Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer.

by Mark W Zimmerman, Gregg E Homanics, John S Lazo
Published 2013-01-01

Deletion of Ptp4a3 reduces clonogenicity and tumor-initiation ability of colitis-associated cancer cells in mice

by Julie M. Cramer, Mark W. Zimmerman, Tim Thompson, Gregg E. Homanics, John S. Lazo, Eric Lagasse
Published 2014-07-01

Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies.

by Felix Oppel, Ting Tao, Hui Shi, Kenneth N Ross, Mark W Zimmerman, Shuning He, Guangxiang Tong, Jon C Aster, A Thomas Look
Published 2019-04-01

suz12 inactivation in p53- and nf1-deficient zebrafish accelerates the onset of malignant peripheral nerve sheath tumors and expands the spectrum of tumor types

by Felix Oppel, Dong H. Ki, Mark W. Zimmerman, Kenneth N. Ross, Ting Tao, Hui Shi, Shuning He, Jon C. Aster, A. Thomas Look
Published 2020-08-01

Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain

by Shuning He, Marc R Mansour, Mark W Zimmerman, Dong Hyuk Ki, Hillary M Layden, Koshi Akahane, Evisa Gjini, Eric D de Groh, Antonio R Perez-Atayde, Shizhen Zhu, Jonathan A Epstein, A Thomas Look
Published 2016-04-01

ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

by Lu Wang, Tze King Tan, Adam D. Durbin, Mark W. Zimmerman, Brian J. Abraham, Shi Hao Tan, Phuong Cao Thi Ngoc, Nina Weichert-Leahey, Koshi Akahane, Lee N. Lawton, Jo Lynne Rokita, John M. Maris, Richard A. Young, A. Thomas Look, Takaomi Sanda
Published 2019-12-01

Super-enhancer-based identification of a BATF3/IL-2R−module reveals vulnerabilities in anaplastic large cell lymphoma

by Huan-Chang Liang, Mariantonia Costanza, Nicole Prutsch, Mark W. Zimmerman, Elisabeth Gurnhofer, Ivonne A. Montes-Mojarro, Brian J. Abraham, Nina Prokoph, Stefan Stoiber, Simone Tangermann, Cosimo Lobello, Jan Oppelt, Ioannis Anagnostopoulos, Thomas Hielscher, Shahid Pervez, Wolfram Klapper, Francesca Zammarchi, Daniel-Adriano Silva, K. Christopher Garcia, David Baker, Martin Janz, Nikolai Schleussner, Falko Fend, Šárka Pospíšilová, Andrea Janiková, Jacqueline Wallwitz, Dagmar Stoiber, Ingrid Simonitsch-Klupp, Lorenzo Cerroni, Stefano Pileri, Laurence de Leval, David Sibon, Virginie Fataccioli, Philippe Gaulard, Chalid Assaf, Fabian Knörr, Christine Damm-Welk, Wilhelm Woessmann, Suzanne D. Turner, A. Thomas Look, Stephan Mathas, Lukas Kenner, Olaf Merkel
Published 2021-09-01