(Pro)renin Receptor-Dependent Induction of Profibrotic Factors Is Mediated by COX-2/EP4/NOX-4/Smad Pathway in Collecting Duct Cells

by Cristian Reyes-Martinez, Quynh My Nguyen, Modar Kassan, Alexis A. Gonzalez
Published 2019-07-01

Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats

by Alexis A. Gonzalez, Matias Gallardo, Carlos Cespedes, Carlos Cespedes, Carlos P. Vio, Carlos P. Vio
Published 2019-10-01

Upregulation of Cortical Renin and Downregulation of Medullary (Pro)Renin Receptor in Unilateral Ureteral Obstruction

by Stefanny M. Figueroa, Stefanny M. Figueroa, Mauricio Lozano, Carolina Lobos, Matthew T. Hennrikus, Alexis A. Gonzalez, Cristián A. Amador
Published 2019-11-01

High glucose induces trafficking of prorenin receptor and stimulates profibrotic factors in the collecting duct

by Venkateswara R. Gogulamudi, Danielle Y. Arita, Camille R. T. Bourgeois, Justine Jorgensen, Jing He, William C. Wimley, Ryosuke Satou, Alexis A. Gonzalez, Minolfa C. Prieto
Published 2021-07-01

Cyclooxygenase-2 and hypoxia-regulated proteins are modulated by basic fibroblast growth factor in acute renal failure

by Sandra Villanueva, Pía Escobar, Ioram Jacubovsky, Carlos Irarrázabal, Juan E Carreño, José M Erpel, Carlos Céspedes, Alexis A González, Carlos P Vio, Victoria Velarde
Published 2012-01-01

MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy

by Karima Ait-Aissa, Quynh My Nguyen, Mohanad Gabani, Adam Kassan, Santosh Kumar, Soo-Kyoung Choi, Alexis A. Gonzalez, Tahsin Khataei, Amal M. Sahyoun, Cheng Chen, Modar Kassan
Published 2020-09-01

α-Ketoglutarate Upregulates Collecting Duct (Pro)renin Receptor Expression, Tubular Angiotensin II Formation, and Na+ Reabsorption During High Glucose Conditions

by Aarón Guerrero, Bruna Visniauskas, Pilar Cárdenas, Stefanny M. Figueroa, Jorge Vivanco, Nicolas Salinas-Parra, Patricio Araos, Quynh My Nguyen, Modar Kassan, Cristián A. Amador, Minolfa C. Prieto, Alexis A. Gonzalez
Published 2021-06-01

Low Nitric Oxide Bioavailability Increases Renin Production in the Collecting Duct

by Andrew C. Curnow, Sabrina R. Gonsalez, Sabrina R. Gonsalez, Venkateswara R. Gogulamudi, Bruna Visniauskas, Eric E. Simon, Alexis A. Gonzalez, Dewan S. A. Majid, Dewan S. A. Majid, Lucienne S. Lara, Minolfa C. Prieto, Minolfa C. Prieto
Published 2020-11-01