Association between delay in intensive care unit admission and the host response in patients with community-acquired pneumonia

by Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Olaf L. Cremer, Marcus J. Schultz, Marc M. J. Bonten, Brendon P. Scicluna, Tom van der Poll, the MARS consortium
Published 2021-09-01

Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis

by Natasja A. Otto, Liza Pereverzeva, Valentine Leopold, Ivan Ramirez-Moral, Joris J. T. H. Roelofs, Jeroen W. J. van Heijst, Alex F. de Vos, Tom van der Poll
Published 2021-01-01

Robustness of sepsis-3 criteria in critically ill patients

by Diana M. Verboom, Jos F. Frencken, David S. Y. Ong, Janneke Horn, Tom van der Poll, Marc J. M. Bonten, Olaf L. Cremer, Peter M. C. Klein Klouwenberg
Published 2019-08-01

The neutrophil-lymphocyte count ratio in patients with community-acquired pneumonia.

by Cornelis P C de Jager, Peter C Wever, Eugenie F A Gemen, Ron Kusters, Arianne B van Gageldonk-Lafeber, Tom van der Poll, Robert J F Laheij
Published 2012-01-01

Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization.

by Joppe W R Hovius, Marein A W P de Jong, Jeroen den Dunnen, Manja Litjens, Erol Fikrig, Tom van der Poll, Sonja I Gringhuis, Teunis B H Geijtenbeek
Published 2008-02-01

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia.

by Ahmed Achouiti, Alex F de Vos, Cornelis van 't Veer, Sandrine Florquin, Michael W Tanck, Peter P Nawroth, Angelika Bierhaus, Tom van der Poll, Marieke A D van Zoelen
Published 2016-01-01

Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis.

by Jiri F P Wagenaar, M Hussein Gasem, Marga G A Goris, Mariska Leeflang, Rudy A Hartskeerl, Tom van der Poll, Cornelis van 't Veer, Eric C M van Gorp
Published 2009-06-01

Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei (melioidosis).

by Gerritje J W van der Windt, W Joost Wiersinga, Catharina W Wieland, Ivo C S I Tjia, Nicholas P Day, Sharon J Peacock, Sandrine Florquin, Tom van der Poll
Published 2010-08-01

Alkaline phosphatase in pulmonary inflammation—a translational study in ventilated critically ill patients and rats

by Jenny Juschten, Sarah A. Ingelse, Lieuwe D. J. Bos, Armand R. J. Girbes, Nicole P. Juffermans, Tom van der Poll, Marcus J. Schultz, Pieter Roel Tuinman, for the BASIC study investigators
Published 2020-12-01

Nebulized fibrinolytic agents improve pulmonary fibrinolysis but not inflammation in rat models of direct and indirect acute lung injury.

by Jorrit J Hofstra, Alexander D Cornet, Paul J Declerck, Barry Dixon, Hamid Aslami, Alexander P J Vlaar, Joris J Roelofs, Tom van der Poll, Marcel Levi, Marcus J Schultz
Published 2013-01-01

S100A8/A9 is not involved in host defense against murine urinary tract infection.

by Mark C Dessing, Loes M Butter, Gwendoline J Teske, Nike Claessen, Chris M van der Loos, Thomas Vogl, Johannes Roth, Tom van der Poll, Sandrine Florquin, Jaklien C Leemans
Published 2010-01-01

A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense.

by Henrike Veninga, Robert M Hoek, Alex F de Vos, Alex M de Bruin, Feng-Qi An, Tom van der Poll, René A W van Lier, M Edward Medof, Jörg Hamann
Published 2011-01-01

Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS

by Luis Morales-Quinteros, Marcus J. Schultz, Josep Bringué, Carolyn S. Calfee, Marta Camprubí, Olaf L. Cremer, Janneke Horn, Tom van der Poll, Pratik Sinha, Antonio Artigas, Lieuwe D. Bos, MARS Consortium
Published 2019-11-01

Borrelia burgdorferi Induces TLR2-Mediated Migration of Activated Dendritic Cells in an Ex Vivo Human Skin Model.

by Lauren M K Mason, Alex Wagemakers, Cornelis van 't Veer, Anneke Oei, Wouter J van der Pot, Kalam Ahmed, Tom van der Poll, Teunis B H Geijtenbeek, Joppe W R Hovius
Published 2016-01-01

Investigational treatment of rheumatoid arthritis with a vibrotactile device applied to the external ear

by Meghan E. Addorisio, Gavin H. Imperato, Alex F. de Vos, Steve Forti, Richard S. Goldstein, Valentin A. Pavlov, Tom van der Poll, Huan Yang, Betty Diamond, Kevin J. Tracey, Sangeeta S. Chavan
Published 2019-04-01

Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice

by Desirée Perlee, Alex F. de Vos, Brendon P. Scicluna, Anja Maag, Pablo Mancheño, Olga de la Rosa, Wilfried Dalemans, Sandrine Florquin, Cornelis van’t Veer, Eleuterio Lombardo, Tom van der Poll
Published 2019-09-01

Expression of intra- and extracellular granzymes in patients with typhoid fever.

by Hanna K de Jong, Maria Isabel Garcia-Laorden, Arie J Hoogendijk, Christopher M Parry, Rapeephan R Maude, Arjen M Dondorp, Mohammed Abul Faiz, Tom van der Poll, Willem Joost Wiersinga
Published 2017-07-01

Correction: Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis.

by Emma Birnie, Gavin C K W Koh, Ester C Löwenberg, Joost C M Meijers, Rapeephan R Maude, Nicholas P J Day, Sharon J Peacock, Tom van der Poll, W Joost Wiersinga
Published 2020-09-01

The Enterococcus faecium enterococcal biofilm regulator, EbrB, regulates the esp operon and is implicated in biofilm formation and intestinal colonization.

by Janetta Top, Fernanda L Paganelli, Xinglin Zhang, Willem van Schaik, Helen L Leavis, Miranda van Luit-Asbroek, Tom van der Poll, Masja Leendertse, Marc J M Bonten, Rob J L Willems
Published 2013-01-01

Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Impairs Host Defense in Experimental Melioidosis.

by Tassili A F Weehuizen, Tijmen J Hommes, Jacqueline M Lankelma, Hanna K de Jong, Joris J T H Roelofs, Alex F de Vos, Marco Colonna, Tom van der Poll, W Joost Wiersinga
Published 2016-06-01