TLR Stimulation Dynamically Regulates Heme and Iron Export Gene Expression in Macrophages

by Mary Philip, Edison Y. Chiu, Adeline M. Hajjar, Janis L. Abkowitz
Published 2016-01-01

Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness.

by Adeline M Hajjar, Robert K Ernst, Jaehun Yi, Cathy S Yam, Samuel I Miller
Published 2017-01-01

Role of TLR4 in Persistent Leptospira interrogans Infection: A Comparative In Vivo Study in Mice

by Nisha Nair, Mariana S. Guedes, Adeline M. Hajjar, Catherine Werts, Catherine Werts, Maria Gomes-Solecki
Published 2021-01-01

Homeostatic regulation of Salmonella-induced mucosal inflammation and injury by IL-23.

by Muyiwa Awoniyi, Samuel I Miller, Christopher B Wilson, Adeline M Hajjar, Kelly D Smith
Published 2012-01-01

Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during infection

by Amanda Robison, Deann T Snyder, Kelly Christensen, Emily Kimmel, Adeline M Hajjar, Mark A Jutila, Jodi F Hedges
Published 2019-10-01

Innate immune detection of flagellin positively and negatively regulates salmonella infection.

by Marvin A Lai, Ellen K Quarles, Américo H López-Yglesias, Xiaodan Zhao, Adeline M Hajjar, Kelly D Smith
Published 2013-01-01

Temporal and anatomical host resistance to chronic Salmonella infection is quantitatively dictated by Nramp1 and influenced by host genetic background.

by Wendy P Loomis, Matthew L Johnson, Alicia Brasfield, Marie-Pierre Blanc, Jaehun Yi, Samuel I Miller, Brad T Cookson, Adeline M Hajjar
Published 2014-01-01

Humanized TLR7/8 expression drives proliferative multisystemic histiocytosis in C57BL/6 mice.

by Jessica M Snyder, Piper M Treuting, Lee Nagy, Cathy Yam, Jaehun Yi, Alicia Brasfield, Lisa Phuong Anh Nguyen, Adeline M Hajjar
Published 2014-01-01

Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.

by Adeline M Hajjar, Robert K Ernst, Edgardo S Fortuno, Alicia S Brasfield, Cathy S Yam, Lindsay A Newlon, Tobias R Kollmann, Samuel I Miller, Christopher B Wilson
Published 2012-01-01

NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.

by T Eoin West, Nicolle D Myers, Narisara Chantratita, Wirongrong Chierakul, Direk Limmathurotsakul, Vanaporn Wuthiekanun, Edward A Miao, Adeline M Hajjar, Sharon J Peacock, H Denny Liggitt, Shawn J Skerrett
Published 2014-09-01

A Francisella mutant in lipid A carbohydrate modification elicits protective immunity.

by Duangjit Kanistanon, Adeline M Hajjar, Mark R Pelletier, Larry A Gallagher, Thomas Kalhorn, Scott A Shaffer, David R Goodlett, Laurence Rohmer, Mitchell J Brittnacher, Shawn J Skerrett, Robert K Ernst
Published 2008-02-01

A Novel Class of Small Molecule Agonists with Preference for Human over Mouse TLR4 Activation.

by Jason D Marshall, Darren S Heeke, Eileen Rao, Sean K Maynard, David Hornigold, Christopher McCrae, Neil Fraser, Andrey Tovchigrechko, Li Yu, Nicola Williams, Sarah King, Martin E Cooper, Adeline M Hajjar, Jennifer C Woo
Published 2016-01-01

CFTR dysregulation drives active selection of the gut microbiome.

by Stacey M Meeker, Kevin S Mears, Naseer Sangwan, Mitchell J Brittnacher, Eli J Weiss, Piper M Treuting, Nicholas Tolley, Christopher E Pope, Kyle R Hager, Anh T Vo, Jisun Paik, Charles W Frevert, Hillary S Hayden, Lucas R Hoffman, Samuel I Miller, Adeline M Hajjar
Published 2020-01-01

Ontogeny of Toll-like receptor mediated cytokine responses of human blood mononuclear cells.

by Nathan P Corbett, Darren Blimkie, Kevin C Ho, Bing Cai, Darren P Sutherland, Arlene Kallos, Juliet Crabtree, Annie Rein-Weston, Pascal M Lavoie, Stuart E Turvey, Natalie R Hawkins, Steven G Self, Christopher B Wilson, Adeline M Hajjar, Edgardo S Fortuno, Tobias R Kollmann
Published 2010-11-01