The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

by Margaret E Torrence, Michael R MacArthur, Aaron M Hosios, Alexander J Valvezan, John M Asara, James R Mitchell, Brendan D Manning
Published 2021-03-01

Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer

by Alba Luengo, Keene L. Abbott, Shawn M. Davidson, Aaron M. Hosios, Brandon Faubert, Sze Ham Chan, Elizaveta Freinkman, Lauren G. Zacharias, Thomas P. Mathews, Clary B. Clish, Ralph J. DeBerardinis, Caroline A. Lewis, Matthew G. Vander Heiden
Published 2019-12-01