Plinabulin, a Distinct Microtubule-Targeting Chemotherapy, Promotes M1-Like Macrophage Polarization and Anti-tumor Immunity

by Marina Natoli, Marina Natoli, Petra Herzig, Petra Herzig, Elham Pishali Bejestani, Elham Pishali Bejestani, Melanie Buchi, Melanie Buchi, Reto Ritschard, Reto Ritschard, G. Kenneth Lloyd, Ramon Mohanlal, James R. Tonra, Lan Huang, Viola Heinzelmann, Viola Heinzelmann, Marta Trüb, Marta Trüb, Alfred Zippelius, Alfred Zippelius, Abhishek S. Kashyap, Abhishek S. Kashyap
Published 2021-03-01

Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity

by Abhishek S. Kashyap, Tamara Thelemann, Richard Klar, Sandra M. Kallert, Julia Festag, Melanie Buchi, Lisa Hinterwimmer, Monika Schell, Sven Michel, Frank Jaschinski, Alfred Zippelius
Published 2019-03-01

GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses

by Abhishek S. Kashyap, Laura Fernandez-Rodriguez, Yun Zhao, Gianni Monaco, Marcel P. Trefny, Naohiro Yoshida, Kea Martin, Ashwani Sharma, Natacha Olieric, Pankaj Shah, Michal Stanczak, Nicole Kirchhammer, Sung-Moo Park, Sebastien Wieckowski, Heinz Laubli, Rachid Zagani, Benjamin Kasenda, Michel O. Steinmetz, Hans-Christian Reinecker, Alfred Zippelius
Published 2019-09-01

Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer

by Alfred Zippelius, Petra Herzig, Heinz Läubli, Gieri Cathomas, Christian Klein, Marta Trüb, Franziska Uhlenbrock, Christina Claus, Martin Thelen, Marina Bacac, Maria Amann, Rosemarie Albrecht, Claudia Ferrara-Koller, Daniela Thommen, Sacha Rothschield, Spasenija Savic Prince, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Abhishek S Kashyap
Published 2020-07-01