QT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjects.

by Kumiko Fujii, Yuji Ozeki, Hiroaki Okayasu, Yumiko Takano, Takahiro Shinozaki, Hiroaki Hori, Masami Orui, Minoru Horie, Hiroshi Kunugi, Kazutaka Shimoda
Published 2014-01-01

Left‐dominant arrhythmogenic cardiomyopathy with a nonsense mutation in DSP

by Yuichiro Tsuruta, Daisuke Sueta, Seiji Takashio, Seitaro Oda, Kenij Sakamoto, Koichi Kaikita, Koichi Kato, Seiko Ohno, Minoru Horie, Kenichi Tsujita
Published 2020-10-01

Refractory ventricular fibrillations after surgical repair of atrial septal defects in a patient with CACNA1C gene mutation - case report

by Ai Kojima, Fumiaki Shikata, Toru Okamura, Takashi Higaki, Seiko Ohno, Minoru Horie, Shunji Uchita, Yujiro Kawanishi, Kenji Namiguchi, Takumi Yasugi, Hironori Izutani
Published 2017-12-01

Genetic variants of alcohol‐metabolizing enzymes in Brugada syndrome: Insights into syncope after drinking alcohol

by Qi Wu, Hideki Hayashi, Daiki Hira, Keiko Sonoda, Satoshi Ueshima, Seiko Ohno, Takeru Makiyama, Tomohiro Terada, Toshiya Katsura, Katsuyuki Miura, Minoru Horie
Published 2019-10-01

Propranolol Attenuates Late Sodium Current in a Long QT Syndrome Type 3-Human Induced Pluripotent Stem Cell Model

by Sayako Hirose, Takeru Makiyama, Dario Melgari, Dario Melgari, Yuta Yamamoto, Yuta Yamamoto, Yimin Wuriyanghai, Fumika Yokoi, Suguru Nishiuchi, Takeshi Harita, Mamoru Hayano, Hirohiko Kohjitani, Jingshan Gao, Asami Kashiwa, Misato Nishikawa, Jie Wu, Jie Wu, Jun Yoshimoto, Kazuhisa Chonabayashi, Seiko Ohno, Yoshinori Yoshida, Minoru Horie, Minoru Horie, Takeshi Kimura
Published 2020-08-01

Hydroxyzine, a First Generation H1-Receptor Antagonist, Inhibits Human Ether-a-go-go–Related Gene (HERG) Current and Causes Syncope in a Patient With the HERG Mutation

by Tomoko Sakaguchi, Hideki Itoh, Wei-Guang Ding, Keiko Tsuji, Iori Nagaoka, Yuko Oka, Takashi Ashihara, Makoto Ito, Yoshihiro Yumoto, Naoko Zenda, Yukei Higashi, Youichi Takeyama, Hiroshi Matsuura, Minoru Horie
Published 2008-01-01

Prevalence and QT Interval of Early Repolarization in a Hospital-based Population

by Hideki Hayashi, MD PhD, Akashi Miyamoto, MD, Katsuya Ishida, MD, Tomohide Yoshino, MD, Yoshihisa Sugimoto, MD PhD, Makoto Ito, MD PhD, Minoru Horie, MD PhD
Published 2010-01-01

Phenotype-Based High-Throughput Classification of Long QT Syndrome Subtypes Using Human Induced Pluripotent Stem Cells

by Daisuke Yoshinaga, Shiro Baba, Takeru Makiyama, Hirofumi Shibata, Takuya Hirata, Kentaro Akagi, Koichi Matsuda, Hirohiko Kohjitani, Yimin Wuriyanghai, Katsutsugu Umeda, Yuta Yamamoto, Bruce R. Conklin, Minoru Horie, Junko Takita, Toshio Heike
Published 2019-08-01

