New Frontiers in Measuring and Characterizing the HIV Reservoir

by Shane D. Falcinelli, Shane D. Falcinelli, Cristina Ceriani, Cristina Ceriani, David M. Margolis, David M. Margolis, David M. Margolis, Nancie M. Archin, Nancie M. Archin
Published 2019-12-01

Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay

by Erin L. Stuelke, Katherine S. James, Jennifer L. Kirchherr, Brigitte Allard, Caroline Baker, Joann D. Kuruc, Joann D. Kuruc, Cindy L. Gay, Cindy L. Gay, David M. Margolis, David M. Margolis, David M. Margolis, David M. Margolis, Nancie M. Archin, Nancie M. Archin
Published 2020-08-01

HIV Latency Reversing Agents have diverse effects on Natural Killer Cell Function

by Carolina Garrido, Carolina Garrido, Adam M Spivak, Natalia Soriano-Sarabia, Natalia Soriano-Sarabia, Mary Ann Checkley, Edward Barker, Jonathan Karn, Vicente Planelles, David M Margolis, David M Margolis, David M Margolis
Published 2016-09-01

Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART® Molecules

by Marina Tuyishime, Amir Dashti, Katelyn Faircloth, Shalini Jha, Jeffrey L. Nordstrom, Barton F. Haynes, Barton F. Haynes, Barton F. Haynes, Guido Silvestri, Ann Chahroudi, Ann Chahroudi, Ann Chahroudi, David M. Margolis, David M. Margolis, David M. Margolis, David M. Margolis, Guido Ferrari, Guido Ferrari
Published 2021-08-01

Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency

by Todd Bradley, Guido Ferrari, Barton F. Haynes, David M. Margolis, Edward P. Browne
Published 2018-10-01

Highlights from the Seventh International Workshop on HIV Persistence during Therapy, 8–11 December 2015, Miami, Florida, USA

by David M. Margolis, Karl Salzwedel, Nicolas Chomont, Christina Psomas, Jean-Pierre Routy, Guido Poli, Alain Lafeuillade
Published 2016-01-01

Interrupting antiretroviral treatment in HIV cure research: scientific and ethical considerations

by Samual A. Garner, Stuart Rennie, Jintanat Ananworanich, Karine Dube, David M. Margolis, Jeremy Sugarman, Randall Tressler, Adam Gilbertson, Liza Dawson
Published 2017-04-01

Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection.

by Nancie M Archin, Manzoor Cheema, Daniel Parker, Ann Wiegand, Ronald J Bosch, John M Coffin, Joseph Eron, Myron Cohen, David M Margolis
Published 2010-02-01

Combinatorial latency reversal activity of inhibitor of apoptosis antagonists with mechanistically distinct classes of HIV latency reversal agents

by Shane D. Falcinelli, David M. Irlbeck, Anne-Marie Turner, Frances Potjewyd, Lindsey I. James, David M. Margolis, Nancie M. Archin, Richard M. Dunham
Published 2019-12-01

Peripheral Vγ9Vδ2 T Cells Are a Novel Reservoir of Latent HIV Infection.

by Natalia Soriano-Sarabia, Nancie M Archin, Rosalie Bateson, Noelle P Dahl, Amanda M Crooks, JoAnn D Kuruc, Carolina Garrido, David M Margolis
Published 2015-10-01

Selective HDAC inhibition for the disruption of latent HIV-1 infection.

by Kirston M Barton, Nancie M Archin, Kara S Keedy, Amy S Espeseth, Yan-ling Zhang, Jennifer Gale, Florence F Wagner, Edward B Holson, David M Margolis
Published 2014-01-01

Four Weeks of Treatment With Rifaximin Fails to Significantly Alter Microbial Diversity in Rectal Samples of HIV-Infected Immune Non-Responders (ACTG A5286) Which May be Attributed...

by Brett B. Williams, Stefan J. Green, Ronald J. Bosch, Ellen S. Chan, Jeffrey M. Jacobson, David M. Margolis, Phillip Engen, Alan L. Landay, Cara C. Wilson
Published 2019-09-01

Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells

by Julia A. Sung, Katherine Sholtis, Jennifer Kirchherr, Joann D. Kuruc, Cynthia L. Gay, Jeffrey L. Nordstrom, Catherine M. Bollard, Nancie M. Archin, David M. Margolis
Published 2017-09-01

Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.

by Cory H White, Bastiaan Moesker, Nadejda Beliakova-Bethell, Laura J Martins, Celsa A Spina, David M Margolis, Douglas D Richman, Vicente Planelles, Alberto Bosque, Christopher H Woelk
Published 2016-11-01

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors.

by Stuart R Jefferys, Samuel D Burgos, Jackson J Peterson, Sara R Selitsky, Anne-Marie W Turner, Lindsey I James, Yi-Hsuan Tsai, Alisha R Coffey, David M Margolis, Joel Parker, Edward P Browne
Published 2021-02-01

24 HIV-specific, ex vivo expanded T cell therapy (HXTC) for HIV clearance: feasibility, safety and efficacy

by Julia M. Sung, JoAnnD Kuruc, Matthew Clohosey, Amanda Crooks, Shabnum Patel, Lauren Roesch, Patrick Hanley, CRussell Cruz, Nancie Archin, JosephJ Eron, Nilu Goonetilleke, Cliona M. Rooney, Catherine M. Bollard, David M. Margolis, Cynthia L. Gay
Published 2017-07-01

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

by Alberto Bosque, Kyle A. Nilson, Amanda B. Macedo, Adam M. Spivak, Nancie M. Archin, Ryan M. Van Wagoner, Laura J. Martins, Camille L. Novis, Matthew A. Szaniawski, Chris M. Ireland, David M. Margolis, David H. Price, Vicente Planelles
Published 2017-01-01

HIV-Specific T Cell Responses Are Highly Stable on Antiretroviral Therapy

by Yinyan Xu, Ilana M. Trumble, Joanna A. Warren, Genevieve Clutton, Maria Abad-Fernandez, Jennifer Kirchnerr, Adaora A. Adimora, Steven G. Deeks, David M. Margolis, JoAnn D. Kuruc, Cynthia L. Gay, Nancie M. Archin, Katie R. Mollan, Michael Hudgens, Nilu Goonetilleke
Published 2019-12-01

Correction: The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial.

by Rajesh T. Gandhi, Lu Zheng, Ronald J. Bosch, Ellen S. Chan, David M. Margolis, Sarah Read, Beatrice Kallungal, Sarah Palmer, Kathy Medvik, Michael M. Lederman, Nadia Alatrakchi, Jeffrey M. Jacobson, Ann Wiegand, Mary Kearney, John M. Coffin, John W. Mellors, Joseph J. Eron
Published 2011-08-01

A Cure for HIV Infection: “Not in My Lifetime” or “Just Around the Corner”?

by Michael M. Lederman, Paula M. Cannon, Judith S. Currier, Carl H. June, Hans-Peter Kiem, Daniel R. Kuritzkes, Sharon R. Lewin, David M. Margolis, Joseph M. McCune, John W. Mellors, Timothy W. Schacker, Rafick P. Sekaly, Pablo Tebas, Bruce D. Walker, Daniel C. Douek
Published 2016-08-01