Desaturase Activity and the Risk of Type 2 Diabetes and Coronary Artery Disease: A Mendelian Randomization Study

by Susanne Jäger, Rafael Cuadrat, Per Hoffmann, Clemens Wittenbecher, Matthias B. Schulze
Published 2020-07-01

Risk prediction for coronary heart disease by a genetic risk score - results from the Heinz Nixdorf Recall study

by Sonali Pechlivanis, Nils Lehmann, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Raimund Erbel, Susanne Moebus
Published 2020-09-01

Mendelian Randomization Study on Amino Acid Metabolism Suggests Tyrosine as Causal Trait for Type 2 Diabetes

by Susanne Jäger, Rafael Cuadrat, Clemens Wittenbecher, Anna Floegel, Per Hoffmann, Cornelia Prehn, Jerzy Adamski, Tobias Pischon, Matthias B. Schulze
Published 2020-12-01

Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients

by Leoni Grossmann, Cristine Marie Yde Ohki, Christian Döring, Per Hoffmann, Stefan Herms, Anna Maria Werling, Susanne Walitza, Edna Grünblatt
Published 2021-05-01

Generation of integration-free induced pluripotent stem cells from healthy individuals

by Cristine Marie Yde Ohki, Leoni Grossmann, Christian Döring, Per Hoffmann, Stefan Herms, Anna Maria Werling, Susanne Walitza, Edna Grünblatt
Published 2021-05-01

Generation of human induced pluripotent stem cell lines (hiPSC) from one bipolar disorder patient carrier of a DGKH risk haplotype and one non-risk-variant-carrier bipolar disorder...

by Viola Stella Palladino, Nadia Omega Cipta Subrata, Andreas Geburtig-Chiocchetti, Rhiannon McNeill, Per Hoffmann, Andreas Reif, Sarah Kittel-Schneider
Published 2018-10-01

BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma.

by Daniel Nettersheim, Sina Jostes, Rakesh Sharma, Simon Schneider, Andrea Hofmann, Humberto J Ferreira, Per Hoffmann, Glen Kristiansen, Manel B Esteller, Hubert Schorle
Published 2015-07-01

Association between lipoprotein(a) (Lp(a)) levels and Lp(a) genetic variants with coronary artery calcification

by Sonali Pechlivanis, Amir A. Mahabadi, Per Hoffmann, Markus M. Nöthen, Martina Broecker-Preuss, Raimund Erbel, Susanne Moebus, Andreas Stang, Karl-Heinz Jöckel
Published 2020-03-01

Levetiracetam resistance: Synaptic signatures & corresponding promoter SNPs in epileptic hippocampi

by Tanja Grimminger, Katharina Pernhorst, Rainer Surges, Pitt Niehusmann, Lutz Priebe, Marec von Lehe, Per Hoffmann, Sven Cichon, Susanne Schoch, Albert J. Becker
Published 2013-12-01

Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells

by Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner
Published 2013-01-01

Genetic risk scores for coronary artery disease and its traditional risk factors: Their role in the progression of coronary artery calcification-Results of the Heinz Nixdorf Recall...

by Sonali Pechlivanis, Susanne Moebus, Nils Lehmann, Raimund Erbel, Amir A Mahabadi, Per Hoffmann, Karl-Heinz Jöckel, Markus M Nöthen, Hagen S Bachmann, Heinz Nixdorf Recall Study Investigative Group
Published 2020-01-01

Evidence of Inbreeding in Hodgkin Lymphoma.

by Hauke Thomsen, Miguel Inacio da Silva Filho, Michael Fuchs, Sabine Ponader, Elke Pogge von Strandmann, Lewin Eisele, Stefan Herms, Per Hoffmann, Andreas Engert, Kari Hemminki, Asta Försti
Published 2016-01-01

Systematic pathway enrichment analysis of a genome-wide association study on breast cancer survival reveals an influence of genes involved in cell adhesion and calcium signaling on...

