Potent innate immune response to pathogenic leptospira in human whole blood.

by Marga G A Goris, Jiri F P Wagenaar, Rudy A Hartskeerl, Eric C M van Gorp, Simone Schuller, Avril M Monahan, Jarlath E Nally, Tom van der Poll, Cornelis van 't Veer
Published 2011-01-01

Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis.

by Emma Birnie, Gavin C K W Koh, Ester C Löwenberg, Joost C M Meijers, Rapeephan R Maude, Nicholas P J Day, Sharon J Peacock, Tom van der Poll, W Joost Wiersinga
Published 2017-03-01

Myeloid-related protein-14 contributes to protective immunity in gram-negative pneumonia derived sepsis.

by Ahmed Achouiti, Thomas Vogl, Constantin F Urban, Marc Röhm, Tijmen J Hommes, Marieke A D van Zoelen, Sandrine Florquin, Johannes Roth, Cornelis van 't Veer, Alex F de Vos, Tom van der Poll
Published 2012-01-01

Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.

by W Joost Wiersinga, Thierry Calandra, Liesbeth M Kager, Gerritje J W van der Windt, Thierry Roger, Didier le Roy, Sandrine Florquin, Sharon J Peacock, Fred C G J Sweep, Tom van der Poll
Published 2010-02-01

The host response in critically ill sepsis patients on statin therapy: a prospective observational study

by Maryse A. Wiewel, Brendon P. Scicluna, Lonneke A. van Vught, Arie J. Hoogendijk, Aeilko H. Zwinderman, René Lutter, Janneke Horn, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz, Tom van der Poll
Published 2018-01-01

Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice.

by Ingrid Stroo, Jack Yang, Adam A Anas, J Daan de Boer, Gerard van Mierlo, Dorina Roem, Diana Wouters, Ruchira Engel, Joris J T H Roelofs, Cornelis van 't Veer, Tom van der Poll, Sacha Zeerleder
Published 2017-01-01

The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients

by Friso M. de Beer, Luuk Wieske, Gerard van Mierlo, Diana Wouters, Sacha Zeerleder, Lieuwe D. Bos, Nicole P. Juffermans, Marcus J. Schultz, Tom van der Poll, Wim K. Lagrand, Janneke Horn, for the BASIC–study group
Published 2020-12-01

Aging and Microglial Response following Systemic Stimulation with <i>Escherichia coli</i> in Mice

by Inge C.M. Hoogland, Dunja Westhoff, Joo-Yeon Engelen-Lee, Mercedes Valls Seron, Judith H.M.P. Houben-Weerts, David J. van Westerloo, Tom van der Poll, Willem A. van Gool, Diederik van de Beek
Published 2021-01-01

The predictive validity for mortality of the driving pressure and the mechanical power of ventilation

by David M. P. van Meenen, Ary Serpa Neto, Frederique Paulus, Coen Merkies, Laura R. Schouten, Lieuwe D. Bos, Janneke Horn, Nicole P. Juffermans, Olaf L. Cremer, Tom van der Poll, Marcus J. Schultz, for the MARS Consortium
Published 2020-12-01

Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display.

by Tim J Schuijt, Sukanya Narasimhan, Sirlei Daffre, Kathleen DePonte, Joppe W R Hovius, Cornelis Van't Veer, Tom van der Poll, Kamran Bakhtiari, Joost C M Meijers, Eric T Boder, Alje P van Dam, Erol Fikrig
Published 2011-01-01

The gut microbiota as a modulator of innate immunity during melioidosis.

by Jacqueline M Lankelma, Emma Birnie, Tassili A F Weehuizen, Brendon P Scicluna, Clara Belzer, Riekelt H Houtkooper, Joris J T H Roelofs, Alex F de Vos, Tom van der Poll, Andries E Budding, W Joost Wiersinga
Published 2017-04-01

Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury.

by Maria T Kuipers, Hamid Aslami, Alexander P J Vlaar, Nicole P Juffermans, Anita M Tuip-de Boer, Maria A Hegeman, Geartsje Jongsma, Joris J T H Roelofs, Tom van der Poll, Marcus J Schultz, Catharina W Wieland
Published 2012-01-01

High levels of S100A8/A9 proteins aggravate ventilator-induced lung injury via TLR4 signaling.

by Maria T Kuipers, Thomas Vogl, Hamid Aslami, Geartsje Jongsma, Elske van den Berg, Alexander P J Vlaar, Joris J T H Roelofs, Nicole P Juffermans, Marcus J Schultz, Tom van der Poll, Johannes Roth, Catharina W Wieland
Published 2013-01-01

Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumonia

by Alex R Schuurman, Tom DY Reijnders, Anno Saris, Ivan Ramirez Moral, Michiel Schinkel, Justin de Brabander, Christine van Linge, Louis Vermeulen, Brendon P Scicluna, W Joost Wiersinga, Felipe A Vieira Braga, Tom van der Poll
Published 2021-08-01

An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration

by Xanthe Brands, Bastiaan W. Haak, Augustijn M. Klarenbeek, Joe Butler, Fabrice Uhel, Wanhai Qin, Natasja A. Otto, Marja E. Jakobs, Daniël R. Faber, René Lutter, W. Joost Wiersinga, Tom van der Poll, Brendon P. Scicluna
Published 2021-08-01

Glyburide reduces bacterial dissemination in a mouse model of melioidosis.

by Gavin C K W Koh, Tassili A Weehuizen, Katrin Breitbach, Kathrin Krause, Hanna K de Jong, Liesbeth M Kager, Arjan J Hoogendijk, Antje Bast, Sharon J Peacock, Tom van der Poll, Ivo Steinmetz, W Joost Wiersinga
Published 2013-01-01

The EHA Research Roadmap: Blood Coagulation and Hemostatic Disorders

by Sabine Eichinger, Pierre E. Morange, Marco Cattaneo, Mathilde Fretigny, Antoine Rauch, Astrid van Hylckama Vlieg, David-Alexandre Trégouët, Wolfram Ruf, Marcel Levi, José A. Páramo, Tom van der Poll, Paul A. Kyrle, Isabella Garagiola, Flora Peyvandi
Published 2021-10-01

Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort s...

by Kirsten van de Groep, Stefan Nierkens, Olaf L. Cremer, Linda M. Peelen, Peter M. C. Klein Klouwenberg, Marcus J. Schultz, C. Erik Hack, Tom van der Poll, Marc J. M. Bonten, David S. Y. Ong, on behalf of the MARS consortium
Published 2018-12-01

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).

by Liesbeth M Kager, Marcel Schouten, W Joost Wiersinga, J Daan de Boer, Lionel C W Lattenist, Joris J T H Roelofs, Joost C M Meijers, Marcel Levi, Arjen M Dondorp, Charles T Esmon, Cornelis van 't Veer, Tom van der Poll
Published 2013-01-01

The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis

by Hina N. Khan, Xanthe Brands, Simona Aufiero, Arie J. Hoogendijk, Augustijn M. Klarenbeek, Tjitske S. R. van Engelen, Bastiaan W. Haak, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Tom van der Poll, Brendon P. Scicluna
Published 2020-07-01