Comparison of circadian, weekly, and seasonal variations of electrical storms and single events of ventricular fibrillation in patients with Brugada syndrome

by Yoshiyasu Aizawa, Seiji Takatsuki, Yoshiaki Kaneko, Takashi Noda, Yoshinori Katsumata, Takahiko Nishiyama, Takehiro Kimura, Nobuhiro Nishiyama, Kotaro Fukumoto, Shinichi Niwano, Takashi Kurita, Takeshi Mitsuhashi, Shiro Kamakura, Akihiko Shimizu, Minoru Horie, Yoshifusa Aizawa, Keiichi Fukuda
Published 2016-06-01

Practical applicability of landiolol, an ultra-short-acting β1-selective blocker, for rapid atrial and ventricular tachyarrhythmias with left ventricular dysfunction

by Yuko Wada, Takeshi Aiba, Yasuyuki Tsujita, Hideki Itoh, Mitsuru Wada, Ikutaro Nakajima, Kohei Ishibashi, Hideo Okamura, Koji Miyamoto, Takashi Noda, Yasuo Sugano, Hideaki Kanzaki, Toshihisa Anzai, Kengo Kusano, Satoshi Yasuda, Minoru Horie, Hisao Ogawa
Published 2016-04-01

Carvedilol, a Non-Selective β-with α1-Blocker is Effective in Long QT Syndrome Type 2

by Hiromi Kimura, MD, Yuka Mizusawa, MD, Hideki Itoh, MD, Akashi Miyamoto, MD, Mihoko Kawamura, MD, Tamiro Kawaguchi, MD, Nobu Naiki, MD, Yuko Oka, MD, Seiko Ohno, MD, Takeru Makiyama, MD, Makoto Ito, MD, Minoru Horie, MD
Published 2011-01-01

Flecainide reduces ventricular arrhythmias via a mechanism that differs from that of β-blockers in catecholaminergic polymorphic ventricular tachycardia

by Kenichi Dochi, Hiroshi Watanabe, Mihoko Kawamura, Akashi Miyamoto, Tomoya Ozawa, Yuko Nakazawa, Takashi Ashihara, Seiko Ohno, Hideki Hayashi, Makoto Ito, Hisanori Sakazaki, Hiro Kawata, Hiroya Ushinohama, Richard H. Kaszynski, Tohru Minamino, Naokata Sumitomo, Wataru Shimizu, Minoru Horie
Published 2013-10-01

Genetic screening of KCNJ8 in Japanese patients with J-wave syndromes or idiopathic ventricular fibrillation

by Qi Wang, BSc, Seiko Ohno, MD, PhD, Koichi Kato, MD, Megumi Fukuyama, MD, Takeru Makiyama, MD, PhD, Hiromi Kimura, MD, PhD, Nobu Naiki, MD, Mihoko Kawamura, MD, Hideki Hayashi, MD, PhD, Minoru Horie, MD, PhD
Published 2013-10-01

Smoking, Smoking Cessation, and Measures of Subclinical Atherosclerosis in Multiple Vascular Beds in Japanese Men

by Takashi Hisamatsu, Katsuyuki Miura, Hisatomi Arima, Aya Kadota, Sayaka Kadowaki, Sayuki Torii, Sentaro Suzuki, Naoko Miyagawa, Atsushi Sato, Masahiro Yamazoe, Akira Fujiyoshi, Takayoshi Ohkubo, Takashi Yamamoto, Kiyoshi Murata, Robert D. Abbott, Akira Sekikawa, Minoru Horie, Hirotsugu Ueshima, the Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) Research Group
Published 2016-09-01

Patient-Specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventric...

by Kenichi Sasaki, Takeru Makiyama, Yoshinori Yoshida, Yimin Wuriyanghai, Tsukasa Kamakura, Suguru Nishiuchi, Mamoru Hayano, Takeshi Harita, Yuta Yamamoto, Hirohiko Kohjitani, Sayako Hirose, Jiarong Chen, Mihoko Kawamura, Seiko Ohno, Hideki Itoh, Ayako Takeuchi, Satoshi Matsuoka, Masaru Miura, Naokata Sumitomo, Minoru Horie, Shinya Yamanaka, Takeshi Kimura
Published 2016-01-01

