Systems biology informed neural networks (SBINN) predict response and novel combinations for PD-1 checkpoint blockade

by Michelle Przedborski, Munisha Smalley, Saravanan Thiyagarajan, Aaron Goldman, Mohammad Kohandel
Published 2021-07-01

Perspective on nanochannels as cellular mediators in different disease conditions

by Eshna Jash, Peeyush Prasad, Naveen Kumar, Taruna Sharma, Aaron Goldman, Seema Sehrawat
Published 2018-11-01

The Na+/H+ exchanger controls deoxycholic acid-induced apoptosis by a H+-activated, Na+-dependent ionic shift in esophageal cells.

by Aaron Goldman, HwuDauRw Chen, Mohammad R Khan, Heather Roesly, Kimberly A Hill, Mohammad Shahidullah, Amritlal Mandal, Nicholas A Delamere, Katerina Dvorak
Published 2011-01-01

Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer.

by Morgan Craig, Kamran Kaveh, Alec Woosley, Andrew S Brown, David Goldman, Elliot Eton, Ravindra M Mehta, Andrew Dhawan, Kazuya Arai, M Mamunur Rahman, Sidi Chen, Martin A Nowak, Aaron Goldman
Published 2019-08-01

Integrating Systems Biology and an Ex Vivo Human Tumor Model Elucidates PD-1 Blockade Response Dynamics

by Munisha Smalley, Michelle Przedborski, Saravanan Thiyagarajan, Moriah Pellowe, Amit Verma, Nilesh Brijwani, Debika Datta, Misti Jain, Basavaraja U. Shanthappa, Vidushi Kapoor, Kodaganur S. Gopinath, D.C. Doval, K.S. Sabitha, Gaspar Taroncher-Oldenburg, Biswanath Majumder, Pradip Majumder, Mohammad Kohandel, Aaron Goldman
Published 2020-06-01

Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm

by Xinan H Yang, Rangarajan D Nadadur, Catharina RE Hilvering, Valerio Bianchi, Michael Werner, Stefan R Mazurek, Margaret Gadek, Kaitlyn M Shen, Joseph Aaron Goldman, Leonid Tyan, Jenna Bekeny, Johnathon M Hall, Nutishia Lee, Carlos Perez-Cervantes, Ozanna Burnicka-Turek, Kenneth D Poss, Christopher R Weber, Wouter de Laat, Alexander J Ruthenburg, Ivan P Moskowitz
Published 2017-12-01