The Combination Vaccine Adjuvant System Alum/c-di-AMP Results in Quantitative and Qualitative Enhanced Immune Responses Post Immunization

by Thomas Ebensen, Simon Delandre, Blair Prochnow, Carlos A. Guzmán, Kai Schulze
Published 2019-02-01

Neutral Lipopolyplexes for In Vivo Delivery of Conventional and Replicative RNA Vaccine

by Federico Perche, Rudy Clemençon, Kai Schulze, Thomas Ebensen, Carlos A. Guzmán, Chantal Pichon
Published 2019-09-01

Invariant NKT Cell-Mediated Modulation of ILC1s as a Tool for Mucosal Immune Intervention

by Stephanie Trittel, Neha Vashist, Neha Vashist, Thomas Ebensen, Benedict J. Chambers, Carlos A. Guzmán, Peggy Riese
Published 2019-08-01

Immunization with Tc52 or its amino terminal domain adjuvanted with c-di-AMP induces Th17+Th1 specific immune responses and confers protection against Trypanosoma cruzi.

by Marina N Matos, Silvia I Cazorla, Kai Schulze, Thomas Ebensen, Carlos A Guzmán, Emilio L Malchiodi
Published 2017-02-01

Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression

by Neha Vashist, Neha Vashist, Stephanie Trittel, Thomas Ebensen, Benedict J. Chambers, Carlos A. Guzmán, Peggy Riese
Published 2018-03-01

Establishment, Validation, and Initial Application of a Sensitive LC-MS/MS Assay for Quantification of the Naturally Occurring Isomers Itaconate, Mesaconate, and Citraconate

by Moritz Winterhoff, Fangfang Chen, Nishika Sahini, Thomas Ebensen, Maike Kuhn, Volkhard Kaever, Heike Bähre, Frank Pessler
Published 2021-04-01

Cyclic Di-Adenosine Monophosphate: A Promising Adjuvant Candidate for the Development of Neonatal Vaccines

by Darío Lirussi, Sebastian Felix Weissmann, Thomas Ebensen, Ursula Nitsche-Gloy, Heiko B. G. Franz, Carlos A. Guzmán
Published 2021-02-01

Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway

by Darío Lirussi, Thomas Ebensen, Kai Schulze, Stephanie Trittel, Veronica Duran, Ines Liebich, Ulrich Kalinke, Carlos A. Guzmán
Published 2017-08-01

Intranasal delivery of influenza rNP adjuvanted with c-di-AMP induces strong humoral and cellular immune responses and provides protection against virus challenge.

by Maria Victoria Sanchez, Thomas Ebensen, Kai Schulze, Diego Cargnelutti, Paulina Blazejewska, Eduardo A Scodeller, Carlos A Guzmán
Published 2014-01-01

Evaluation of the sublingual route for administration of influenza H5N1 virosomes in combination with the bacterial second messenger c-di-GMP.

by Gabriel Kristian Pedersen, Thomas Ebensen, Ingrid Hjetland Gjeraker, Signe Svindland, Geir Bredholt, Carlos Alberto Guzmán, Rebecca Jane Cox
Published 2011-01-01

Prophylactic Multi-Subunit Vaccine against <i>Chlamydia trachomatis:</i> In Vivo Evaluation in Mice

by Christian Lanfermann, Sebastian Wintgens, Thomas Ebensen, Martin Kohn, Robert Laudeley, Kai Schulze, Claudia Rheinheimer, Johannes H. Hegemann, Carlos Alberto Guzmán, Andreas Klos
Published 2021-06-01

Immune Responses to Pandemic H1N1 Influenza Virus Infection in Pigs Vaccinated with a Conserved Hemagglutinin HA1 Peptide Adjuvanted with CAF^®01 or CDA/αGalCerMPEG

by Sergi López-Serrano, Lorena Cordoba, Mónica Pérez-Maillo, Patricia Pleguezuelos, Edmond J. Remarque, Thomas Ebensen, Carlos A. Guzmán, Dennis Christensen, Joaquim Segalés, Ayub Darji
Published 2021-07-01

Role of Autophagy in Von Willebrand Factor Secretion by Endothelial Cells and in the In Vivo Thrombin-Antithrombin Complex Formation Promoted by the HIV-1 Matrix Protein p17

by Antonella Bugatti, Stefania Marsico, Pietro Mazzuca, Kai Schulze, Thomas Ebensen, Cinzia Giagulli, Esther Peña, Lina Badimón, Mark Slevin, Arnaldo Caruso, Carlos A. Guzman, Francesca Caccuri
Published 2020-03-01

Self-Amplifying Replicon RNA Delivery to Dendritic Cells by Cationic Lipids

by Pavlos C. Englezou, Cedric Sapet, Thomas Démoulins, Panagiota Milona, Thomas Ebensen, Kai Schulze, Carlos-Alberto Guzman, Florent Poulhes, Olivier Zelphati, Nicolas Ruggli, Kenneth C. McCullough
Published 2018-09-01

Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge.

by Xiaoyan Zheng, Jennifer D Oduro, Julia D Boehme, Lisa Borkner, Thomas Ebensen, Ulrike Heise, Marcus Gereke, Marina C Pils, Astrid Krmpotic, Carlos A Guzmán, Dunja Bruder, Luka Čičin-Šain
Published 2019-09-01

Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection

by Andrés Sanchez Alberti, Augusto E. Bivona, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Celina Morales, Angel M. Padilla, Silvia I. Cazorla, Rick L. Tarleton, Carlos A. Guzmán, Emilio L. Malchiodi
Published 2017-04-01

Modeling Influenza Virus Infection: A Roadmap for Influenza Research

by Alessandro Boianelli, Van Kinh Nguyen, Thomas Ebensen, Kai Schulze, Esther Wilk, Niharika Sharma, Sabine Stegemann-Koniszewski, Dunja Bruder, Franklin R. Toapanta, Carlos A. Guzmán, Michael Meyer-Hermann, Esteban A. Hernandez-Vargas
Published 2015-10-01

Self-Amplifying Pestivirus Replicon RNA Encoding Influenza Virus Nucleoprotein and Hemagglutinin Promote Humoral and Cellular Immune Responses in Pigs

by Thomas Démoulins, Thomas Démoulins, Nicolas Ruggli, Nicolas Ruggli, Markus Gerber, Markus Gerber, Lisa J. Thomann-Harwood, Lisa J. Thomann-Harwood, Thomas Ebensen, Kai Schulze, Carlos A. Guzmán, Kenneth C. McCullough, Kenneth C. McCullough
Published 2021-01-01

Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection against Influenza H5N1 in Mice

by Thomas Ebensen, Jennifer Debarry, Gabriel K. Pedersen, Gabriel K. Pedersen, Gabriel K. Pedersen, Paulina Blazejewska, Sebastian Weissmann, Kai Schulze, Kenneth C. McCullough, Rebecca J. Cox, Rebecca J. Cox, Rebecca J. Cox, Carlos A. Guzmán
Published 2017-09-01

Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi

by Andrés Sanchez Alberti, Andrés Sanchez Alberti, Andrés Sanchez Alberti, Augusto E. Bivona, Augusto E. Bivona, Marina N. Matos, Marina N. Matos, Natacha Cerny, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Germán González, Celina Morales, Alejandro C. Cardoso, Alejandro C. Cardoso, Silvia I. Cazorla, Silvia I. Cazorla, Carlos A. Guzmán, Emilio L. Malchiodi, Emilio L. Malchiodi
Published 2020-02-01