The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results from the TULIP and METSIM Studies.

by Peter Weyrich, Harald Staiger, Alena Stančáková, Fausto Machicao, Jürgen Machann, Fritz Schick, Norbert Stefan, Johanna Kuusisto, Markku Laakso, Silke Schäfer, Andreas Fritsche, Hans-Ulrich Häring
Published 2010-01-01

Heterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) gene and metabolic risk factors in the EPIC-Potsdam study.

by Maria Arregui, Brian Buijsse, Norbert Stefan, Dolores Corella, Eva Fisher, Romina di Giuseppe, Oscar Coltell, Sven Knüppel, Krasimira Aleksandrova, Hans-Georg Joost, Heiner Boeing, Cornelia Weikert
Published 2012-01-01

Normalized Indices Derived from Visceral Adipose Mass Assessed by Magnetic Resonance Imaging and Their Correlation with Markers for Insulin Resistance and Prediabetes

by Jürgen Machann, Norbert Stefan, Robert Wagner, Andreas Fritsche, Jimmy D. Bell, Brandon Whitcher, Hans-Ulrich Häring, Andreas L. Birkenfeld, Konstantin Nikolaou, Fritz Schick, E. Louise Thomas
Published 2020-07-01

Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers.

by Martin Kächele, Anita M Hennige, Jürgen Machann, Anja Hieronimus, Apostolia Lamprinou, Fausto Machicao, Fritz Schick, Andreas Fritsche, Norbert Stefan, Bernd Nürnberg, Hans-Ulrich Häring, Harald Staiger
Published 2015-01-01

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipo...

by Lucia Berti, Martin Irmler, Marty Zdichavsky, Tobias Meile, Anja Böhm, Norbert Stefan, Andreas Fritsche, Johannes Beckers, Alfred Königsrainer, Hans-Ulrich Häring, Martin Hrabě de Angelis, Harald Staiger
Published 2015-07-01

Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease

by Christian Baumeier, Luisa Schlüter, Sophie Saussenthaler, Thomas Laeger, Maria Rödiger, Stella Amelie Alaze, Louise Fritsche, Hans-Ulrich Häring, Norbert Stefan, Andreas Fritsche, Robert Wolfgang Schwenk, Annette Schürmann
Published 2017-10-01

Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content.

by Fausto Machicao, Andreas Peter, Jürgen Machann, Ingmar Königsrainer, Anja Böhm, Stefan Zoltan Lutz, Martin Heni, Andreas Fritsche, Fritz Schick, Alfred Königsrainer, Norbert Stefan, Hans-Ulrich Häring, Harald Staiger
Published 2016-01-01

Reduced insulin clearance is linked to subclinical atherosclerosis in individuals at risk for type 2 diabetes mellitus

by Elko Randrianarisoa, Angela Lehn-Stefan, Anja Hieronimus, Robert Wagner, Jakob Maucher, Kilian Rittig, Bernd Balletshofer, Andreas L. Birkenfeld, Andreas Peter, Norbert Stefan, Hans-Ulrich Häring, Andreas Fritsche, Martin Heni
Published 2020-12-01

Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans.

by Tina Sartorius, Harald Staiger, Caroline Ketterer, Martin Heni, Fausto Machicao, Adilson Guilherme, Harald Grallert, Matthias B Schulze, Heiner Boeing, Norbert Stefan, Andreas Fritsche, Michael P Czech, Hans-Ulrich Häring
Published 2012-01-01

Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity.

by Harald Staiger, Anja Böhm, Mika Scheler, Lucia Berti, Jürgen Machann, Fritz Schick, Fausto Machicao, Andreas Fritsche, Norbert Stefan, Cora Weigert, Anna Krook, Hans-Ulrich Häring, Martin Hrabě de Angelis
Published 2013-01-01

Metabolic signatures of cultured human adipocytes from metabolically healthy versus unhealthy obese individuals.

by Anja Böhm, Anna Halama, Tobias Meile, Marty Zdichavsky, Rainer Lehmann, Cora Weigert, Andreas Fritsche, Norbert Stefan, Alfred Königsrainer, Hans-Ulrich Häring, Martin Hrabě de Angelis, Jerzy Adamski, Harald Staiger
Published 2014-01-01

Impact of the adipokine adiponectin and the hepatokine fetuin-A on the development of type 2 diabetes: prospective cohort- and cross-sectional phenotyping studies.

by Norbert Stefan, Qi Sun, Andreas Fritsche, Jürgen Machann, Fritz Schick, Felicia Gerst, Charlotte Jeppesen, Hans-Georg Joost, Frank B Hu, Heiner Boeing, Susanne Ullrich, Hans-Ulrich Häring, Matthias B Schulze
Published 2014-01-01

Free fatty acids, glicentin and glucose-dependent insulinotropic polypeptide as potential major determinants of fasting substrate oxidation

by Julia Hummel, Louise Fritsche, Andreas Vosseler, Corinna Dannecker, Miriam Hoene, Konstantinos Kantartzis, Hans-Ulrich Häring, Norbert Stefan, Jürgen Machann, Andreas L. Birkenfeld, Cora Weigert, Robert Wagner, Andreas Peter, Andreas Fritsche, Martin Heni
Published 2021-08-01

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.

by Trine Welløv Boesgaard, Anette Prior Gjesing, Niels Grarup, Jarno Rutanen, Per-Anders Jansson, Marta Letizia Hribal, Giorgio Sesti, Andreas Fritsche, Norbert Stefan, Harald Staiger, Hans Häring, Ulf Smith, Markku Laakso, Oluf Pedersen, Torben Hansen, EUGENE2 Consortium
Published 2009-09-01

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

by Björn Friedrich, Peter Weyrich, Alena Stancáková, Jianjung Wang, Johanna Kuusisto, Markku Laakso, Giorgio Sesti, Elena Succurro, Ulf Smith, Torben Hansen, Oluf Pedersen, Fausto Machicao, Silke Schäfer, Florian Lang, Teut Risler, Susanne Ullrich, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring
Published 2008-01-01