Signalling pathways implicated in early mammary gland morphogenesis and breast cancer.

by Beatrice Howard, Alan Ashworth
Published 2006-08-01

NLK is a novel therapeutic target for PTEN deficient tumour cells.

by Ana M Mendes-Pereira, Christopher J Lord, Alan Ashworth
Published 2012-01-01

A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers

by Gourish Mondal, Meredith Stevers, Benjamin Goode, Alan Ashworth, David A. Solomon
Published 2019-04-01

Klotho: A Major Shareholder in Vascular Aging Enterprises

by Kenneth Lim, Arvin Halim, Tzong-shi Lu, Alan Ashworth, Irene Chong
Published 2019-09-01

Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.

by Jeffrey C Francis, Afshan McCarthy, Martin K Thomsen, Alan Ashworth, Amanda Swain
Published 2010-06-01

Smoking and risk of breast cancer in the Generations Study cohort

by Michael E. Jones, Minouk J. Schoemaker, Lauren B. Wright, Alan Ashworth, Anthony J. Swerdlow
Published 2017-11-01

Klotho and the Treatment of Human Malignancies

by Aishani Sachdeva, Jerome Gouge, Christos Kontovounisios, Stella Nikolaou, Alan Ashworth, Kenneth Lim, Irene Chong
Published 2020-06-01

Correction to: Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study

by Danielle H. Bodicoat, Minouk J. Schoemaker, Michael E. Jones, Emily McFadden, James Griffin, Alan Ashworth, Anthony J. Swerdlow
Published 2020-02-01

Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets

by Dragomir B. Krastev, Stephen J. Pettitt, James Campbell, Feifei Song, Barbara E. Tanos, Stoyno S. Stoynov, Alan Ashworth, Christopher J. Lord
Published 2018-05-01

Lkb1 deficiency alters goblet and paneth cell differentiation in the small intestine.

by Boris Y Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B Pearson, Douglas J Winton, Owen J Sansom, Alan Ashworth, Alan R Clarke
Published 2009-01-01

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

by Boris Y. Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B. Pearson, Douglas J. Winton, Owen J. Sansom, Alan Ashworth, Alan R. Clarke
Published 2009-01-01

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine.

by Boris Y. Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B. Pearson, Douglas J. Winton, Owen J. Sansom, Alan Ashworth, Alan R. Clarke
Published 2009-01-01

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine.

by Boris Y Shorning, Joanna Zabkiewicz, Afshan McCarthy, Helen B Pearson, Douglas J Winton, Owen J Sansom, Alan Ashworth, Alan R Clarke
Published 2019-01-01

Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men.

by Nick Orr, Rosie Cooke, Michael Jones, Olivia Fletcher, Frank Dudbridge, Sarah Chilcott-Burns, Katarzyna Tomczyk, Peter Broderick, Richard Houlston, Alan Ashworth, Anthony Swerdlow
Published 2011-09-01

Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

by Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth
Published 2016-01-01

Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

by Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth
Published 2018-01-01

Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

by Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth
Published 2017-01-01

CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.

by Sara Costa-Cabral, Rachel Brough, Asha Konde, Marieke Aarts, James Campbell, Eliana Marinari, Jenna Riffell, Alberto Bardelli, Christopher Torrance, Christopher J Lord, Alan Ashworth
Published 2016-01-01

Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking

by George D. Cresswell, Daniel Nichol, Inmaculada Spiteri, Haider Tari, Luis Zapata, Timon Heide, Carlo C. Maley, Luca Magnani, Gaia Schiavon, Alan Ashworth, Peter Barry, Andrea Sottoriva
Published 2020-03-01

Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancer.

by Louise J Barber, Juan M Rosa Rosa, Iwanka Kozarewa, Kerry Fenwick, Ioannis Assiotis, Costas Mitsopoulos, David Sims, Jarle Hakas, Marketa Zvelebil, Christopher J Lord, Alan Ashworth
Published 2011-01-01