The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes

by Jakob Appel Østergaard, Fanny Jansson Sigfrids, Carol Forsblom, Emma H. Dahlström, Lena M. Thorn, Valma Harjutsalo, Allan Flyvbjerg, Steffen Thiel, Troels Krarup Hansen, Per-Henrik Groop
Published 2021-04-01

A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Termin...

by Laure Yatime, Nicolas S. Merle, Annette G. Hansen, Niels Anton Friis, Niels Anton Friis, Jakob A. Østergaard, Mette Bjerre, Lubka T. Roumenina, Steffen Thiel, Peter Kristensen, Gregers R. Andersen
Published 2018-11-01

Ficolin-1 and Ficolin-3 Plasma Levels Are Altered in HIV and HIV/HCV Coinfected Patients From Southern Brazil

by Maria Regina Tizzot, Kárita Cláudia Freitas Lidani, Fabiana Antunes Andrade, Hellen Weinschutz Mendes, Marcia Holsbach Beltrame, Edna Reiche, Steffen Thiel, Jens C. Jensenius, Iara J. de Messias-Reason
Published 2018-10-01

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5...

by Nicholas R. Medjeral-Thomas, Anne Troldborg, Nicholas Constantinou, Hannah J. Lomax-Browne, Annette G. Hansen, Michelle Willicombe, Charles D. Pusey, H. Terence Cook, Steffen Thiel, Matthew C. Pickering
Published 2018-03-01

Low levels of mannan-binding lectin or ficolins are not associated with an increased risk of cytomegalovirus disease in HIV-infected patients.

by Adrian Egli, Juliane Schäfer, Michael Osthoff, Steffen Thiel, Christina Mikkelsen, Andri Rauch, Hans H Hirsch, Heiner C Bucher, James Young, Jens C Jensenius, Manuel Battegay, Marten Trendelenburg, Swiss HIV Cohort Study
Published 2013-01-01

Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D

by V. Michael Holers, Anna Borodovsky, Robert I. Scheinman, Nhu Ho, Joseline Ramos Ramirez, József Dobó, Péter Gál, Jared Lindenberger, Annette G. Hansen, Dhruv Desai, Rasmus Pihl, Steffen Thiel, Nirmal K. Banda
Published 2020-02-01

Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-Level in Plasma Samples From Mice and Humans

by Lene Halkjær, Lene Halkjær, Lene Halkjær, Anne Troldborg, Anne Troldborg, Anne Troldborg, Henrik Pedersen, Lisbeth Jensen, Annette Gudmann Hansen, Troels Krarup Hansen, Mette Bjerre, Jakob Appel Østergaard, Jakob Appel Østergaard, Steffen Thiel
Published 2020-05-01

Complement lectin pathway protein levels reflect disease activity in juvenile idiopathic arthritis: a longitudinal study of the Nordic JIA cohort

by Mia Glerup, Steffen Thiel, Veronika Rypdal, Ellen Dalen Arnstad, Maria Ekelund, Suvi Peltoniemi, Kristiina Aalto, Marite Rygg, Susan Nielsen, Anders Fasth, Lillemor Berntson, Ellen Nordal, Troels Herlin, for the Nordic Study Group of Pediatric Rheumatology (NoSPeR)
Published 2019-09-01

Associations of ficolins and mannose-binding lectin with acute myeloid leukaemia in adults

by Anna Sokołowska, Anna S. Świerzko, Gabriela Gajek, Aleksandra Gołos, Mateusz Michalski, Mateusz Nowicki, Agnieszka Szala-Poździej, Anna Wolska-Washer, Olga Brzezińska, Agnieszka Wierzbowska, Krzysztof Jamroziak, Marek L. Kowalski, Steffen Thiel, Misao Matsushita, Jens C. Jensenius, Maciej Cedzyński
Published 2020-06-01

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

by Dennis V. Pedersen, Trine A. F. Gadeberg, Caroline Thomas, Yong Wang, Nicolas Joram, Rasmus K. Jensen, Sofia M. M. Mazarakis, Margot Revel, Carine El Sissy, Steen V. Petersen, Kresten Lindorff-Larsen, Steffen Thiel, Nick S. Laursen, Véronique Fremeaux-Bacchi, Gregers R. Andersen
Published 2019-08-01

