Innate Immune Memory in Hematopoietic Stem/Progenitor Cells: Myeloid-Biased Differentiation and the Role of Interferon

by Lili Chen, Keiko Ozato
Published 2021-03-01

Autoantigen TRIM21/Ro52 as a Possible Target for Treatment of Systemic Lupus Erythematosus

by Ryusuke Yoshimi, Yoshiaki Ishigatsubo, Keiko Ozato
Published 2012-01-01

Clinical and Pathological Roles of Ro/SSA Autoantibody System

by Ryusuke Yoshimi, Atsuhisa Ueda, Keiko Ozato, Yoshiaki Ishigatsubo
Published 2012-01-01

Inflammatory monocyte-derived dendritic cells mediate autoimmunity in murine model of systemic lupus erythematosus

by Fumi Miyagawa, Yutaka Tagaya, Keiko Ozato, Kyoji Horie, Hideo Asada
Published 2020-01-01

Activation of JNK triggers release of Brd4 from mitotic chromosomes and mediates protection from drug-induced mitotic stress.

by Akira Nishiyama, Anup Dey, Tomohiko Tamura, Minoru Ko, Keiko Ozato
Published 2012-01-01

ZFR coordinates crosstalk between RNA decay and transcription in innate immunity

by Nazmul Haque, Ryota Ouda, Chao Chen, Keiko Ozato, J. Robert Hogg
Published 2018-03-01

Viral infection increases glucocorticoid-induced interleukin-10 production through ERK-mediated phosphorylation of the glucocorticoid receptor in dendritic cells: potential clinica...

by Sinnie Sin Man Ng, Andrew Li, George N Pavlakis, Keiko Ozato, Tomoshige Kino
Published 2013-01-01

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

by Takahiro Masuda, Makoto Tsuda, Ryohei Yoshinaga, Hidetoshi Tozaki-Saitoh, Keiko Ozato, Tomohiko Tamura, Kazuhide Inoue
Published 2012-04-01

IRF1 Maintains Optimal Constitutive Expression of Antiviral Genes and Regulates the Early Antiviral Response

by Debasis Panda, Erisa Gjinaj, Mahesh Bachu, Erica Squire, Hilary Novatt, Keiko Ozato, Ronald L. Rabin
Published 2019-05-01

Virus-like particles activate type I interferon pathways to facilitate post-exposure protection against Ebola virus infection.

by Natarajan Ayithan, Steven B Bradfute, Scott M Anthony, Kelly S Stuthman, Sina Bavari, Mike Bray, Keiko Ozato
Published 2015-01-01

Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery.

by Tsung-Hsien Chang, Toru Kubota, Mayumi Matsuoka, Steven Jones, Steven B Bradfute, Mike Bray, Keiko Ozato
Published 2009-06-01

Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation

by Anne Gegonne, Qing-Rong Chen, Anup Dey, Ruth Etzensperger, Xuguang Tai, Alfred Singer, Daoud Meerzaman, Keiko Ozato, Dinah S. Singer
Published 2018-07-01

HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis

by Chao Chen, Ming-an Sun, Claude Warzecha, Mahesh Bachu, Anup Dey, Tiyun Wu, Peter D Adams, Todd Macfarlan, Paul Love, Keiko Ozato
Published 2020-02-01

Mechanisms of immunity in post-exposure vaccination against Ebola virus infection.

by Steven B Bradfute, Scott M Anthony, Kelly S Stuthman, Natarajan Ayithan, Prafullakumar Tailor, Carl I Shaia, Mike Bray, Keiko Ozato, Sina Bavari
Published 2015-01-01

Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis

by Ji-Eun Lee, Young-Kwon Park, Sarah Park, Younghoon Jang, Nicholas Waring, Anup Dey, Keiko Ozato, Binbin Lai, Weiqun Peng, Kai Ge
Published 2017-12-01

Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors

by Daisuke Kurotaki, Jun Nakabayashi, Akira Nishiyama, Haruka Sasaki, Wataru Kawase, Naofumi Kaneko, Kyoko Ochiai, Kazuhiko Igarashi, Keiko Ozato, Yutaka Suzuki, Tomohiko Tamura
Published 2018-03-01

TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis

by Yosuke Kunishita, Ryusuke Yoshimi, Reikou Kamiyama, Daiga Kishimoto, Koji Yoshida, Eijin Hashimoto, Takaaki Komiya, Natsuki Sakurai, Yumiko Sugiyama, Yohei Kirino, Keiko Ozato, Hideaki Nakajima
Published 2020-02-01

IRF-8 regulates expansion of myeloid-derived suppressor cells and Foxp3+ regulatory T cells and modulates Th2 immune responses to gastrointestinal nematode infection.

by Rajesh M Valanparambil, Mifong Tam, Pierre-Paul Gros, Jean-Philippe Auger, Mariela Segura, Philippe Gros, Armando Jardim, Timothy G Geary, Keiko Ozato, Mary M Stevenson
Published 2017-10-01

Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development.

by Michio Yamamoto, Takayuki Kato, Chie Hotta, Akira Nishiyama, Daisuke Kurotaki, Masahiro Yoshinari, Masamichi Takami, Motohide Ichino, Masatoshi Nakazawa, Toshifumi Matsuyama, Ryutaro Kamijo, Seiichi Kitagawa, Keiko Ozato, Tomohiko Tamura
Published 2011-01-01

DNA Damage Induces Dynamic Associations of BRD4/P-TEFb With Chromatin and Modulates Gene Transcription in a BRD4-Dependent and -Independent Manner

by Yawei Song, Yawei Song, Yawei Song, Yawei Song, Yawei Song, Gongcheng Hu, Gongcheng Hu, Gongcheng Hu, Gongcheng Hu, Jinping Jia, Mingze Yao, Xiaoshan Wang, Wenliang Lu, Andrew P. Hutchins, Jiekai Chen, Jiekai Chen, Jiekai Chen, Keiko Ozato, Hongjie Yao, Hongjie Yao, Hongjie Yao, Hongjie Yao
Published 2020-12-01