HIV persistence in the setting of antiretroviral therapy: when, where and how does HIV hide?

by Deanna A. Kulpa, Nicolas Chomont
Published 2015-04-01

Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise

by Johann Plantin, Marta Massanella, Nicolas Chomont
Published 2018-01-01

Latency-Reversing Agents Induce Differential Responses in Distinct Memory CD4 T Cell Subsets in Individuals on Antiretroviral Therapy

by Marion Pardons, Rémi Fromentin, Amélie Pagliuzza, Jean-Pierre Routy, Nicolas Chomont
Published 2019-11-01

Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

by Pierre Gantner, Amélie Pagliuzza, Marion Pardons, Moti Ramgopal, Jean-Pierre Routy, Rémi Fromentin, Nicolas Chomont
Published 2020-08-01

Differences in HIV burden in the inflamed and non-inflamed colon from a person living with HIV and ulcerative colitis

by Xiaorong Peng, Stéphane Isnard, John Lin, Brandon Fombuena, Talat Bessissow, Nicolas Chomont, Jean-Pierre Routy
Published 2021-03-01

Fingolimod inhibits multiple stages of the HIV-1 life cycle.

by Rachel S Resop, Rémi Fromentin, Daniel Newman, Hawley Rigsby, Larisa Dubrovsky, Michael Bukrinsky, Nicolas Chomont, Alberto Bosque
Published 2020-08-01

Highlights from the Seventh International Workshop on HIV Persistence during Therapy, 8–11 December 2015, Miami, Florida, USA

by David M. Margolis, Karl Salzwedel, Nicolas Chomont, Christina Psomas, Jean-Pierre Routy, Guido Poli, Alain Lafeuillade
Published 2016-01-01

Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques.

by Emily S Ryan, Luca Micci, Rémi Fromentin, Sara Paganini, Colleen S McGary, Kirk Easley, Nicolas Chomont, Mirko Paiardini
Published 2016-02-01

Highlights from the 8th International Workshop on HIV Persistence during Therapy, 12–15 December 2017, Miami, FL, USA

by Christina K. Psomas, Alain Lafeuillade, David Margolis, Karl Salzwedel, Mario Stevenson, Nicolas Chomont, Guido Poli, Jean-Pierre Routy
Published 2018-04-01

Highlights of the 9th edition of the Conference on HIV Persistence During Therapy, 10–13 December 2019, Miami, USA

by ChristinaK Psomas, Karl Salzwedel, Mario Stevenson, Guido Poli, Jean-Pierre Routy, David Margolis, Nicolas Chomont, Alain Lafeuillade
Published 2020-04-01

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid

by Yuwei Zhang, Yuwei Zhang, Delphine Planas, Delphine Planas, Laurence Raymond Marchand, Marta Massanella, Marta Massanella, Huicheng Chen, Huicheng Chen, Vanessa Sue Wacleche, Vanessa Sue Wacleche, Annie Gosselin, Jean-Philippe Goulet, Mario Filion, Jean-Pierre Routy, Nicolas Chomont, Nicolas Chomont, Petronela Ancuta, Petronela Ancuta
Published 2020-05-01

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection.

by Marion Pardons, Amy E Baxter, Marta Massanella, Amélie Pagliuzza, Rémi Fromentin, Caroline Dufour, Louise Leyre, Jean-Pierre Routy, Daniel E Kaufmann, Nicolas Chomont
Published 2019-02-01

Loss of CD96 Expression as a Marker of HIV-Specific CD8+ T-Cell Differentiation and Dysfunction

by Rémi Bunet, Rémi Bunet, Manon Nayrac, Hardik Ramani, Hardik Ramani, Mohamed Sylla, Madeleine Durand, Madeleine Durand, Carl Chartrand-Lefebvre, Jean-Pierre Routy, Alan L. Landay, Jean-Francois Gauchat, Nicolas Chomont, Nicolas Chomont, Petronela Ancuta, Petronela Ancuta, Daniel E. Kaufmann, Daniel E. Kaufmann, Nicole Bernard, Cécile L. Tremblay, Cécile L. Tremblay, Mohamed El-Far
Published 2021-05-01

The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid.

by Vanessa Sue Wacleche, Nicolas Chomont, Annie Gosselin, Patricia Monteiro, Mathieu Goupil, Hassen Kared, Cécile Tremblay, Nicole Bernard, Mohamed-Rachid Boulassel, Jean-Pierre Routy, Petronela Ancuta
Published 2012-01-01

In-depth single-cell analysis of translation-competent HIV-1 reservoirs identifies cellular sources of plasma viremia

by Basiel Cole, Laurens Lambrechts, Pierre Gantner, Ytse Noppe, Noah Bonine, Wojciech Witkowski, Lennie Chen, Sarah Palmer, James I. Mullins, Nicolas Chomont, Marion Pardons, Linos Vandekerckhove
Published 2021-06-01

The evaluation of risk-benefit ratio for gut tissue sampling in HIV cure research

by Vikram Mehraj, Peter Ghali, Rayoun Ramendra, Cecilia Costiniuk, Bertrand Lebouché, Rosalie Ponte, Robert Reinhard, Jose Sousa, Nicolas Chomont, Eric A. Cohen, Petronela Ancuta, Jean-Pierre Routy
Published 2017-10-01

15 Pulmonary T cells and HIV reservoirs in adults under suppressive ART

by CeciliaT Costiniuk, Omar Farnos, Syim Salahuddin, Ron Olivenstein, Jean-Pierre Routy, Amélie Pagliuzza, Christina Castro, de, Jean Bourbeau, Bertrand Lebouché, Petronela Ancuta, Nicolas Chomont, Mohammad-Ali Jenabian
Published 2017-07-01

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy.

by Sulggi A Lee, Peter Bacchetti, Nicolas Chomont, Remi Fromentin, Sharon R Lewin, Una O'Doherty, Sarah Palmer, Douglas D Richman, Janet D Siliciano, Steven A Yukl, Steven G Deeks, Peter D Burbelo
Published 2016-01-01

Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy

by Eunok Lee, Eunok Lee, Peter Bacchetti, Jeffery Milush, Wei Shao, Eli Boritz, Daniel Douek, Remi Fromentin, Teri Liegler, Rebecca Hoh, Steve G. Deeks, Frederick M. Hecht, Nicolas Chomont, Sarah Palmer, Sarah Palmer
Published 2019-09-01

DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Con...

by Melanie Thompson, Sonya L Heath, Bentley Sweeton, Kathy Williams, Pamela Cunningham, Brandon F Keele, Sharon Sen, Brent E Palmer, Nicolas Chomont, Yongxian Xu, Rahul Basu, Michael S Hellerstein, Suefen Kwa, Harriet L Robinson
Published 2016-01-01