The Role of Complement Activating Collectins and Associated Serine Proteases in Patients With Hematological Malignancies, Receiving High-Dose Chemotherapy, and Autologous Hematopoi...

by Anna S. Świerzko, Mateusz Michalski, Anna Sokołowska, Mateusz Nowicki, Łukasz Eppa, Agnieszka Szala-Poździej, Iwona Mitrus, Anna Szmigielska-Kapłon, Małgorzata Sobczyk-Kruszelnicka, Katarzyna Michalak, Aleksandra Gołos, Agnieszka Wierzbowska, Sebastian Giebel, Krzysztof Jamroziak, Marek L. Kowalski, Olga Brzezińska, Olga Brzezińska, Steffen Thiel, Jens C. Jensenius, Katarzyna Kasperkiewicz, Maciej Cedzyński
Published 2018-09-01

Associations of Ficolins With Hematological Malignancies in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantations

by Anna S. Świerzko, Mateusz Michalski, Anna Sokołowska, Mateusz Nowicki, Agnieszka Szala-Poździej, Łukasz Eppa, Iwona Mitrus, Anna Szmigielska-Kapłon, Małgorzata Sobczyk-Kruszelnicka, Katarzyna Michalak, Aleksandra Gołos, Agnieszka Wierzbowska, Sebastian Giebel, Krzysztof Jamroziak, Marek L. Kowalski, Olga Brzezińska, Olga Brzezińska, Steffen Thiel, Misao Matsushita, Jens C. Jensenius, Gabriela Gajek, Maciej Cedzyński
Published 2020-01-01

Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors

by Angelica Beate Winter Boldt, Angelica Beate Winter Boldt, Camila de Freitas Oliveira-Toré, Gabriela Canalli Kretzschmar, Hellen Weinschutz Mendes, Sérvio Túlio Stinghen, Fabiana Antunes Andrade, Valéria Bumiller-Bini, Letícia Boslooper Gonçalves, Anna Carolina de Moraes Braga, Ewalda von Rosen Seeling Stahlke, Thirumalaisamy P. Velavan, Thirumalaisamy P. Velavan, Thirumalaisamy P. Velavan, Steffen Thiel, Iara José Taborda de Messias-Reason
Published 2021-02-01

Plasma Lectin Pathway Complement Proteins in Patients With COVID-19 and Renal Disease

by Nicholas R. Medjeral-Thomas, Nicholas R. Medjeral-Thomas, Anne Troldborg, Anne Troldborg, Annette G. Hansen, Jack Gisby, Candice L. Clarke, Candice L. Clarke, Maria Prendecki, Maria Prendecki, Stephen P. McAdoo, Stephen P. McAdoo, Eleanor Sandhu, Eleanor Sandhu, Liz Lightstone, Liz Lightstone, David C. Thomas, David C. Thomas, Michelle Willicombe, Michelle Willicombe, Marina Botto, James E. Peters, Matthew C. Pickering, Steffen Thiel
Published 2021-04-01

A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Per...

by Vibeke Andersen, Uffe Holmskov, Signe Bek Sørensen, Mohamad Jawhara, Karina W. Andersen, Anette Bygum, Lone Hvid, Jakob Grauslund, Jimmi Wied, Henning Glerup, Ulrich Fredberg, Jan Alexander Villadsen, Søren Geill Kjær, Jan Fallingborg, Seyed A. G. R. Moghadd, Torben Knudsen, Jacob Brodersen, Jesper Frøjk, Jens F. Dahlerup, Ole Haagen Nielsen, Robin Christensen, Anders Bo Bojesen, Grith Lykke Sorensen, Steffen Thiel, Nils J. Færgeman, Ivan Brandslund, Allan Stensballe, Erik Berg Schmidt, Andre Franke, David Ellinghaus, Philip Rosenstiel, Jeroen Raes, Berit Heitmann, Mette Boye, Charlotte Lindgaard Nielsen, Lars Werner, Jens Kjeldsen, Torkell Ellingsen
Published 2017-05-01