Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma

by Soumya R. Mohapatra, Ahmed Sadik, Ahmed Sadik, Lars-Oliver Tykocinski, Jørn Dietze, Gernot Poschet, Ines Heiland, Christiane A. Opitz, Christiane A. Opitz
Published 2019-12-01

Chicken eggs, childhood stunting and environmental hygiene: an ethnographic study from the Campylobacter genomics and environmental enteric dysfunction (CAGED) project in Ethiopia

by Kevin Louis Bardosh, Jeylan Wolyie Hussein, Elias Ahmed Sadik, Jemal Yousuf Hassen, Mengistu Ketema, Abdulmuen Mohammed Ibrahim, Sarah Lindley McKune, Arie Hendrik Havelaar
Published 2020-03-01

Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation

by Isabell Adam, Dyah L. Dewi, Joram Mooiweer, Ahmed Sadik, Soumya R. Mohapatra, Bianca Berdel, Melanie Keil, Jana K. Sonner, Kathrin Thedieck, Adam J. Rose, Michael Platten, Ines Heiland, Saskia Trump, Christiane A. Opitz
Published 2018-12-01

Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production

by Soumya R. Mohapatra, Ahmed Sadik, Suraj Sharma, Gernot Poschet, Hagen M. Gegner, Tobias V. Lanz, Tobias V. Lanz, Tobias V. Lanz, Philippe Lucarelli, Ursula Klingmüller, Ursula Klingmüller, Michael Platten, Michael Platten, Ines Heiland, Christiane A. Opitz, Christiane A. Opitz
Published 2021-02-01

Methylome analyses of three glioblastoma cohorts reveal chemotherapy sensitivity markers within DDR genes

by Tobias Kessler, Anne Berberich, Ahmed Sadik, Felix Sahm, Thierry Gorlia, Christoph Meisner, Dirk C. Hoffmann, Antje Wick, Philipp Kickingereder, Petra Rübmann, Martin Bendszus, Christiane Opitz, Michael Weller, Martin van denBent, Roger Stupp, Frank Winkler, Alba Brandes, Andreas vonDeimling, Michael Platten, Wolfgang Wick
Published 2020-11-01

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas

by Katrin Aslan, Verena Turco, Jens Blobner, Jana K. Sonner, Anna Rita Liuzzi, Nicolás Gonzalo Núñez, Donatella De Feo, Philipp Kickingereder, Manuel Fischer, Ed Green, Ahmed Sadik, Mirco Friedrich, Khwab Sanghvi, Michael Kilian, Frederik Cichon, Lara Wolf, Kristine Jähne, Anna von Landenberg, Lukas Bunse, Felix Sahm, Daniel Schrimpf, Jochen Meyer, Allen Alexander, Gianluca Brugnara, Ralph Röth, Kira Pfleiderer, Beate Niesler, Andreas von Deimling, Christiane Opitz, Michael O. Breckwoldt, Sabine Heiland, Martin Bendszus, Wolfgang Wick, Burkhard Becher, Michael Platten
Published 2020-02-01