Post-treatment with the PPAR-γ agonist pioglitazone inhibits inflammation and bacterial growth during Klebsiella pneumonia

by Ivan Ramirez-Moral, Bianca Lima Ferreira, Alex F. de Vos, Tom van der Poll
Published 2021-08-01

Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice.

by Mark C Dessing, Robert A Hirst, Alex F de Vos, Tom van der Poll
Published 2009-11-01

CEBPD Potentiates the Macrophage Inflammatory Response but CEBPD Knock-Out Macrophages Fail to Identify CEBPD-Dependent Pro-Inflammatory Transcriptional Programs

by C. Arnold Spek, Hella L. Aberson, Joe M. Butler, Alex F. de Vos, JanWillem Duitman
Published 2021-08-01

Early specific host response associated with starting effective tuberculosis treatment in an infection controlled placebo controlled mouse study.

by Alice L den Hertog, Alex F de Vos, Paul R Klatser, Paul R Klatser, Richard M Anthony
Published 2013-01-01

Role of CD14 in a mouse model of acute lung inflammation induced by different lipopolysaccharide chemotypes.

by Adam A Anas, Joppe W R Hovius, Cornelis van 't Veer, Tom van der Poll, Alex F de Vos
Published 2010-01-01

Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae-Evoked Pneumosepsis in Mice

by Mariska T. Meijer, Mariska T. Meijer, Alex F. de Vos, Alex F. de Vos, Brendon P. Scicluna, Brendon P. Scicluna, Brendon P. Scicluna, Joris J. Roelofs, Chérine Abou Fayçal, Gertraud Orend, Fabrice Uhel, Fabrice Uhel, Tom van der Poll, Tom van der Poll, Tom van der Poll
Published 2021-03-01

Effect of antibiotic gut microbiota disruption on LPS-induced acute lung inflammation.

by Max C Jacobs, Jacqueline M Lankelma, Nora S Wolff, Floor Hugenholtz, Alex F de Vos, Tom van der Poll, W Joost Wiersinga
Published 2020-01-01

Vendor effects on murine gut microbiota and its influence on lipopolysaccharide-induced lung inflammation and Gram-negative pneumonia

by Nora S. Wolff, Max C. Jacobs, Bastiaan W. Haak, Joris J. T. H. Roelofs, Alex F. de Vos, Floor Hugenholtz, W. Joost Wiersinga
Published 2020-08-01

Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis.

by Miriam H P van Lieshout, Adam A Anas, Sandrine Florquin, Baidong Hou, Cornelis van't Veer, Alex F de Vos, Tom van der Poll
Published 2014-09-01

Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis

by M. Isabel García-Laorden, Ingrid Stroo, Sanne Terpstra, Sandrine Florquin, Jan Paul Medema, Cornelis van´t Veer, Alex F. de Vos, Tom van der Poll
Published 2017-01-01

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection.

by Wanhai Qin, Xanthe Brands, Cornelis Van't Veer, Alex F de Vos, Jean-Claude Sirard, Joris J T H Roelofs, Brendon P Scicluna, Tom van der Poll
Published 2021-04-01

Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae

by Desiree Perlee, Alex F. deVos, Brendon P. Scicluna, Pablo Mancheño, Olga de laRosa, Wilfried Dalemans, Peter Nürnberg, Eleuterio Lombardo, Tom van derPoll
Published 2019-08-01

Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia.

by Dana C Blok, Koenraad F van der Sluijs, Sandrine Florquin, Onno J de Boer, Cornelis van 't Veer, Alex F de Vos, Tom van der Poll
Published 2013-01-01

Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model

by Jack Yang, Ivan Ramirez Moral, Cornelis van ’t Veer, Alex F. de Vos, Regina de Beer, Joris J. T. H. Roelofs, B. Paul Morgan, Tom van der Poll
Published 2019-07-01

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia

by Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos
Published 2019-01-01

Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia.

by Tijmen J Hommes, Miriam H van Lieshout, Cornelis van 't Veer, Sandrine Florquin, Hester J Bootsma, Peter W Hermans, Alex F de Vos, Tom van der Poll
Published 2015-01-01

Bruton’s Tyrosine Kinase-Mediated Signaling in Myeloid Cells Is Required for Protective Innate Immunity During Pneumococcal Pneumonia

by Alexander P. de Porto, Zhe Liu, Zhe Liu, Regina de Beer, Regina de Beer, Sandrine Florquin, Joris J. T. H. Roelofs, Onno J. de Boer, Joke M. M. den Haan, Rudi W. Hendriks, Cornelis van ‘t Veer, Cornelis van ‘t Veer, Tom van der Poll, Tom van der Poll, Tom van der Poll, Alex F. de Vos, Alex F. de Vos
Published 2021-09-01

Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis

by Natasja A. Otto, Liza Pereverzeva, Valentine Leopold, Ivan Ramirez-Moral, Joris J. T. H. Roelofs, Jeroen W. J. van Heijst, Alex F. de Vos, Tom van der Poll
Published 2021-01-01

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia.

by Ahmed Achouiti, Alex F de Vos, Cornelis van 't Veer, Sandrine Florquin, Michael W Tanck, Peter P Nawroth, Angelika Bierhaus, Tom van der Poll, Marieke A D van Zoelen
Published 2016-01-01

A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense.

by Henrike Veninga, Robert M Hoek, Alex F de Vos, Alex M de Bruin, Feng-Qi An, Tom van der Poll, René A W van Lier, M Edward Medof, Jörg Hamann
Published 2011-01-01