Radiation dosimetry of [18F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans

by Bert-Ram Sah, Michael Sommerauer, Linjing Mu, Gloria Pla Gonzalez, Susanne Geistlich, Valerie Treyer, Roger Schibli, Alfred Buck, Geoffrey Warnock, Simon M. Ametamey
Published 2019-06-01

Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation

by Sebastian C Holst, Alexandra Sousek, Katharina Hefti, Sohrab Saberi-Moghadam, Alfred Buck, Simon M Ametamey, Milan Scheidegger, Paul Franken, Anke Henning, Erich Seifritz, Mehdi Tafti, Hans-Peter Landolt
Published 2017-10-01

Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia

by Valerie Treyer, Anton F. Gietl, Husam Suliman, Esmeralda Gruber, Rafael Meyer, Andreas Buchmann, Anass Johayem, Paul G. Unschuld, Roger M. Nitsch, Alfred Buck, Simon M. Ametamey, Christoph Hock
Published 2020-06-01

The impact of atlas-based MR attenuation correction on the diagnosis of FDG-PET/MR for Alzheimer's diseases- A simulation study combining multi-center data and ADNI-data.

by Tetsuro Sekine, Alfred Buck, Gaspar Delso, Bradley Kemp, Edwin E G W Ter Voert, Martin Huellner, Patrick Veit-Haibach, Sandeep Kaushik, Florian Wiesinger, Geoffrey Warnock, Alzheimer’s Disease Neuroimaging Initiative
Published 2020-01-01

Regional brain mGlu5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers

by Johannes Streffer, Valerie Treyer, Alfred Buck, Simon M. Ametamey, Milen Blagoev, Ralph P Maguire, Aurélie Gautier, Yves P. Auberson, Mark E. Schmidt, Ivan-Toma Vranesic, Baltazar Gomez-Mancilla, Fabrizio Gasparini
Published 2021-04-01

Brain areas with normatively greater cerebral perfusion in early life may be more susceptible to beta amyloid deposition in late life

by Irene B. Meier, Patrick J. Lao, Anton Gietl, Robert S. Vorburger, José Gutierrez, Christopher M. Holland, Charles R.G. Guttmann, Dominik S. Meier, Alfred Buck, Roger M. Nitsch, Christoph Hock, Paul G. Unschuld, Adam M. Brickman
Published 2020-01-01

Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer’s disease

by Frances C. Quevenco, Maria G. Preti, Jiri M. G. van Bergen, Jun Hua, Michael Wyss, Xu Li, Simon J. Schreiner, Stefanie C. Steininger, Rafael Meyer, Irene B. Meier, Adam M. Brickman, Sandra E. Leh, Anton F. Gietl, Alfred Buck, Roger M. Nitsch, Klaas P. Pruessmann, Peter C. M. van Zijl, Christoph Hock, Dimitri Van De Ville, Paul G. Unschuld
Published 2017-03-01