Potential Therapeutic Benefit of NAD⁺ Supplementation for Glaucoma and Age-Related Macular Degeneration

by Gloria Cimaglia, Marcela Votruba, James E. Morgan, Helder André, Pete A. Williams
Published 2020-09-01

Digestion of the glycosaminoglycan extracellular matrix by chondroitinase ABC supports retinal ganglion cell dendritic preservation in a rodent model of experimental glaucoma

by James R. Tribble, Pete A. Williams, Bruce Caterson, Frank Sengpiel, James E. Morgan
Published 2018-11-01

Crowdsourcing as a novel technique for retinal fundus photography classification: analysis of images in the EPIC Norfolk cohort on behalf of the UK Biobank Eye and Vision Consortiu...

by Danny Mitry, Tunde Peto, Shabina Hayat, James E Morgan, Kay-Tee Khaw, Paul J Foster
Published 2013-01-01

Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer’s disease

by Ryan J. Bevan, Tim R. Hughes, Pete A. Williams, Mark A. Good, B. Paul Morgan, James E. Morgan
Published 2020-12-01

Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma.

by Pete A Williams, Gareth R Howell, Jessica M Barbay, Catherine E Braine, Gregory L Sousa, Simon W M John, James E Morgan
Published 2013-01-01

Non-invasive detection of early retinal neuronal degeneration by ultrahigh resolution optical coherence tomography.

by Debbie Tudor, Vedran Kajić, Sara Rey, Irina Erchova, Boris Považay, Bernd Hofer, Kate A Powell, David Marshall, Paul L Rosin, Wolfgang Drexler, James E Morgan
Published 2014-01-01

Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

by James R. Tribble, Amin Otmani, Shanshan Sun, Sevannah A. Ellis, Gloria Cimaglia, Rupali Vohra, Melissa Jöe, Emma Lardner, Abinaya P. Venkataraman, Alberto Domínguez-Vicent, Eirini Kokkali, Seungsoo Rho, Gauti Jóhannesson, Robert W. Burgess, Peter G. Fuerst, Rune Brautaset, Miriam Kolko, James E. Morgan, Jonathan G. Crowston, Marcela Votruba, Pete A. Williams
Published 2021-07-01

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

by Puya Gharahkhani, Eric Jorgenson, Pirro Hysi, Anthony P. Khawaja, Sarah Pendergrass, Xikun Han, Jue Sheng Ong, Alex W. Hewitt, Ayellet V. Segrè, John M. Rouhana, Andrew R. Hamel, Robert P. Igo, Helene Choquet, Ayub Qassim, Navya S. Josyula, Jessica N. Cooke Bailey, Pieter W. M. Bonnemaijer, Adriana Iglesias, Owen M. Siggs, Terri L. Young, Veronique Vitart, Alberta A. H. J. Thiadens, Juha Karjalainen, Steffen Uebe, Ronald B. Melles, K. Saidas Nair, Robert Luben, Mark Simcoe, Nishani Amersinghe, Angela J. Cree, Rene Hohn, Alicia Poplawski, Li Jia Chen, Shi-Song Rong, Tin Aung, Eranga Nishanthie Vithana, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team, Gen Tamiya, Yukihiro Shiga, Masayuki Yamamoto, Toru Nakazawa, Hannah Currant, Ewan Birney, Xin Wang, Adam Auton, Michelle K. Lupton, Nicholas G. Martin, Adeyinka Ashaye, Olusola Olawoye, Susan E. Williams, Stephen Akafo, Michele Ramsay, Kazuki Hashimoto, Yoichiro Kamatani, Masato Akiyama, Yukihide Momozawa, Paul J. Foster, Peng T. Khaw, James E. Morgan, Nicholas G. Strouthidis, Peter Kraft, Jae H. Kang, Chi Pui Pang, Francesca Pasutto, Paul Mitchell, Andrew J. Lotery, Aarno Palotie, Cornelia van Duijn, Jonathan L. Haines, Chris Hammond, Louis R. Pasquale, Caroline C. W. Klaver, Michael Hauser, Chiea Chuen Khor, David A. Mackey, Michiaki Kubo, Ching-Yu Cheng, Jamie E. Craig, Stuart MacGregor, Janey L. Wiggs
Published 2021-02-01