Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M

by Asami Kashiwa, Yukio Hosaka, Kazuyoshi Takahashi, Seiko Ohno, Yuko Wada, Takeru Makiyama, Hirotaka Oda, Minoru Horie
Published 2021-08-01

A Novel SCN5A Mutation Associated with Drug Induced Brugada Type ECG.

by Isik Turker, Takeru Makiyama, Matteo Vatta, Hideki Itoh, Takeshi Ueyama, Akihiko Shimizu, Tomohiko Ai, Minoru Horie
Published 2016-01-01

Erratum to “Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patient...

by Tadashi Takaki, Azusa Inagaki, Kazuhisa Chonabayashi, Keiji Inoue, Kenji Miki, Seiko Ohno, Takeru Makiyama, Minoru Horie, Yoshinori Yoshida
Published 2020-01-01

Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients

by Tadashi Takaki, Azusa Inagaki, Kazuhisa Chonabayashi, Keiji Inoue, Kenji Miki, Seiko Ohno, Takeru Makiyama, Minoru Horie, Yoshinori Yoshida
Published 2019-01-01

Cardiac conduction defects and Brugada syndrome: A family with overlap syndrome carrying a nonsense SCN5A mutation

by Hisaaki Aoki, MD, PHD, Yoshihide Nakamura, MD, Seiko Ohno, MD, PHD, Takeru Makiyama, MD, PHD, Minoru Horie, MD, PHD
Published 2017-02-01

Genetic variants of alcohol‐metabolizing enzymes in Brugada syndrome: Insights into syncope after drinking alcohol

by Qi Wu, Hideki Hayashi, Daiki Hira, Keiko Sonoda, Satoshi Ueshima, Seiko Ohno, Takeru Makiyama, Tomohiro Terada, Toshiya Katsura, Katsuyuki Miura, Minoru Horie
Published 2019-10-01

Phenotype-Based High-Throughput Classification of Long QT Syndrome Subtypes Using Human Induced Pluripotent Stem Cells

by Daisuke Yoshinaga, Shiro Baba, Takeru Makiyama, Hirofumi Shibata, Takuya Hirata, Kentaro Akagi, Koichi Matsuda, Hirohiko Kohjitani, Yimin Wuriyanghai, Katsutsugu Umeda, Yuta Yamamoto, Bruce R. Conklin, Minoru Horie, Junko Takita, Toshio Heike
Published 2019-08-01

Carvedilol, a Non-Selective β-with α1-Blocker is Effective in Long QT Syndrome Type 2

by Hiromi Kimura, MD, Yuka Mizusawa, MD, Hideki Itoh, MD, Akashi Miyamoto, MD, Mihoko Kawamura, MD, Tamiro Kawaguchi, MD, Nobu Naiki, MD, Yuko Oka, MD, Seiko Ohno, MD, Takeru Makiyama, MD, Makoto Ito, MD, Minoru Horie, MD
Published 2011-01-01

Genetic screening of KCNJ8 in Japanese patients with J-wave syndromes or idiopathic ventricular fibrillation

by Qi Wang, BSc, Seiko Ohno, MD, PhD, Koichi Kato, MD, Megumi Fukuyama, MD, Takeru Makiyama, MD, PhD, Hiromi Kimura, MD, PhD, Nobu Naiki, MD, Mihoko Kawamura, MD, Hideki Hayashi, MD, PhD, Minoru Horie, MD, PhD
Published 2013-10-01

Patient-Specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventric...

by Kenichi Sasaki, Takeru Makiyama, Yoshinori Yoshida, Yimin Wuriyanghai, Tsukasa Kamakura, Suguru Nishiuchi, Mamoru Hayano, Takeshi Harita, Yuta Yamamoto, Hirohiko Kohjitani, Sayako Hirose, Jiarong Chen, Mihoko Kawamura, Seiko Ohno, Hideki Itoh, Ayako Takeuchi, Satoshi Matsuoka, Masaru Miura, Naokata Sumitomo, Minoru Horie, Shinya Yamanaka, Takeshi Kimura
Published 2016-01-01

Propranolol Attenuates Late Sodium Current in a Long QT Syndrome Type 3-Human Induced Pluripotent Stem Cell Model

by Sayako Hirose, Takeru Makiyama, Dario Melgari, Dario Melgari, Yuta Yamamoto, Yuta Yamamoto, Yimin Wuriyanghai, Fumika Yokoi, Suguru Nishiuchi, Takeshi Harita, Mamoru Hayano, Hirohiko Kohjitani, Jingshan Gao, Asami Kashiwa, Misato Nishikawa, Jie Wu, Jie Wu, Jun Yoshimoto, Kazuhisa Chonabayashi, Seiko Ohno, Yoshinori Yoshida, Minoru Horie, Minoru Horie, Takeshi Kimura
Published 2020-08-01

A rare KCNE1 polymorphism, D85N, as a genetic modifier of long QT syndrome

by Kanae Hasegawa, MD, Seiko Ohno, MD, PhD, Hideki Itoh, MD, PhD, Takeru Makiyama, MD, PhD, Takeshi Aiba, MD, PhD, Yasutaka Nakano, MD, PhD, Wataru Shimizu, MD, PhD, Hiroshi Matsuura, MD, PhD, Naomasa Makita, MD, PhD, Minoru Horie, MD, PhD
Published 2014-06-01