1H-2,3-Dihydroperimidine Derivatives: A New Class of Potent Protein Tyrosine Phosphatase 1B Inhibitors

by Wen-Long Wang, Dong-Lin Yang, Li-Xin Gao, Chun-Lan Tang, Wei-Ping Ma, Hui-Hua Ye, Si-Qi Zhang, Ya-Nan Zhao, Hao-Jie Xu, Zhao Hu, Xia Chen, Wen-Hua Fan, Hai-Jun Chen, Jing-Ya Li, Fa-Jun Nan, Jia Li, Bainian Feng
Published 2013-12-01

Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans

by Jinyun Bai, Mingfeng Xia, Yaqian Xue, Fengguang Ma, Aoyuan Cui, Yixuan Sun, Yamei Han, Xi Xu, Feifei Zhang, Zhimin Hu, Zhengshuai Liu, Yuxiao Liu, Genxiang Cai, Weitong Su, Xiaoyang Sun, Haifu Wu, Hongmei Yan, Xinxia Chang, Xiqi Hu, Hua Bian, Pu Xia, Jing Gao, Yu Li, Xin Gao
Published 2020-07-01

Precancerous stem cells have the potential for both benign and malignant differentiation.

by Li Chen, Rulong Shen, Yin Ye, Xin-An Pu, Xingluo Liu, Wenrui Duan, Jing Wen, Jason Zimmerer, Ying Wang, Yan Liu, Larry C Lasky, Nyla A Heerema, Danilo Perrotti, Keiko Ozato, Satomi Kuramochi-Miyagawa, Toru Nakano, Allen J Yates, William E Carson, Haifan Lin, Sanford H Barsky, Jian-Xin Gao
Published 2007-03-01

Construction of Interferon-Gamma-Related Gene Signature to Characterize the Immune-Inflamed Phenotype of Glioblastoma and Predict Prognosis, Efficacy of Immunotherapy and Radiother...

by Hang Ji, Hang Ji, Yixu Ba, Yixu Ba, Shuai Ma, Shuai Ma, Kuiyuan Hou, Kuiyuan Hou, Shan Mi, Shan Mi, Xin Gao, Jiaqi Jin, Jiaqi Jin, Qin Gong, Ting Liu, Fang Wang, Fang Wang, Zhihui Liu, Zhihui Liu, Shupeng Li, Jianyang Du, Jianyang Du, Shaoshan Hu, Shaoshan Hu
Published 2021-09-01

Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer

by Bernard Pereira, Christopher T. Chen, Lipika Goyal, Charlotte Walmsley, Christopher J. Pinto, Islam Baiev, Read Allen, Laura Henderson, Supriya Saha, Stephanie Reyes, Martin S. Taylor, Donna M. Fitzgerald, Maida Williams Broudo, Avinash Sahu, Xin Gao, Wendy Winckler, A. Rose Brannon, Jeffrey A. Engelman, Rebecca Leary, James R. Stone, Catarina D. Campbell, Dejan Juric
Published 2021-05-01

Deep Learning Predicts Overall Survival of Patients With Unresectable Hepatocellular Carcinoma Treated by Transarterial Chemoembolization Plus Sorafenib

by Lei Zhang, Wei Xia, Zhi-Ping Yan, Zhi-Ping Yan, Jun-Hui Sun, Bin-Yan Zhong, Zhong-Heng Hou, Min-Jie Yang, Min-Jie Yang, Guan-Hui Zhou, Wan-Sheng Wang, Xing-Yu Zhao, Jun-Ming Jian, Peng Huang, Rui Zhang, Shen Zhang, Jia-Yi Zhang, Zhi Li, Xiao-Li Zhu, Xin Gao, Cai-Fang Ni
Published 2020-09-01

Age-Specific Cutoff Value for the Application of Percent Free Prostate-Specific Antigen (PSA) in Chinese Men with Serum PSA Levels of 4.0-10.0 ng/ml.

