of HLA-B*57:01 to prevent abacavir hypersensitivity in HIV-1 care.

by Ward De Spiegelaere, Jan Philippé, Karen Vervisch, Chris Verhofstede, Eva Malatinkova, Maja Kiselinova, Wim Trypsteen, Pawel Bonczkowski, Dirk Vogelaers, Steven Callens, Jean Ruelle, Kabamba Kabeya, Stephane De Wit, Petra Van Acker, Vicky Van Sandt, Marie-Paule Emonds, Paul Coucke, Erica Sermijn, Linos Vandekerckhove
Published 2015-01-01

PCIP-seq: simultaneous sequencing of integrated viral genomes and their insertion sites with long reads

by Maria Artesi, Vincent Hahaut, Basiel Cole, Laurens Lambrechts, Fereshteh Ashrafi, Ambroise Marçais, Olivier Hermine, Philip Griebel, Natasa Arsic, Frank van der Meer, Arsène Burny, Dominique Bron, Elettra Bianchi, Philippe Delvenne, Vincent Bours, Carole Charlier, Michel Georges, Linos Vandekerckhove, Anne Van den Broeke, Keith Durkin
Published 2021-04-01

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells

by Wouter A. van der Heijden, Lisa Van de Wijer, Farid Keramati, Wim Trypsteen, Sofie Rutsaert, Rob ter Horst, Martin Jaeger, Hans J.P.M. Koenen, Hendrik G. Stunnenberg, Irma Joosten, Paul E. Verweij, Jan van Lunzen, Charles A. Dinarello, Leo A.B. Joosten, Linos Vandekerckhove, Mihai G. Netea, André J.A.M. van der Ven, Quirijn de Mast
Published 2021-04-01