NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy

by Naoki Watanabe, Tetsuya Nagata, Youhei Satou, Satoru Masuda, Takashi Saito, Hidetoshi Kitagawa, Hirofumi Komaki, Kazuchika Takagaki, Shin’ichi Takeda
Published 2018-12-01

Accelerometric outcomes of motor function related to clinical evaluations and muscle involvement in dystrophic dogs.

by Mutsuki Kuraoka, Yuko Nitahara-Kasahara, Hisateru Tachimori, Naohiro Kato, Hiroyuki Shibasaki, Akihiko Shin, Yoshitsugu Aoki, En Kimura, Shin'ichi Takeda
Published 2018-01-01

Characterization of a novel microRNA, miR-188, elevated in serum of muscular dystrophy dog model.

by Hiroyuki Shibasaki, Michihiro Imamura, Sayuri Arima, Jun Tanihata, Mutsuki Kuraoka, Yasunari Matsuzaka, Fumiaki Uchiumi, Sei-Ichi Tanuma, Shin'ichi Takeda
Published 2019-01-01

Improved transduction of canine X-linked muscular dystrophy with rAAV9-microdystrophin via multipotent MSC pretreatment

by Hiromi Hayashita-Kinoh, Posadas-Herrera Guillermo, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Hironori Okada, Tomoko Chiyo, Shin’ichi Takeda, Takashi Okada
Published 2021-03-01

iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin

by Ken’ichiro Nogami, Yusuke Maruyama, Ahmed Elhussieny, Fusako Sakai-Takemura, Jun Tanihata, Jun-ichi Kira, Yuko Miyagoe-Suzuki, Shin’ichi Takeda
Published 2020-07-01

Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot

by Hitoshi Suzuki, Yoshitsugu Aoki, Toshiki Kameyama, Takashi Saito, Satoru Masuda, Jun Tanihata, Tetsuya Nagata, Akila Mayeda, Shin’ichi Takeda, Toshifumi Tsukahara
Published 2016-10-01

Robust Long-term Transduction of Common Marmoset Neuromuscular Tissue With rAAV1 and rAAV9

by Hironori Okada, Hidetoshi Ishibashi, Hiromi Hayashita-Kinoh, Tomoko Chiyo, Yuko Nitahara-Kasahara, Yukihiro Baba, Sumiko Watanabe, Shin'ichi Takeda, Takashi Okada
Published 2013-01-01

Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR)

by Ahmed Elhussieny, Ken’ichiro Nogami, Fusako Sakai-Takemura, Yusuke Maruyama, Natsumi Takemura, Wael Talaat Soliman, Shin’ichi Takeda, Yuko Miyagoe-Suzuki
Published 2021-10-01

Tubulointerstitial Nephritis and Uveitis Syndrome: Are Drugs Offenders or Bystanders?

by Mutsumi Kawamata, Tetsu Akimoto, Taro Sugase, Naoko Otani-Takei, Takuya Miki, Takahiro Masuda, Takahisa Kobayashi, Shin-ichi Takeda, Shigeaki Muto, Daisuke Nagata
Published 2016-03-01

Tubulointerstitial Nephritis and Uveitis Syndrome: Are Drugs Offenders or Bystanders?

by Mutsumi Kawamata, Tetsu Akimoto, Taro Sugase, Naoko Otani-Takei, Takuya Miki, Takahiro Masuda, Takahisa Kobayashi, Shin-Ichi Takeda, Shigeaki Muto, Daisuke Nagata
Published 2016-09-01

Scavenger Receptor Class A1 Mediates Uptake of Morpholino Antisense Oligonucleotide into Dystrophic Skeletal Muscle

by Shouta Miyatake, Yoshitaka Mizobe, Maria K. Tsoumpra, Kenji Rowel Q. Lim, Yuko Hara, Fazel Shabanpoor, Toshifumi Yokota, Shin’ichi Takeda, Yoshitsugu Aoki
Published 2019-03-01