by Rui Chen, Yiran Huang, Xiaobing Cai, Liping Xie, Dalin He, Liqun Zhou, Chuanliang Xu, Xu Gao, Shancheng Ren, Fubo Wang, Lulin Ma, Qiang Wei, Changjun Yin, Ye Tian, Zhongquan Sun, Qiang Fu, Qiang Ding, Junhua Zheng, Zhangqun Ye, Dingwei Ye, Danfeng Xu, Jianquan Hou, Kexin Xu, Jianlin Yuan, Xin Gao, Chunxiao Liu, Tiejun Pan, Yinghao Sun, Chinese Prostate Cancer Consortium
Published 2015-01-01

Analysis of transcript-deleterious variants in Mendelian disorders: implications for RNA-based diagnostics

by Sateesh Maddirevula, Hiroyuki Kuwahara, Nour Ewida, Hanan E. Shamseldin, Nisha Patel, Fatema Alzahrani, Tarfa AlSheddi, Eman AlObeid, Mona Alenazi, Hessa S. Alsaif, Maha Alqahtani, Maha AlAli, Hatoon Al Ali, Rana Helaby, Niema Ibrahim, Firdous Abdulwahab, Mais Hashem, Nadine Hanna, Dorota Monies, Nada Derar, Afaf Alsagheir, Amal Alhashem, Badr Alsaleem, Hamoud Alhebbi, Sami Wali, Ramzan Umarov, Xin Gao, Fowzan S. Alkuraya
Published 2020-06-01

Characteristics, Management, and Outcomes of Acute Heart Failure in the Emergency Department: A Multicenter Registry Study with 1-year Follow-up in a Chinese Cohort in Beijing

by Guo-Gan Wang, Si-Jia Wang, Jian Qin, Chun-Sheng Li, Xue-Zhong Yu, Hong Shen, Li-Pei Yang, Yan Fu, Ya-An Zheng, Bin Zhao, Dong-Min Yu, Fu-Jun Qin, De-Gui Zhou, Ying Li, Fu-Jun Liu, Wei Li, Wei Zhao, Xin Gao, Zheng Wang, Ming Jin, Hong Zeng, Yi Li, Guo-Xing Wang, Hong Zhou, Xiao-Lu Sun, Peng-Bo Wang, Kam-Sang Woo
Published 2017-01-01

Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis.

by Giovanni Musso, Roberto Gambino, James H Tabibian, Mattias Ekstedt, Stergios Kechagias, Masahide Hamaguchi, Rolf Hultcrantz, Hannes Hagström, Seung Kew Yoon, Phunchai Charatcharoenwitthaya, Jacob George, Francisco Barrera, Svanhildur Hafliðadóttir, Einar Stefan Björnsson, Matthew J Armstrong, Laurence J Hopkins, Xin Gao, Sven Francque, An Verrijken, Yusuf Yilmaz, Keith D Lindor, Michael Charlton, Robin Haring, Markus M Lerch, Rainer Rettig, Henry Völzke, Seungho Ryu, Guolin Li, Linda L Wong, Mariana Machado, Helena Cortez-Pinto, Kohichiroh Yasui, Maurizio Cassader
Published 2014-07-01

Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans

by Henry J. Sutton, Racheal Aye, Azza H. Idris, Rachel Vistein, Eunice Nduati, Oscar Kai, Jedida Mwacharo, Xi Li, Xin Gao, T. Daniel Andrews, Marios Koutsakos, Thi H.O. Nguyen, Maxim Nekrasov, Peter Milburn, Auda Eltahla, Andrea A. Berry, Natasha KC, Sumana Chakravarty, B. Kim Lee Sim, Adam K. Wheatley, Stephen J. Kent, Stephen L. Hoffman, Kirsten E. Lyke, Philip Bejon, Fabio Luciani, Katherine Kedzierska, Robert A. Seder, Francis M. Ndungu, Ian A. Cockburn
Published 2021-02-01