by Andrea Woltmann, Bowang Chen, Jesús Lascorz, Robert Johansson, Jorunn E Eyfjörd, Ute Hamann, Jonas Manjer, Kerstin Enquist-Olsson, Roger Henriksson, Stefan Herms, Per Hoffmann, Kari Hemminki, Per Lenner, Asta Försti
Published 2014-01-01

DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations

by Yasmeen Niazi, Yasmeen Niazi, Yasmeen Niazi, Hauke Thomsen, Hauke Thomsen, Bozena Smolkova, Ludmila Vodickova, Ludmila Vodickova, Ludmila Vodickova, Sona Vodenkova, Michal Kroupa, Michal Kroupa, Veronika Vymetalkova, Veronika Vymetalkova, Veronika Vymetalkova, Alena Kazimirova, Magdalena Barancokova, Katarina Volkovova, Marta Staruchova, Per Hoffmann, Per Hoffmann, Markus M. Nöthen, Maria Dusinska, Ludovit Musak, Pavel Vodicka, Pavel Vodicka, Pavel Vodicka, Kari Hemminki, Kari Hemminki, Kari Hemminki, Asta Försti, Asta Försti, Asta Försti
Published 2021-06-01

Identification of pleiotropy at the gene level between psychiatric disorders and related traits

by Tatiana Polushina, Niladri Banerjee, Sudheer Giddaluru, Francesco Bettella, Thomas Espeseth, Astri J. Lundervold, Srdjan Djurovic, Sven Cichon, Per Hoffmann, Markus M. Nöthen, Vidar M. Steen, Ole A. Andreassen, Stéphanie Le Hellard
Published 2021-07-01

Energy Metabolism Disturbances in Cell Models of PARK2 CNV Carriers with ADHD

by Viola Stella Palladino, Andreas G. Chiocchetti, Lukas Frank, Denise Haslinger, Rhiannon McNeill, Franziska Radtke, Andreas Till, Simone Haupt, Oliver Brüstle, Katharina Günther, Frank Edenhofer, Per Hoffmann, Andreas Reif, Sarah Kittel-Schneider
Published 2020-12-01

Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function

by Christopher Schröder, Elsa Leitão, Stefan Wallner, Gerd Schmitz, Ludger Klein-Hitpass, Anupam Sinha, Karl-Heinz Jöckel, Stefanie Heilmann-Heimbach, Per Hoffmann, Markus M. Nöthen, Michael Steffens, Peter Ebert, Sven Rahmann, Bernhard Horsthemke
Published 2017-07-01

Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells

by Eduardo Fernandez-Rebollo, Birgit Mentrup, Regina Ebert, Julia Franzen, Giulio Abagnale, Torsten Sieben, Alina Ostrowska, Per Hoffmann, Pierre-François Roux, Björn Rath, Michele Goodhardt, Jean-Marc Lemaitre, Oliver Bischof, Franz Jakob, Wolfgang Wagner
Published 2017-07-01

Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study

by Subhayan Chattopadhyay, Hauke Thomsen, Miguel Inacio da Silva Filho, Niels Weinhold, Per Hoffmann, Markus M. Nöthen, Arendt Marina, Karl-Heinz Jöckel, Börge Schmidt, Sonali Pechlivanis, Christian Langer, Hartmut Goldschmidt, Kari Hemminki, Asta Försti
Published 2018-06-01

Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS)

by Sukanya Horpaopan, Jutta Kirfel, Sophia Peters, Michael Kloth, Robert Hüneburg, Janine Altmüller, Dmitriy Drichel, Margarete Odenthal, Glen Kristiansen, Christian Strassburg, Jacob Nattermann, Per Hoffmann, Peter Nürnberg, Reinhard Büttner, Holger Thiele, Philip Kahl, Isabel Spier, Stefan Aretz
Published 2017-11-01