Immunotherapy Breakthroughs in the Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

by Christian Borel, Alain C. Jung, Mickaël Burgy
Published 2020-09-01

The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response.

by E Douglas Robertson, Christine Wasylyk, Tao Ye, Alain C Jung, Bohdan Wasylyk
Published 2014-01-01

Constitutive or Induced HIF-2 Addiction is Involved in Resistance to Anti-EGFR Treatment and Radiation Therapy in HNSCC

by Pierre Coliat, Ludivine Ramolu, Jérémie Jégu, Christian Gaiddon, Alain C. Jung, Erwan Pencreach
Published 2019-10-01

The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development.

by Hélène Chanut-Delalande, Alain C Jung, Magdalena M Baer, Li Lin, François Payre, Markus Affolter
Published 2010-01-01

Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exci...

by Christian Gaiddon, Isabelle Gross, Xiangjun Meng, Marjorie Sidhoum, Georg Mellitzer, Benoit Romain, Jean-Batiste Delhorme, Aïna Venkatasamy, Alain C. Jung, Michel Pfeffer
Published 2021-09-01

Ultrasound and Transcriptomics Identify a Differential Impact of Cisplatin and Histone Deacetylation on Tumor Structure and Microenvironment in a Patient-Derived In Vivo Model of G...

by Aina Venkatasamy, Eric Guerin, Anais Blanchet, Christophe Orvain, Véronique Devignot, Matthieu Jung, Alain C. Jung, Marie-Pierre Chenard, Benoit Romain, Christian Gaiddon, Georg Mellitzer
Published 2021-09-01

HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway

by Marie-Elodie Spaety, Alexandre Gries, Amandine Badie, Aina Venkatasamy, Benoit Romain, Christophe Orvain, Kazuyoshi Yanagihara, Koji Okamoto, Alain C. Jung, Georg Mellitzer, Sébastien Pfeffer, Christian Gaiddon
Published 2019-11-01

Preferential Response of Basal-Like Head and Neck Squamous Cell Carcinoma Cell Lines to EGFR-Targeted Therapy Depending on <i>EREG</i>-Driven Oncogenic Addiction

by Sylvie Job, Aurélien de Reyniès, Betty Heller, Amélie Weiss, Eric Guérin, Christine Macabre, Sonia Ledrappier, Cyril Bour, Christine Wasylyk, Nelly Etienne-Selloum, Laurent Brino, Christian Gaiddon, Bohdan Wasylyk, Alain C. Jung
Published 2019-06-01

Cav1/EREG/YAP Axis in the Treatment Resistance of Cav1-Expressing Head and Neck Squamous Cell Carcinoma

by Mickaël Burgy, Aude Jehl, Ombline Conrad, Sophie Foppolo, Véronique Bruban, Nelly Etienne-Selloum, Alain C. Jung, Murielle Masson, Christine Macabre, Sonia Ledrappier, Hélène Burckel, Carole Mura, Georges Noël, Christian Borel, François Fasquelle, Mihaela-Alina Onea, Marie-Pierre Chenard, Alicia Thiéry, Monique Dontenwill, Sophie Martin
Published 2021-06-01