Percent free prostate-specific antigen is effective to predict prostate biopsy outcome in Chinese men with prostate-specific antigen between 10.1 and 20.0 ng ml−1

by Rui Chen, Li-Qun Zhou, Xiao-Bing Cai, Li-Ping Xie, Yi-Ran Huang, Da-Lin He, Xu Gao, Chuan-Liang Xu, Qiang Ding, Qiang Wei, Chang-Jun Yin, Shan-Cheng Ren, Fu-Bo Wang, Ye Tian, Zhong-Quan Sun, Qiang Fu, Lu-Lin Ma, Jun-Hua Zheng, Zhang-Qun Ye, Ding-Wei Ye, Dan-Feng Xu, Jian-Quan Hou, Ke-Xin Xu, Jian-Lin Yuan, Xin Gao, Chun-Xiao Liu, Tie-Jun Pan, Ying-Hao Sun, on behalf of Chinese Prostate Cancer Consortium
Published 2015-01-01

The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses

by Jun Deng, Qian Chen, Zhian Chen, Kaili Liang, Xin Gao, Xiaohui Wang, Fadzai V. Makota, Hong Sheng Ong, Yanmin Wan, Kaiming Luo, Dongcheng Gong, Xiang Yu, Sarina Camuglia, Qunxiong Zeng, Tao Zhou, Feng Xue, Jing He, Yunbo Wei, Fan Xiao, Jianyang Ma, Danika L. Hill, Wim Pierson, Thi H. O. Nguyen, Haibo Zhou, Yan Wang, Wei Shen, Lingyun Sun, Zhanguo Li, Qiang Xia, Kun Qian, Lilin Ye, Steven Rockman, Michelle A. Linterman, Katherine Kedzierska, Nan Shen, Liwei Lu, Di Yu
Published 2021-05-01

Description and Climate Simulation Performance of CAS‐ESM Version 2

by He Zhang, Minghua Zhang, Jiangbo Jin, Kece Fei, Duoying Ji, Chenglai Wu, Jiawen Zhu, Juanxiong He, Zhaoyang Chai, Jinbo Xie, Xiao Dong, Dongling Zhang, Xunqiang Bi, Hang Cao, Huansheng Chen, Kangjun Chen, Xueshun Chen, Xin Gao, Huiqun Hao, Jinrong Jiang, Xianghui Kong, Shigang Li, Yangchun Li, Pengfei Lin, Zhaohui Lin, Hailong Liu, Xiaohong Liu, Ying Shi, Mirong Song, Huijun Wang, Tianyi Wang, Xiaocong Wang, Zifa Wang, Ying Wei, Baodong Wu, Zhenghui Xie, Yongfu Xu, Yongqiang Yu, Liang Yuan, Qingcun Zeng, Xiaodong Zeng, Shuwen Zhao, Guangqing Zhou, Jiang Zhu
Published 2020-12-01

Association of Genetic Variants Affecting microRNAs and Pancreatic Cancer Risk

by Ye Lu, Ye Lu, Chiara Corradi, Manuel Gentiluomo, Evangelina López de Maturana, George E. Theodoropoulos, Susanne Roth, Evaristo Maiello, Luca Morelli, Livia Archibugi, Livia Archibugi, Livia Archibugi, Jakob R. Izbicki, Patricia Sarlós, Vytautas Kiudelis, Martin Oliverius, Mateus Nóbrega Aoki, Yogesh Vashist, Casper H. J. van Eijck, Maria Gazouli, Renata Talar-Wojnarowska, Andrea Mambrini, Raffaele Pezzilli, Bas Bueno-de-Mesquita, Péter Hegyi, Péter Hegyi, Pavel Souček, John P. Neoptolemos, Gregorio Di Franco, Cosimo Sperti, Emanuele F. Kauffmann, Viktor Hlaváč, Faik G. Uzunoğlu, Stefano Ermini, Ewa Małecka-Panas, Maurizio Lucchesi, Giuseppe Vanella, Giuseppe Vanella, Giuseppe Vanella, Frederike Dijk, Beatrice Mohelníková-Duchoňová, Franco Bambi, Maria Chiara Petrone, Krzysztof Jamroziak, Feng Guo, Feng Guo, Katerina Kolarova, Giovanni Capretti, Giovanni Capretti, Anna Caterina Milanetto, Laura Ginocchi, Martin Loveček, Marta Puzzono, Hanneke W. M. van Laarhoven, Silvia Carrara, Audrius Ivanauskas, Konstantinos Papiris, Daniela Basso, Paolo G. Arcidiacono, Ferenc Izbéki, Roger Chammas, Roger Chammas, Pavel Vodicka, Pavel Vodicka, Pavel Vodicka, Thilo Hackert, Claudio Pasquali, Maria L. Piredda, Eithne Costello-Goldring, Giulia Martina Cavestro, Andrea Szentesi, Andrea Szentesi, Francesca Tavano, Barbara Włodarczyk, Hermann Brenner, Hermann Brenner, Hermann Brenner, Edita Kreivenaite, Xin Gao, Xin Gao, Stefania Bunduc, Stefania Bunduc, Roel C. H. Vermeulen, Martin A. Schneider, Anna Latiano, Domenica Gioffreda, Sabrina G. G. Testoni, Juozas Kupcinskas, Rita T. Lawlor, Gabriele Capurso, Gabriele Capurso, Gabriele Capurso, Núria Malats, Daniele Campa, Federico Canzian
Published 2021-08-01

