Mammalian Models of Duchenne Muscular Dystrophy: Pathological Characteristics and Therapeutic Applications

by Akinori Nakamura, Shin'ichi Takeda
Published 2011-01-01

Role of Ca2+ signaling in skeletal muscle hypertrophy and atrophy

by Naoki Ito, Shin’ichi Takeda
Published 2015-05-01

Changes in cytosolic Ca2+ dynamics in the sarcoplasmic reticulum associated with the pathology of Duchenne muscular dystrophy

by Jun Tanihata, Shin’ichi Takeda
Published 2016-10-01

ATP-Induced Increase in Intracellular Calcium Levels and Subsequent Activation of mTOR as Regulators of Skeletal Muscle Hypertrophy

by Naoki Ito, Urs T. Ruegg, Shin’ichi Takeda
Published 2018-09-01

Nonmechanical Roles of Dystrophin and Associated Proteins in Exercise, Neuromuscular Junctions, and Brains

by Bailey Nichols, Shin'ichi Takeda, Toshifumi Yokota
Published 2015-07-01

Periostin Is Required for the Maintenance of Muscle Fibers during Muscle Regeneration

by Naoki Ito, Yuko Miyagoe-Suzuki, Shin’ichi Takeda, Akira Kudo
Published 2021-03-01

Direct reprogramming of fibroblasts into skeletal muscle progenitor cells by transcription factors enriched in undifferentiated subpopulation of satellite cells

by Naoki Ito, Isao Kii, Noriaki Shimizu, Hirotoshi Tanaka, Shin’ichi Takeda
Published 2017-08-01

Hypoglycemic Coma in a Hemodialysis Patient Receiving Blood Glucose-Lowering Therapy With the Single Agent Teneligliptin

by Takumi Minezumi, Shin-ichi Takeda, Yusuke Igarashi, Kentaro Sato, Yoshiaki Murakami, Daisuke Nagata
Published 2018-03-01

Loss of RNA-Binding Protein Sfpq Causes Long-Gene Transcriptopathy in Skeletal Muscle and Severe Muscle Mass Reduction with Metabolic Myopathy

by Motoyasu Hosokawa, Akihide Takeuchi, Jun Tanihata, Kei Iida, Shin'ichi Takeda, Masatoshi Hagiwara
Published 2019-03-01

Treatment with the anti-IL-6 receptor antibody attenuates muscular dystrophy via promoting skeletal muscle regeneration in dystrophin-/utrophin-deficient mice

by Eiji Wada, Jun Tanihata, Akira Iwamura, Shin’ichi Takeda, Yukiko K. Hayashi, Ryoichi Matsuda
Published 2017-10-01

Restoring Dystrophin Expression in Duchenne Muscular Dystrophy: Current Status of Therapeutic Approaches

by Yuko Shimizu-Motohashi, Hirofumi Komaki, Norio Motohashi, Shin’ichi Takeda, Toshifumi Yokota, Yoshitsugu Aoki
Published 2019-01-01

Enhanced cell survival and therapeutic benefits of IL-10-expressing multipotent mesenchymal stromal cells for muscular dystrophy

by Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Yuki Oda, Hiromi Hayashita-Kinoh, Shin’ichi Takeda, Takashi Okada
Published 2021-02-01

Antisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patient.

by Takashi Saito, Akinori Nakamura, Yoshitsugu Aoki, Toshifumi Yokota, Takashi Okada, Makiko Osawa, Shin'ichi Takeda
Published 2010-01-01

Antisense PMO cocktails effectively skip dystrophin exons 45-55 in myotubes transdifferentiated from DMD patient fibroblasts.

by Joshua Lee, Yusuke Echigoya, William Duddy, Takashi Saito, Yoshitsugu Aoki, Shin'ichi Takeda, Toshifumi Yokota
Published 2018-01-01

Peptide-conjugate antisense based splice-correction for Duchenne muscular dystrophy and other neuromuscular diseases

by Maria K. Tsoumpra, Seiji Fukumoto, Toshio Matsumoto, Shin'ichi Takeda, Matthew J.A. Wood, Yoshitsugu Aoki
Published 2019-07-01

rAAV8 and rAAV9-Mediated Long-Term Muscle Transduction with Tacrolimus (FK506) in Non-Human Primates

by Akiko Ishii, Hironori Okada, Hiromi Hayashita-Kinoh, Jin-Hong Shin, Akira Tamaoka, Takashi Okada, Shin’ichi Takeda
Published 2020-09-01

Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice.

by Yasunari Matsuzaka, Jun Tanihata, Hirofumi Komaki, Akihiko Ishiyama, Yasushi Oya, Urs Rüegg, Shin-Ichi Takeda, Kazuo Hashido
Published 2016-01-01

Antineutrophil Cytoplasmic Antibody–associated Glomerulonephritis Complicated by Pneumatosis Intestinalis

by Saki Nakagawa, Tetsu Akimoto, Shin-ichi Takeda, Mari Okada, Atsushi Miki, Hisashi Yamamoto, Shigeaki Muto, Eiji Kusano, Daisuke Nagata
Published 2015-08-01

Antineutrophil Cytoplasmic Antibody–associated Glomerulonephritis Complicated by Pneumatosis Intestinalis

by Saki Nakagawa, Tetsu Akimoto, Shin-ichi Takeda, Mari Okada, Atsushi Miki, Hisashi Yamamoto, Shigeaki Muto, Eiji Kusano, Daisuke Nagata
Published 2015-01-01

Identification of muscle-specific microRNAs in serum of muscular dystrophy animal models: promising novel blood-based markers for muscular dystrophy.

by Hideya Mizuno, Akinori Nakamura, Yoshitsugu Aoki, Naoki Ito, Soichiro Kishi, Kazuhiro Yamamoto, Masayuki Sekiguchi, Shin'ichi Takeda, Kazuo Hashido
Published 2011-01-01