Dental pulp stem cells can improve muscle dysfunction in animal models of Duchenne muscular dystrophy

by Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Posadas Herrera Guillermo, Hiromi Hayashita-Kinoh, Yasunobu Maruoka, Aki Nakamura-Takahasi, Koichi Kimura, Shin’ichi Takeda, Takashi Okada
Published 2021-01-01

Therapeutic Challenges to End-Stage Kidney Disease in a Patient with Tetralogy of Fallot

by Ken Ohara, Tetsu Akimoto, Takuya Miki, Naoko Otani, Taro Sugase, Takahiro Masuda, Takuya Murakami, Toshimi Imai, Shin-ichi Takeda, Yasuhiro Ando, Shigeaki Muto, Daisuke Nagata
Published 2015-01-01

Therapeutic Challenges to End-Stage Kidney Disease in a Patient with Tetralogy of Fallot

by Ken Ohara, Tetsu Akimoto, Takuya Miki, Naoko Otani, Taro Sugase, Takahiro Masuda, Takuya Murakami, Toshimi Imai, Shin-ichi Takeda, Yasuhiro Ando, Shigeaki Muto, Daisuke Nagata
Published 2015-11-01

Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status

by Yuko Miyagoe-Suzuki, Takashi Nishiyama, Miho Nakamura, Asako Narita, Fusako Takemura, Satoru Masuda, Narihiro Minami, Kumiko Murayama, Hirofumi Komaki, Yu-ichi Goto, Shin’ichi Takeda
Published 2017-01-01

Performing Anticoagulation: A Puzzling Case of Cholesterol Embolization Syndrome

by Yusuke Igarashi, Tetsu Akimoto, Takahisa Kobayashi, Yoshitaka Iwazu, Takuya Miki, Naoko Otani-Takei, Toshimi Imai, Taro Sugase, Takahiro Masuda, Shin-ichi Takeda, Shigeaki Muto, Daisuke Nagata
Published 2017-01-01

Peritoneal Dialysis and Retroperitoneal Laparoscopic Radical Nephrectomy: A Favorable Experience With a Patient Complicated by Renal Cell Carcinoma

by Reika Imai, Tetsu Akimoto, Takaaki Kimura, Marina Kohara, Toshihiro Shimizu, Kentaro Oka, Miwa Shuto, Maki Asakura, Izumi Nagayama, Shin-ichi Takeda, Takashi Yagisawa, Shigeaki Muto, Daisuke Nagata
Published 2017-12-01

Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche

by Masahiko Yamaguchi, Yoko Watanabe, Takuji Ohtani, Akiyoshi Uezumi, Norihisa Mikami, Miki Nakamura, Takahiko Sato, Masahito Ikawa, Mikio Hoshino, Kunihiro Tsuchida, Yuko Miyagoe-Suzuki, Kazutake Tsujikawa, Shin’ichi Takeda, Hiroshi Yamamoto, So-ichiro Fukada
Published 2015-10-01

Early phase 2 trial of TAS‐205 in patients with Duchenne muscular dystrophy

by Hirofumi Komaki, Yoshihiro Maegaki, Tsuyoshi Matsumura, Kazuhiro Shiraishi, Hiroyuki Awano, Akinori Nakamura, Satoru Kinoshita, Katsuhisa Ogata, Keiko Ishigaki, Shinji Saitoh, Michinori Funato, Satoshi Kuru, Takahiro Nakayama, Yasuyuki Iwata, Hiroyuki Yajima, Shin’ichi Takeda
Published 2020-02-01

The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

by Yasunari Matsuzaka, Jun Tanihata, Yoshiko Ooshima, Daisuke Yamada, Masayuki Sekiguchi, Shouta Miyatake, Yoshitsugu Aoki, Mika Terumitsu, Ryu Yashiro, Hirofumi Komaki, Akihiko Ishiyama, Yasushi Oya, Yukiko U. Inoue, Takayoshi Inoue, Shin’ichi Takeda, Kazuo Hashido
Published 2020-11-01