Application of fluorescence in situ hybridization in the detection of bladder transitional-cell carcinoma: A multi-center clinical study based on Chinese population

by Liqun Zhou, Kaiwei Yang, Xuesong Li, Yi Ding, Dawei Mu, Hanzhong Li, Yong Yan, Jinyi Li, Dongwen Wang, Wei Li, Yulong Cong, Jiangping Gao, Kewei Ma, Yajun Xiao, Sheng Zhang, Hongyi Jiang, Weilie Hu, Qiang Wei, Xunbo Jin, Zhichen Guan, Qingyong Liu, Danfeng Xu, Xin Gao, Yongguang Jiang, Weimin Gan, Guang Sun, Qing Wang, Yanhui Liu, Jianquan Hou, Liping Xie, Xishuang Song, Fengshuo Jin, Jiafu Feng, Ming Cai, Zhaozhao Liang, Jie Zhang, Dingwei Ye, Lin Qi, Lulin Ma, Jianzhong Shou, Yuping Dai, Jianyong Shao, Ye Tian, Shizhe Hong, Tao Xu, Chuize Kong, Zefeng Kang, Yuexin Liu, Xun Qu, Benkang Shi, Shaobin Zheng, Yi Lin, Shujie Xia, Dong Wei, Jianbo Wu, Weiling Fu, Zhiping Wang, Jianbo Liang
Published 2019-01-01

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma

by Ziad Bakouny, David A. Braun, Sachet A. Shukla, Wenting Pan, Xin Gao, Yue Hou, Abdallah Flaifel, Stephen Tang, Alice Bosma-Moody, Meng Xiao He, Natalie Vokes, Jackson Nyman, Wanling Xie, Amin H. Nassar, Sarah Abou Alaiwi, Ronan Flippot, Gabrielle Bouchard, John A. Steinharter, Pier Vitale Nuzzo, Miriam Ficial, Miriam Sant’Angelo, Juliet Forman, Jacob E. Berchuck, Shaan Dudani, Kevin Bi, Jihye Park, Sabrina Camp, Maura Sticco-Ivins, Laure Hirsch, Sylvan C. Baca, Megan Wind-Rotolo, Petra Ross-Macdonald, Maxine Sun, Gwo-Shu Mary Lee, Steven L. Chang, Xiao X. Wei, Bradley A. McGregor, Lauren C. Harshman, Giannicola Genovese, Leigh Ellis, Mark Pomerantz, Michelle S. Hirsch, Matthew L. Freedman, Michael B. Atkins, Catherine J. Wu, Thai H. Ho, W. Marston Linehan, David F. McDermott, Daniel Y. C. Heng, Srinivas R. Viswanathan, Sabina Signoretti, Eliezer M. Van Allen, Toni K. Choueiri
Published 2021-02-01