Intracellular Protein Degradation: From a Vague Idea through the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting

by Aaron Ciechanover
Published 2012-01-01

Fred W. van Leeuwen (1949–2021)

by Bert M. Verheijen, Aaron Ciechanover
Published 2021-03-01

A novel small molecule CXCR4 antagonist potently mobilizes hematopoietic stem cells in mice and monkeys

by Xiao Fang, Xiong Fang, Yujia Mao, Aaron Ciechanover, Yan Xu, Jing An, Ziwei Huang
Published 2021-01-01

Switches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination system.

by Lan K Nguyen, Javier Muñoz-García, Helene Maccario, Aaron Ciechanover, Walter Kolch, Boris N Kholodenko
Published 2011-12-01

KRAS/NRAS/BRAF Mutations as Potential Targets in Multiple Myeloma

by Sergiu Pasca, Ciprian Tomuleasa, Ciprian Tomuleasa, Ciprian Tomuleasa, Patric Teodorescu, Patric Teodorescu, Gabriel Ghiaur, Delia Dima, Vlad Moisoiu, Cristian Berce, Cristina Stefan, Aaron Ciechanover, Herman Einsele
Published 2019-10-01

Downregulation of the Ubiquitin-E3 Ligase RNF123 Promotes Upregulation of the NF-κB1 Target SerpinE1 in Aggressive Glioblastoma Tumors

by Xiaowen Wang, Matias A. Bustos, Xiaoqing Zhang, Romela Irene Ramos, Cong Tan, Yuuki Iida, Shu-Ching Chang, Matthew P. Salomon, Kevin Tran, Rebecca Gentry, Yelena Kravtsova-Ivantsiv, Daniel F. Kelly, Gordon B. Mills, Aaron Ciechanover, Ying Mao, Dave S.B. Hoon
Published 2020-04-01

p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

by Hyunjoo Cha-Molstad, Ji Eun Yu, Zhiwei Feng, Su Hyun Lee, Jung Gi Kim, Peng Yang, Bitnara Han, Ki Woon Sung, Young Dong Yoo, Joonsung Hwang, Terry McGuire, Sang Mi Shim, Hyun Dong Song, Srinivasrao Ganipisetti, Nuozhou Wang, Jun Min Jang, Min Jae Lee, Seung Jun Kim, Kyung Ho Lee, Jin Tae Hong, Aaron Ciechanover, Inhee Mook-Jung, Kwang Pyo Kim, Xiang-Qun Xie, Yong Tae Kwon, Bo Yeon Kim
Published 2017-07-01