Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions

by Nadezda Apostolova, Francesca Iannantuoni, Aleksandra Gruevska, Jordi Muntane, Milagros Rocha, Victor M. Victor
Published 2020-07-01

Mitochondrial DNA Haplogroup JT is Related to Impaired Glycaemic Control and Renal Function in Type 2 Diabetic Patients

by Noelia Diaz-Morales, Sandra Lopez-Domenech, Francesca Iannantuoni, Ester Lopez-Gallardo, Eva Sola, Carlos Morillas, Milagros Rocha, Eduardo Ruiz-Pesini, Victor M. Victor
Published 2018-08-01

Mitochondrial Alterations and Enhanced Human Leukocyte/Endothelial Cell Interactions in Type 1 Diabetes

by Francesca Iannantuoni, Aranzazu M. de Marañon, Zaida Abad-Jiménez, Francisco Canet, Pedro Díaz-Pozo, Sandra López-Domènech, Carlos Morillas, Milagros Rocha, Víctor M. Víctor
Published 2020-07-01

Systemic Oxidative Stress and Visceral Adipose Tissue Mediators of NLRP3 Inflammasome and Autophagy Are Reduced in Obese Type 2 Diabetic Patients Treated with Metformin

by Zaida Abad-Jiménez, Sandra López-Domènech, Rubén Díaz-Rúa, Francesca Iannantuoni, Segundo Ángel Gómez-Abril, Dolores Periañez-Gómez, Carlos Morillas, Víctor M. Víctor, Milagros Rocha
Published 2020-09-01

The SGLT2 Inhibitor Empagliflozin Ameliorates the Inflammatory Profile in Type 2 Diabetic Patients and Promotes an Antioxidant Response in Leukocytes

by Francesca Iannantuoni, Aranzazu M. de Marañon, Noelia Diaz-Morales, Rosa Falcon, Celia Bañuls, Zaida Abad-Jimenez, Victor M. Victor, Antonio Hernandez-Mijares, Susana Rovira-Llopis
Published 2019-11-01

The Mitochondrial Antioxidant SS-31 Modulates Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Type 2 Diabetes

by Irene Escribano-López, Aranzazu M de Marañon, Francesca Iannantuoni, Sandra López-Domènech, Zaida Abad-Jiménez, Pedro Díaz, Eva Solá, Nadezda Apostolova, Milagros Rocha, Víctor M Víctor
Published 2019-08-01

The Mitochondria-Targeted Antioxidant MitoQ Modulates Mitochondrial Function and Endoplasmic Reticulum Stress in Pancreatic β Cells Exposed to Hyperglycaemia

by Irene Escribano-Lopez, Celia Bañuls, Noelia Diaz-Morales, Francesca Iannantuoni, Susana Rovira-Llopis, Ramon Gomis, Milagros Rocha, Antonio Hernandez-Mijares, Michael P. Murphy, Victor M. Victor
Published 2019-02-01

Association between Proinflammatory Markers, Leukocyte–Endothelium Interactions, and Carotid Intima–Media Thickness in Type 2 Diabetes: Role of Glycemic Control

by Aranzazu Martinez de Marañón, Francesca Iannantuoni, Zaida Abad-Jiménez, Francisco Canet, Pedro Díaz-Pozo, Sandra López-Domènech, Ildefonso Roldán-Torres, Carlos Morillas, Milagros Rocha, Víctor M. Víctor
Published 2020-08-01

Downregulation of miR-31 in Diabetic Nephropathy and its Relationship with Inflammation

by Susana Rovira-Llopis, Irene Escribano-Lopez, Noelia Diaz-Morales, Francesca Iannantuoni, Sandra Lopez-Domenech, Isabel Andújar, Ana Jover, Jonay Pantoja, Luis M. Pallardo, Celia Bañuls, Victor M. Victor
Published 2018-10-01

Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress

by Juliette Humeau, Allan Sauvat, Giulia Cerrato, Wei Xie, Friedemann Loos, Francesca Iannantuoni, Lucillia Bezu, Sarah Lévesque, Juliette Paillet, Jonathan Pol, Marion Leduc, Laurence Zitvogel, Hugues de Thé, Oliver Kepp, Guido Kroemer
Published 2020-05-01

Relationship between PMN-endothelium interactions, ROS production and Beclin-1 in type 2 diabetes

by Aranzazu M. De Marañon, Francesca Iannantuoni, Zaida Abad-Jiménez, Francisco Canet, Pedro Díaz-Pozo, Sandra López-Domènech, Ana Jover, Carlos Morillas, Guillermo Mariño, Nadezda Apostolova, Milagros Rocha, Victor M. Victor
Published 2020-07-01

Characterization of Differentially Expressed Circulating miRNAs in Metabolically Healthy versus Unhealthy Obesity

by Susana Rovira-Llopis, Rubén Díaz-Rúa, Carmen Grau-del Valle, Francesca Iannantuoni, Zaida Abad-Jimenez, Neus Bosch-Sierra, Joaquín Panadero-Romero, Víctor M. Victor, Milagros Rocha, Carlos Morillas, Celia Bañuls
Published 2021-03-01

The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes

by Irene Escribano-Lopez, Noelia Diaz-Morales, Francesca Iannantuoni, Sandra Lopez-Domenech, Aranzazu M de Marañon, Zaida Abad-Jimenez, Celia Bañuls, Susana Rovira-Llopis, Jose R Herance, Milagros Rocha, Victor M Victor
Published 2018-10-01

Does Empagliflozin Modulate Leukocyte–Endothelium Interactions, Oxidative Stress, and Inflammation in Type 2 Diabetes?

by Francisco Canet, Francesca Iannantuoni, Aránzazu Martínez de Marañon, Pedro Díaz-Pozo, Sandra López-Domènech, Teresa Vezza, Blanca Navarro, Eva Solá, Rosa Falcón, Celia Bañuls, Carlos Morillas, Milagros Rocha, Víctor M. Víctor
Published 2021-07-01

Relationship between Oxidative Stress, ER Stress, and Inflammation in Type 2 Diabetes: The Battle Continues

by Estefania Burgos-Morón, Zaida Abad-Jiménez, Aranzazu Martínez de Marañón, Francesca Iannantuoni, Irene Escribano-López, Sandra López-Domènech, Christian Salom, Ana Jover, Vicente Mora, Ildefonso Roldan, Eva Solá, Milagros Rocha, Víctor M. Víctor
Published 2019-09-01