A genotype-phenotype screening system using conditionally immortalized immature dendritic cells

by Liwei Zhao, Peng Liu, Wei Xie, Shuai Zhang, Sebastian Thieme, Laurence Zitvogel, Guido Kroemer, Oliver Kepp
Published 2021-09-01

Lysosomotropic agents including azithromycin, chloroquine and hydroxychloroquine activate the integrated stress response

by Ai-Ling Tian, Qi Wu, Peng Liu, Liwei Zhao, Isabelle Martins, Oliver Kepp, Marion Leduc, Guido Kroemer
Published 2021-01-01

Trial watch: Peptide-based vaccines in anticancer therapy

by Lucillia Bezu, Oliver Kepp, Giulia Cerrato, Jonathan Pol, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi
Published 2018-12-01

Anticancer effects of anti-CD47 immunotherapy in vivo

by Kristina Iribarren, Aitziber Buque, Laura Mondragon, Wei Xie, Sarah Lévesque, Jonathan Pol, Laurence Zitvogel, Oliver Kepp, Guido Kroemer
Published 2019-03-01

Pharmacological inhibitors of anaplastic lymphoma kinase (ALK) induce immunogenic cell death through on-target effects

by Adriana Petrazzuolo, Maria Perez-Lanzon, Isabelle Martins, Peng Liu, Oliver Kepp, Véronique Minard-Colin, Maria Chiara Maiuri, Guido Kroemer
Published 2021-07-01

Detection of immunogenic cell death and its relevance for cancer therapy

by Jitka Fucikova, Oliver Kepp, Lenka Kasikova, Giulia Petroni, Takahiro Yamazaki, Peng Liu, Liwei Zhao, Radek Spisek, Guido Kroemer, Lorenzo Galluzzi
Published 2020-11-01

A fluorescent biosensor-based platform for the discovery of immunogenic cancer cell death inducers

by Oliver Kepp, Allan Sauvat, Marion Leduc, Sabrina Forveille, Peng Liu, Liwei Zhao, Lucillia Bezu, Wei Xie, Laurence Zitvogel, Guido Kroemer
Published 2019-08-01

Combination treatments with hydroxychloroquine and azithromycin are compatible with the therapeutic induction of anticancer immune responses

by Peng Liu, Liwei Zhao, Gladys Ferrere, Carolina Alves-Costa-Silva, Pierre Ly, Qi Wu, Ai-Ling Tian, Lisa Derosa, Laurence Zitvogel, Oliver Kepp, Guido Kroemer
Published 2020-01-01

Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity

by Wei Xie, Sabrina Forveille, Kristina Iribarren, Allan Sauvat, Laura Senovilla, Yan Wang, Juliette Humeau, Maria Perez-Lanzon, Heng Zhou, Juan F. Martínez-Leal, Guido Kroemer, Oliver Kepp
Published 2019-11-01

Helicobacter pylori VacA toxin/subunit p34: targeting of an anion channel to the inner mitochondrial membrane.

by Grazyna Domańska, Christian Motz, Michael Meinecke, Anke Harsman, Panagiotis Papatheodorou, Boris Reljic, Elke A Dian-Lothrop, Antoine Galmiche, Oliver Kepp, Lars Becker, Kathrin Günnewig, Richard Wagner, Joachim Rassow
Published 2010-04-01

Trial watch: Immune checkpoint blockers for cancer therapy

by Claire Vanpouille-Box, Claire Lhuillier, Lucillia Bezu, Fernando Aranda, Takahiro Yamazaki, Oliver Kepp, Jitka Fucikova, Radek Spisek, Sandra Demaria, Silvia C. Formenti, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi
Published 2017-11-01

Tumor lysis with LTX-401 creates anticancer immunity

by Wei Xie, Laura Mondragón, Brynjar Mauseth, Yan Wang, Jonathan Pol, Sarah Lévesque, Heng Zhou, Takahiro Yamazaki, Johannes J. Eksteen, Laurence Zitvogel, Baldur Sveinbjørnsson, Øystein Rekdal, Oliver Kepp, Guido Kroemer
Published 2019-07-01

Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress

by Juliette Humeau, Allan Sauvat, Giulia Cerrato, Wei Xie, Friedemann Loos, Francesca Iannantuoni, Lucillia Bezu, Sarah Lévesque, Juliette Paillet, Jonathan Pol, Marion Leduc, Laurence Zitvogel, Hugues de Thé, Oliver Kepp, Guido Kroemer
Published 2020-05-01

Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids

by Allan Sauvat, Guo Chen, Kevin Müller, Mingming Tong, Fanny Aprahamian, Sylvère Durand, Giulia Cerrato, Lucillia Bezu, Marion Leduc, Joakim Franz, Patrick Rockenfeller, Junichi Sadoshima, Frank Madeo, Oliver Kepp, Guido Kroemer
Published 2018-04-01

IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms−

by Qi Wu, Shuai Zhang, Peng Liu, Wei Xie, Oliver Kepp, Bei Li, Pan Hui, Ai-Ling Tian, Marion Leduc, Sabrina Forveille, Peter Hamley, Warren Galloway, Liwei Zhao, Frank Madeo, Yi Tu
Published 2021-06-01

Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells

by Marion Dajon, Kristina Iribarren, Florent Petitprez, Solenne Marmier, Audrey Lupo, Mélanie Gillard, Hanane Ouakrim, Navas Victor, Di Bartolo Vincenzo, Pierre Emmanuel Joubert, Oliver Kepp, Guido Kroemer, Marco Alifano, Diane Damotte, Isabelle Cremer
Published 2019-01-01

Targeting GATA transcription factors – a novel strategy for anti-aging interventions?

by Andreas Zimmermann, Katharina Kainz, Sebastian J. Hofer, Maria A. Bauer, Sabrina Schroeder, Jörn Dengjel, Federico Pietrocola, Oliver Kepp, Christoph Ruckenstuhl, Tobias Eisenberg, Stephan J. Sigrist, Frank Madeo, Guido Kroemer, Didac Carmona-Gutierrez
Published 2019-05-01

Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis.

by Vera Kozjak-Pavlovic, Elke A Dian-Lothrop, Michael Meinecke, Oliver Kepp, Katharina Ross, Krishnaraj Rajalingam, Anke Harsman, Eva Hauf, Volker Brinkmann, Dirk Günther, Ines Herrmann, Robert Hurwitz, Joachim Rassow, Richard Wagner, Thomas Rudel
Published 2009-10-01

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

by Guo Chen, Wei Xie, Jihoon Nah, Allan Sauvat, Peng Liu, Federico Pietrocola, Valentina Sica, Didac Carmona‐Gutierrez, Andreas Zimmermann, Tobias Pendl, Jelena Tadic, Martina Bergmann, Sebastian J Hofer, Lana Domuz, Sylvie Lachkar, Maria Markaki, Nektarios Tavernarakis, Junichi Sadoshima, Frank Madeo, Oliver Kepp, Guido Kroemer
Published 2019-11-01

Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors

by Romain Daillère, Bertrand Routy, Anne-Gaëlle Goubet, Alexandria Cogdill, Gladys Ferrere, Carolina Alves-Costa Silva, Aurélie Fluckiger, Pierre Ly, Yacine Haddad, Eugenie Pizzato, Cassandra Thelemaque, Marine Fidelle, Marine Mazzenga, Maria Paula Roberti, Cléa Melenotte, Peng Liu, Safae Terrisse, Oliver Kepp, Guido Kroemer, Laurence Zitvogel, Lisa Derosa
Published 2020-01-01