A rare KCNE1 polymorphism, D85N, as a genetic modifier of long QT syndrome

by Kanae Hasegawa, MD, Seiko Ohno, MD, PhD, Hideki Itoh, MD, PhD, Takeru Makiyama, MD, PhD, Takeshi Aiba, MD, PhD, Yasutaka Nakano, MD, PhD, Wataru Shimizu, MD, PhD, Hiroshi Matsuura, MD, PhD, Naomasa Makita, MD, PhD, Minoru Horie, MD, PhD
Published 2014-06-01

Flecainide ameliorates arrhythmogenicity through NCX flux in Andersen-Tawil syndrome-iPS cell-derived cardiomyocytes

by Yusuke Kuroda, Shinsuke Yuasa, Yasuhide Watanabe, Shogo Ito, Toru Egashira, Tomohisa Seki, Tetsuhisa Hattori, Seiko Ohno, Masaki Kodaira, Tomoyuki Suzuki, Hisayuki Hashimoto, Shinichiro Okata, Atsushi Tanaka, Yoshiyasu Aizawa, Mitsushige Murata, Takeshi Aiba, Naomasa Makita, Tetsushi Furukawa, Wataru Shimizu, Itsuo Kodama, Satoshi Ogawa, Norito Kokubun, Hitoshi Horigome, Minoru Horie, Kaichiro Kamiya, Keiichi Fukuda
Published 2017-03-01

A nonsynonymous polymorphism in semaphorin 3A as a risk factor for human unexplained cardiac arrest with documented ventricular fibrillation.

by Yukiko Nakano, Kazuaki Chayama, Hidenori Ochi, Masaaki Toshishige, Yasufumi Hayashida, Daiki Miki, C Nelson Hayes, Hidekazu Suzuki, Takehito Tokuyama, Noboru Oda, Kazuyoshi Suenari, Yuko Uchimura-Makita, Kenta Kajihara, Akinori Sairaku, Chikaaki Motoda, Mai Fujiwara, Yoshikazu Watanabe, Yukihiko Yoshida, Kimie Ohkubo, Ichiro Watanabe, Akihiko Nogami, Kanae Hasegawa, Hiroshi Watanabe, Naoto Endo, Takeshi Aiba, Wataru Shimizu, Seiko Ohno, Minoru Horie, Koji Arihiro, Satoshi Tashiro, Naomasa Makita, Yasuki Kihara
Published 2013-04-01

Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes

by Nobue Yagihara, Hiroshi Watanabe, Phil Barnett, Laetitia Duboscq‐Bidot, Atack C. Thomas, Ping Yang, Seiko Ohno, Kanae Hasegawa, Ryozo Kuwano, Stéphanie Chatel, Richard Redon, Jean‐Jacques Schott, Vincent Probst, Tamara T. Koopmann, Connie R. Bezzina, Arthur A. M. Wilde, Yukiko Nakano, Takeshi Aiba, Yoshihiro Miyamoto, Shiro Kamakura, Dawood Darbar, Brian S. Donahue, Daichi Shigemizu, Toshihiro Tanaka, Tatsuhiko Tsunoda, Masayoshi Suda, Akinori Sato, Tohru Minamino, Naoto Endo, Wataru Shimizu, Minoru Horie, Dan M. Roden, Naomasa Makita
Published 2016-09-01

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

by Charles Antzelevitch, PhD, FHRS, Gan-Xin Yan, MD, PhD, Michael J. Ackerman, MD, PhD, Martin Borggrefe, MD, Domenico Corrado, MD, PhD, Jihong Guo, MD, Ihor Gussak, MD, PhD, Can Hasdemir, MD, Minoru Horie, MD, Heikki Huikuri, MD, Changsheng Ma, MD, Hiroshi Morita, MD, PhD, Gi-Byoung Nam, MD, PhD, Frederic Sacher, MD, PhD, Wataru Shimizu, MD, PhD, Sami Viskin, MD, Arthur A.M. Wilde, MD, PhD, FHRS
Published 2016-10-01