Monoclonal Antibodies Capable of Inhibiting Complement Downstream of C5 in Multiple Species

by Wioleta M. Zelek, B. Paul Morgan
Published 2020-12-01

Professor Sir Peter J. Lachmann, FRS, FMedSci (1931–2020)

by Richard A. Harrison, B. Paul Morgan
Published 2021-05-01

Exploiting the Nephrotoxic Effects of Venom from the Sea Anemone, <em>Phyllodiscus semoni</em>, to Create a Hemolytic Uremic Syndrome Model in the Rat

by B. Paul Morgan, Masashi Mizuno, Yasuhiko Ito
Published 2012-07-01

An “Outside-In” and “Inside-Out” Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases

by B. Paul Morgan, Jennifer L. Gommerman, Valeria Ramaglia
Published 2021-01-01

Structural basis of complement membrane attack complex formation

by Marina Serna, Joanna L. Giles, B. Paul Morgan, Doryen Bubeck
Published 2016-02-01

Effects of freezer storage time on levels of complement biomarkers

by Angharad R. Morgan, Caroline O’Hagan, Samuel Touchard, Simon Lovestone, B. Paul Morgan
Published 2017-11-01

Affinity purification of human factor H on polypeptides derived from streptococcal m protein: enrichment of the Y402 variant.

by O Rickard Nilsson, Jonas Lannergård, B Paul Morgan, Gunnar Lindahl, Mattias C U Gustafsson
Published 2013-01-01

Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer’s disease

by Ryan J. Bevan, Tim R. Hughes, Pete A. Williams, Mark A. Good, B. Paul Morgan, James E. Morgan
Published 2020-12-01

Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients: An observational cohort study.

by Isa Murrell, Donall Forde, Wioleta Zelek, Linda Tyson, Lisa Chichester, Nicki Palmer, Rachel Jones, B Paul Morgan, Catherine Moore
Published 2021-01-01

A novel mouse model expressing human forms for complement receptors CR1 and CR2

by Harriet M. Jackson, Kate E. Foley, Rita O’Rourke, Timothy M. Stearns, Dina Fathalla, B. Paul Morgan, Gareth R. Howell
Published 2020-09-01

The Impact of Complement Genes on the Risk of Late-Onset Alzheimer’s Disease

by Sarah M. Carpanini, Janet C. Harwood, Emily Baker, Megan Torvell, The GERAD1 Consortium, Rebecca Sims, Julie Williams, B. Paul Morgan
Published 2021-03-01

CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers

by Anaïs Menny, Marina Serna, Courtney M. Boyd, Scott Gardner, Agnel Praveen Joseph, B. Paul Morgan, Maya Topf, Nicholas J. Brooks, Doryen Bubeck
Published 2018-12-01

High Levels of Soluble C5b-9 Complex in Dialysis Fluid May Predict Poor Prognosis in Peritonitis in Peritoneal Dialysis Patients.

by Masashi Mizuno, Yasuhiro Suzuki, Keiko Higashide, Yumi Sei, Daiki Iguchi, Fumiko Sakata, Masanobu Horie, Shoichi Maruyama, Seiichi Matsuo, B Paul Morgan, Yasuhiko Ito
Published 2017-01-01

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9

by Michael A. Hadders, Doryen Bubeck, Pietro Roversi, Svetlana Hakobyan, Federico Forneris, B. Paul Morgan, Michael K. Pangburn, Oscar Llorca, Susan M. Lea, Piet Gros
Published 2012-03-01

Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection.

by Matheswaran Kandasamy, Poon C Ying, Adrian W S Ho, Hermi R Sumatoh, Andreas Schlitzer, Timothy R Hughes, David M Kemeny, B Paul Morgan, Florent Ginhoux, Baalasubramanian Sivasankar
Published 2013-01-01

Complement factor C5 inhibition reduces type 2 responses without affecting group 2 innate lymphoid cells in a house dust mite induced murine asthma model

by Jack Yang, Ivan Ramirez Moral, Cornelis van ’t Veer, Alex F. de Vos, Regina de Beer, Joris J. T. H. Roelofs, B. Paul Morgan, Tom van der Poll
Published 2019-07-01

Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in...

by Jian Liu, David A Copland, Shintaro Horie, Wei-Kang Wu, Mei Chen, Yunhe Xu, B Paul Morgan, Matthias Mack, Heping Xu, Lindsay B Nicholson, Andrew D Dick
Published 2013-01-01

Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice

by Sidonia Mihai, Sidonia Mihai, Misa Hirose, Yi Wang, Joshua M. Thurman, V. Michael Holers, B. Paul Morgan, Jörg Köhl, Jörg Köhl, Detlef Zillikens, Ralf J. Ludwig, Falk Nimmerjahn
Published 2018-03-01

Development of EndoScreen Chip, a Microfluidic Pre-Endoscopy Triage Test for Esophageal Adenocarcinoma

by Julie A. Webster, Alain Wuethrich, Karthik B. Shanmugasundaram, Renee S. Richards, Wioleta M. Zelek, Alok K. Shah, Louisa G. Gordon, Bradley J. Kendall, Gunter Hartel, B. Paul Morgan, Matt Trau, Michelle M. Hill
Published 2021-06-01

Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration

by Valentina Cipriani, Laura Lorés-Motta, Fan He, Dina Fathalla, Viranga Tilakaratna, Selina McHarg, Nadhim Bayatti, İlhan E. Acar, Carel B. Hoyng, Sascha Fauser, Anthony T. Moore, John R. W. Yates, Eiko K. de Jong, B. Paul Morgan, Anneke I. den Hollander, Paul N. Bishop, Simon J. Clark
Published 2020-02-01