THE ROLE OF IMMUNOLOGY IN COMBATING TRYPANOSOMA CRUZI INFECTION AND CHAGAS DISEASE

by Rick L. Tarleton
Published 2013-01-01

Regulation of lymphokine production in experimental and human chagas' disease

by Rick L. Tarleton
Published 1988-11-01

Is Chagas disease really the "new HIV/AIDS of the Americas"?

by Rick L Tarleton, James W Curran
Published 2012-01-01

A systematic review of high quality diagnostic tests for Chagas disease.

by Anna M Afonso, Mark H Ebell, Rick L Tarleton
Published 2012-01-01

Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection.

by Angela D Pack, Matthew H Collins, Charles S Rosenberg, Rick L Tarleton
Published 2018-11-01

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

by Fernando J Sánchez-Valdéz, Angel Padilla, Wei Wang, Dylan Orr, Rick L Tarleton
Published 2018-03-01

The challenges of Chagas Disease-- grim outlook or glimmer of hope.

by Rick L Tarleton, Richard Reithinger, Julio A Urbina, Uriel Kitron, Ricardo E Gürtler
Published 2007-12-01

Chagas disease and the london declaration on neglected tropical diseases.

by Rick L Tarleton, Ricardo E Gürtler, Julio A Urbina, Janine Ramsey, Rodolfo Viotti
Published 2014-10-01

Knockout of the dhfr-ts gene in Trypanosoma cruzi generates attenuated parasites able to confer protection against a virulent challenge.

by Cecilia Perez Brandan, Angel M Padilla, Dan Xu, Rick L Tarleton, Miguel A Basombrio
Published 2011-12-01

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease.

by Wei Wang, Duo Peng, Rodrigo P Baptista, Yiran Li, Jessica C Kissinger, Rick L Tarleton
Published 2021-01-01

High throughput selection of effective serodiagnostics for Trypanosoma cruzi infection.

by Gretchen Cooley, R Drew Etheridge, Courtney Boehlke, Becky Bundy, D Brent Weatherly, Todd Minning, Matthew Haney, Miriam Postan, Susana Laucella, Rick L Tarleton
Published 2008-10-01

High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA.

by Angel M Padilla, Phil Y Yao, Tre J Landry, Gretchen M Cooley, Susan M Mahaney, Isabela Ribeiro, John L VandeBerg, Rick L Tarleton
Published 2021-03-01

In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds.

by Adriana M C Canavaci, Juan M Bustamante, Angel M Padilla, Cecilia M Perez Brandan, Laura J Simpson, Dan Xu, Courtney L Boehlke, Rick L Tarleton
Published 2010-07-01

Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease.

by Rafael J Argüello, María C Albareda, María G Alvarez, Graciela Bertocchi, Alejandro H Armenti, Carlos Vigliano, Patricia C Meckert, Rick L Tarleton, Susana A Laucella
Published 2012-01-01

HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease.

by María G Alvarez, Miriam Postan, D Brent Weatherly, María C Albareda, John Sidney, Alessandro Sette, Carina Olivera, Alejandro H Armenti, Rick L Tarleton, Susana A Laucella
Published 2008-01-01

Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins

by Lia Carolina Soares Medeiros, Lilith South, Duo Peng, Juan M. Bustamante, Wei Wang, Molly Bunkofske, Natasha Perumal, Fernando Sanchez-Valdez, Rick L. Tarleton, John C. Boothroyd
Published 2017-11-01

Treatment Success in Trypanosoma cruzi Infection Is Predicted by Early Changes in Serially Monitored Parasite-Specific T and B Cell Responses.

by María G Alvarez, Graciela L Bertocchi, Gretchen Cooley, María C Albareda, Rodolfo Viotti, Damián E Perez-Mazliah, Bruno Lococo, Melisa Castro Eiro, Susana A Laucella, Rick L Tarleton
Published 2016-04-01

Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection

by Andrés Sanchez Alberti, Augusto E. Bivona, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Celina Morales, Angel M. Padilla, Silvia I. Cazorla, Rick L. Tarleton, Carlos A. Guzmán, Emilio L. Malchiodi
Published 2017-04-01

Polyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults.

by María C Albareda, Ana M De Rissio, Gonzalo Tomas, Alicia Serjan, María G Alvarez, Rodolfo Viotti, Laura E Fichera, Mónica I Esteva, Daniel Potente, Alejandro Armenti, Rick L Tarleton, Susana A Laucella
Published 2013-01-01

CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes.

by Diana L Martin, D Brent Weatherly, Susana A Laucella, Melissa A Cabinian, Matthew T Crim, Susan Sullivan, Mark Heiges, Sarah H Craven, Charles S Rosenberg, Matthew H Collins, Alessandro Sette, Miriam Postan, Rick L Tarleton
Published 2006-08-01